| Type | Description |
|---|---|
| Definition | NUMB endocytic adaptor protein |
| Date | Results | Publications |
|---|---|---|
| 2020-12-05 13:03:00 | Cooperation of SRPK2, Numb and p53 in the malignant biology and chemosensitivity of colorectal cancer. | 31898732 |
| 2020-11-21 13:19:00 | Musashi1 expression is negatively correlated with numb expression in brain metastases. | 33120728 |
| 2020-08-01 11:52:00 | Numb functions as a tumor suppressor in colorectal cancer, and its tumor suppressor function is mediated by negative regulation of the epithelial mesenchymal transition through the Wnt signaling pathway. | 32146835 |
| 2020-07-11 10:49:00 | HMGA1 knockdown-induced NUMB upregulation. | 31116627 |
| 2020-02-29 11:00:00 | Knockdown of NUMB endocytic adaptor protein (Numb could promote the epithelial mesenchymal transition (EMT) of breast cancer cells via beta-catenin/RNA binding protein Lin28 (Lin28) signal pathway. | 31095937 |
| Type | IDs |
|---|---|
| Synonymous | C14orf41, S171, c14_5527 |
| Gene |
UniProtKB-ID:
NUMB_HUMAN,
A0A024R6F4_HUMAN,
A0A024R684_HUMAN,
A0A024R681_HUMAN,
A0A024R6C4_HUMAN
UniprotKB:
P49757,
A0A024R6F4,
A0A024R684,
A0A024R681,
A0A024R6C4
UniParc:
UPI0001661B21,
UPI000002AFD5,
UPI000002AFD6,
UPI000002AFD4,
UPI0001661B24,
UPI0001661B23,
UPI0000E01637,
UPI0001661B22,
UPI00001309BF
EMBL:
AK304193,
AC004846,
AF109907,
BX248073,
EU265734,
AF108092,
EU265738,
BC068476,
EU265736,
CH471061,
AF171938,
AK294591,
AF171941,
EU265735,
AF171940,
BC020788,
AL391733,
AF015040,
EU265737,
AF171939,
L40393,
AC005280
Ensembl:
ENSG00000133961
KO:
hsa:8650
|
| Nucleutide sequences |
EMBL-CDS:
ABY89094.1,
AAH20788.1,
BAG65073.1,
CAD62362.1,
BAG57779.1,
ABY89093.1,
AAD54280.1,
AAH68476.1,
AAD27959.1,
AAD54282.1,
AAC42000.1,
AAD01548.1,
AAC97962.1,
AAD54281.1,
ABY89091.1,
ABY89090.1,
ABY89092.1,
EAW81106.1,
AAD54279.1,
EAW81110.1,
EAW81103.1,
EAW81104.1,
EAW81112.1,
EAW81105.1,
EAW81113.1,
EAW81108.1,
EAW81114.1,
EAW81109.1,
EAW81100.1,
EAW81111.1
Gene_ORFName:
hCG_1811757,
hCG_1811757,
hCG_1811757,
hCG_1811757
Ensembl_TRS:
ENST00000535282,
ENST00000559312,
ENST00000554521,
ENST00000555738,
ENST00000355058,
ENST00000560335,
ENST00000555238,
ENST00000544991,
ENST00000359560,
ENST00000554546,
ENST00000356296,
ENST00000555394,
ENST00000557597
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000452416,
ENSP00000452069,
ENSP00000451625,
ENSP00000446001,
ENSP00000450817,
ENSP00000451300,
ENSP00000347169,
ENSP00000348644,
ENSP00000452888,
ENSP00000352563,
ENSP00000453209,
ENSP00000451117,
ENSP00000441258
RefSeq:
NP_001005744.1,
NP_001005743.1,
NP_001005745.1,
NP_003735.3,
NP_001307043.1
|
| Others |
UniRef100:
UniRef100_A0A024R681,
UniRef100_A0A024R684,
UniRef100_A0A024R6C4,
UniRef100_P49757
UniRef90:
UniRef90_A0A024R6C4,
UniRef90_Q9QZS3
UniRef50:
UniRef50_A1L1I3,
UniRef50_Q9QZS3
UniGene:
Hs.525443,
Hs.654609,
Hs.714879
CCDS:
CCDS32115.1,
CCDS9814.1,
CCDS55927.1,
CCDS32116.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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