| Type | Description |
|---|---|
| Definition | late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 |
| Date | Results | Publications |
|---|---|---|
| 2019-11-23 10:57:00 | LAMTOR3 is highly expressed in bladder carcinoma cell lines and tissues and plays a key role in the development and progression of bladder carcinoma. | 31699189 |
| 2018-05-19 10:28:00 | Studied role of MEK partner-1 (LAMTOR3) in driving MEK/ERK pathway in EGFRviii-expressing glioma cells. | 28830458 |
| 2017-09-30 11:12:00 | BCL2 expression in mesennchymal lung cancer cells was induced by ERK1 activity through the upregulation of the MEK1/ERK1 scaffold protein MEK partner-1. Interfering with the MEK1/MP1/ERK1 axis using a MEK1 inhibitor or MP1 depletion repressed BCL2 expression and sensitized MLCCs to chemoradiotherapy. | 28606806 |
| 2015-10-24 10:34:00 | The present study was aimed at investigating whether the miR-29c binding site single nucleotide polymorphisms within the 3'-UTRs of LAMTOR3 gene affected the gastric cancer risk. | 25661340 |
| 2013-09-28 11:49:00 | we demonstrate that the MAPK scaffold protein MEK partner 1 (MP1) is important for gastrin-induced phosphorylation of ERK1 and ERK2 and that MP1 promotes gastrin-induced proliferation of AGS-GR cells | 23408059 |
| Type | IDs |
|---|---|
| Synonymous | MAP2K1IP1, MAPBP, MAPKSP1, MP1, PRO0633, Ragulator3 |
| Gene |
UniProtKB-ID:
LTOR3_HUMAN
UniprotKB:
Q9UHA4
UniParc:
UPI0000422AC6,
UPI000012F194
EMBL:
AF201947,
CH471057,
AL544981,
BC026245,
AP001962,
AF130115,
AK311755
Ensembl:
ENSG00000109270
KO:
hsa:8649
|
| Nucleutide sequences |
EMBL-CDS:
EAX06112.1,
AAF17239.1,
AAG35540.1,
BAG34698.1,
AAH26245.1
Gene_ORFName:
PRO2783
Ensembl_TRS:
ENST00000226522,
ENST00000499666
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000424183,
ENSP00000226522
RefSeq:
NP_068805.1,
NP_001230665.1
|
| Others |
UniRef100:
UniRef100_Q9UHA4
UniRef90:
UniRef90_Q9UHA4
UniRef50:
UniRef50_Q9UHA4
UniGene:
Hs.433332
CCDS:
CCDS58920.1,
CCDS3652.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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