| Type | Description |
|---|---|
| Definition | succinate-CoA ligase GDP-forming beta subunit |
| Date | Results | Publications |
|---|---|---|
| 2020-12-19 13:44:00 | EGFR-upregulated LIFR promotes SUCLG2-dependent castration resistance and neuroendocrine differentiation of prostate cancer. | 32963351 |
| 2018-06-23 10:42:00 | SUCLG2 has a sensitivity of 75% and a specificity of 80% to distinguish follicular carcinoma from follicular adenoma | 28709933 |
| 2015-10-31 11:37:00 | The absence of SUCLA2 and SUCLG2 in human glia is in compliance with the presence of alternative pathways occurring in these cells, namely the GABA shunt and ketone body metabolism | 25370487 |
| 2015-07-25 10:09:00 | SUCLG2 has been identified as both a determinator of CSF amyloid beta-protein (1-42) levels and as attenuator of cognitive decline in Alzheimer's disease. | 25027320 |
| 2011-05-21 10:24:00 | Loss of SUCLG2 is associated with mitochondrial DNA depletion and results in mitochondrial depletion syndrome. | 21295139 |
| Type | IDs |
|---|---|
| Synonymous | G-SCS, GBETA, GTPSCS |
| Gene |
UniProtKB-ID:
SUCB2_HUMAN
UniprotKB:
Q96I99
UniParc:
UPI0000209977,
UPI000189265B
EMBL:
BC019868,
AC113169,
AF131748,
AK310527,
AF058954,
AC099783,
BC007716,
BC068602,
AC112213,
BC047024,
AC114401
Ensembl:
ENSG00000172340
KO:
hsa:8801
|
| Nucleutide sequences |
EMBL-CDS:
AAH68602.1,
AAH47024.1,
AAC64397.1,
AAH19868.1,
AAD20032.1,
AAH07716.3
Ensembl_TRS:
ENST00000307227,
ENST00000493112
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000307432,
ENSP00000419325
RefSeq:
XP_016862909.1,
NP_001171070.1,
NP_003839.2
|
| Others |
UniRef100:
UniRef100_Q96I99
UniRef90:
UniRef90_Q96I99
UniRef50:
UniRef50_Q96I99
UniGene:
Hs.644919
CCDS:
CCDS54605.1,
CCDS43104.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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