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8837 CFLAR

8837

CFLAR

CASP8 and FADD like apoptosis regulator

protein-coding

Homo sapiens

基因描述

Type Description
Definition CASP8 and FADD like apoptosis regulator

研究结论

Date Results Publications
2021-04-17 13:37:00 Superoxide induced inhibition of death receptor signaling is mediated via induced expression of apoptosis inhibitory protein cFLIP. 31954371
2021-03-20 13:32:00 Co-treatment of birinapant with TRAIL synergistically induces apoptosis by downregulating cFLIP(L) in MDA-MB-453 cell lines. 32958259
2020-11-28 13:12:00 Long and short isoforms of c-FLIP act as control checkpoints of DED filament assembly. 31740779
2020-08-15 19:05:00 Cisplatin unleashes Toll-like receptor 3-mediated apoptosis through the downregulation of c-FLIP in malignant mesothelioma. 31838086
2020-06-27 10:17:00 c-FLIP and NF-kappaB are both required for inhibiting cell death and ensuring survival in a complex CD95-FLIP-NF-kappaB-signaling circuit in renal cell carcinoma. 31097685

名称对应

Type IDs
Synonymous CASH, CASP8AP1, CLARP, Casper, FLAME, FLAME-1, FLAME1, FLIP, I-FLICE, MRIT, c-FLIP, c-FLIPL, c-FLIPR, c-FLIPS, cFLIP
Gene
UniProtKB-ID: CFLAR_HUMAN, B4E361_HUMAN, A0A336TY74_HUMAN, A0A024R3Y3_HUMAN, Q59F61_HUMAN, A0A024R3Y4_HUMAN, E9PAP3_HUMAN
UniprotKB: O15519, B4E361, A0A336TY74, A0A024R3Y3, Q59F61, A0A024R3Y4, E9PAP3
UniParc: UPI000002A640, UPI000002A63B, UPI00017A71FB, UPI0000001039, UPI00017A8859, UPI000002A63F, UPI00004F6D72, UPI0000030475, UPI000002A636, UPI0001639511, UPI000002A63D, UPI000002A638, UPI000002A63A, UPI000002A641, UPI000002A639, UPI000002A637, UPI000002A63C, UPI000002A63E
EMBL: AK304585, BT006751, AK289913, Y14040, BC001602, AF005774, AF015451, AF041458, AK315208, AF009617, AF015452, AK296036, AF041460, AF010127, CH471063, AC007283, Y14039, AF041461, U85059, AF005775, KR422625, U97075, AK315924, AB038972, AF041462, HM005351, AF009619, AF015450, AF009616, U97074, AB209600, AF041459, AF009618
Ensembl: ENSG00000003402
KO: hsa:8837
Nucleutide sequences
EMBL-CDS: BAB32552.1, AAC51623.1, AAB82648.1, CAA74366.1, AAC16441.1, AAB64110.1, EAW70237.1, AAC15825.1, CAA74367.1, AAH01602.1, AAC51622.1, AAP35397.1, AAB99793.1, AAB99791.1, BAB32551.1, BAG58802.1, AAB99794.1, AAB70909.1, BAG37645.1, AAB99792.1, AAC16440.1, EAW70244.1, BAF82602.1, AAB70910.1, AAC15826.1, AAB99790.1, AAC16439.1, AAY24290.1, AAB70911.1, BAH14295.1, AAB70912.1, BAG65373.1, AMY98472.1, EAW70235.1, EAW70238.1, EAW70240.1, BAD92837.1, EAW70245.1, AEE60951.1, EAW70243.1
Gene_ORFName: hCG_16553, hCG_16553, hCG_16553
Ensembl_TRS: ENST00000342795, ENST00000341222, ENST00000341582, ENST00000479953, ENST00000443227, ENST00000423241, ENST00000309955, ENST00000457277, ENST00000440180, ENST00000395148
Protein sequencees
Ensembl_PRO: ENSP00000471805, ENSP00000345807, ENSP00000312455, ENSP00000406775, ENSP00000342809, ENSP00000411535, ENSP00000399420, ENSP00000339335, ENSP00000413270, ENSP00000378580
RefSeq: NP_001120655.1, NP_001338522.1, NP_003870.4, NP_001189446.1, NP_001338521.1, NP_001338519.1, NP_001189445.1, NP_001338523.1, XP_016860682.1, NP_001189448.1, NP_001120656.1, XP_016860679.1, NP_001189447.1, NP_001338520.1, XP_016860680.1, XP_016860678.1, XP_016860684.1, NP_001189444.1, NP_001294972.1, NP_001294971.1
Others
UniRef100: UniRef100_A0A336TY74, UniRef100_O15519, UniRef100_E9PAP3, UniRef100_A0A024R3Y3, UniRef100_B4E361
UniRef90: UniRef90_E9PAP3, UniRef90_O15519, UniRef90_A0A0A0MR92
UniRef50: UniRef50_E9PAP3, UniRef50_O15519, UniRef50_A0A0A0MR92
UniGene: Hs.390736, Hs.731912
CCDS: CCDS56157.1, CCDS2337.1, CCDS59436.1, CCDS56158.1, CCDS46487.1, CCDS77505.1

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