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882442 oprP

882442

oprP

phosphate-specific outer membrane porin OprP

protein-coding

Pseudomonas aeruginosa PAO1

基因描述

Type Description
Definition phosphate-specific outer membrane porin OprP

研究结论

Date Results Publications
2017-12-30 12:41:00 Our analyzes show that OprO, and to a lesser degree OprP, have unexpected very high permeability to fosfomycin, so the antibiotic should be a potentially excellent alternative choice for the control of Pseudomonas aeruginosa infections. 29198700
2016-12-17 11:26:00 The results suggest that trimerization is crucial for both structure and function of general porin OmpF in E. coli, whereas being trimer in substrate-specific channel OprP supports a pore function in Pseudomonas aeruginosa. 26895142
2016-08-06 11:09:00 Study used x-ray crystallography, free-energy molecular dynamics (MD) simulations, and electrophysiology to uncover the atomic basis for the different substrate specificity of OprP and OprO 26445443
2013-11-30 10:47:00 Data indicate the role of the R133 residue - particularly its charge and ability to change the solvation behavior of the permeating ion - in the structure-function relationship of outer membrane porin OprP. 23875754

名称对应

Type IDs
Gene
UniProtKB-ID: PORP_PSEAE
UniprotKB: P05695
UniParc: UPI0000131F7F
EMBL: M86648, AE004091, X53313, Y00553
EnsemblGenome: PA3279
KO: pae:PA3279
Nucleutide sequences
EMBL-CDS: CAA68631.1, AAG06667.1, AAA25913.1, CAA37395.1
EnsemblGenome_TRS: AAG06667
Protein sequencees
EnsemblGenome_PRO: AAG06667
RefSeq: NP_251969.1
Others
UniRef100: UniRef100_P05695
UniRef90: UniRef90_P05695
UniRef50: UniRef50_P05695

全选

研究热度
该基因近6年没有文献发表
热点单位
排名 科研单位 文献
1

Simon Fraser University

2
2

University of Rochester School of Medicine and Dentistry

2
3

Jacobs University Bremen

2
4

PathoGenesis Corporation, Seattle, Washington 98119, USA.

1
5

Institute for Cell and Molecular Biosciences

1
热点人员
排名 研究人员 文献
1

Robert E W Hancock

3
2

Fiona S L Brinkman

2
3

Geoffrey L Winsor

2
4

Raymond Lo

2
5

Roland Benz

2
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