| Type | Description |
|---|---|
| Definition | membrane bound transcription factor peptidase, site 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-11-02 10:53:00 | Site-1 protease function is essential for the generation of antibody secreting cells and reprogramming for secretory activity | 30254311 |
| 2018-07-21 10:06:00 | rs11642644 associated with facial profile | 29301965 |
| 2018-02-10 10:40:00 | In the absence of S1P, the catalytically inactive alpha/beta-subunit precursor of GlcNAc-1-phosphotransferase fails to be activated and results in missorting of newly synthesized lysosomal enzymes, and lysosomal accumulation of non-degraded material, which are biochemical features of defective GlcNAc-1-phosphotransferase subunits and the associated pediatric lysosomal diseases mucolipidosis type II and III. | 28693924 |
| 2017-06-03 10:26:00 | Results suggest that (pro)renin receptor (s(P)RR) is generated by sequential processing by site-1 protease (S1P) and furin protein. | 28013223 |
| 2016-06-28 10:45:00 | primordial SKI-1/S1P likely contained a simpler prodomain consisting of the highly conserved AB fragment that represents an independent folding unit | 26645686 |
| Type | IDs |
|---|---|
| Synonymous | PCSK8, S1P, SKI-1 |
| Gene |
UniProtKB-ID:
MBTP1_HUMAN
UniprotKB:
Q14703
UniParc:
UPI0000033348
EMBL:
AL133583,
AC040169,
BC114555,
D42053,
AK291773,
BC114961
Ensembl:
ENSG00000140943
KO:
hsa:8720
|
| Nucleutide sequences |
EMBL-CDS:
AAI14556.1,
AAI14962.1,
CAB63727.1,
BAA07653.2,
BAF84462.1
Ensembl_TRS:
ENST00000343411
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000344223
RefSeq:
XP_016879305.1,
NP_003782.1,
XP_024306245.1,
XP_016879306.1
|
| Others |
UniRef100:
UniRef100_Q14703
UniRef90:
UniRef90_Q14703
UniRef50:
UniRef50_Q14703
UniGene:
Hs.75890
CCDS:
CCDS10941.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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