| Type | Description |
|---|---|
| Definition | eukaryotic translation initiation factor 4E binding protein 3 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-20 13:27:00 | eIF4EBP3 was downregulated by methylation and acted as a tumor suppressor by targeting eIF4E/beta-catenin in gastric cancer. | 31853750 |
| 2018-08-25 11:16:00 | Role of the eIF4EBP3 gene in miR-22-3p-mediated cervical squamous carcinoma cell growth | 29333098 |
| 2018-08-25 10:42:00 | The data reveal that 4E-BP3 expression is controlled by the transcription factor TFE3 through a cis-regulatory element in the EIF4EBP3 gene promoter. | 27319316 |
| 2012-10-13 11:08:00 | 4E-BP3 regulates eIF4E-mediated nuclear mRNA export and interacts with replication protein A2 | 22684010 |
| 2011-06-18 10:35:00 | potential prognostic factor for survival in patients with lung adenocarcinoma | 20621385 |
| Type | IDs |
|---|---|
| Synonymous | 4E-BP3, 4EBP3 |
| Gene |
UniProtKB-ID:
4EBP3_HUMAN
UniprotKB:
O60516
UniParc:
UPI0000073709
EMBL:
AF038869,
BC073751,
BC010881,
BC069293
Ensembl:
ENSG00000243056
KO:
hsa:8637
|
| Nucleutide sequences |
EMBL-CDS:
AAH10881.1,
AAH69293.1,
AAH73751.1,
AAC39761.1
Ensembl_TRS:
ENST00000310331
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000308472
RefSeq:
NP_003723.1
|
| Others |
UniRef100:
UniRef100_O60516
UniRef90:
UniRef90_O60516
UniRef50:
UniRef50_O60516
UniGene:
Hs.594084
CCDS:
CCDS4226.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 31853750 |
Gastric Cancer Shuting Zhai , Shuang Lin , Zhongjie Lin , Junjie Xu , Tong Ji , Ke Chen , Ke Wu , Hui Liu , Hanning Ying , Weiqiang Fei , Jin Wang , Guoxiang Fu , Yifan Wang , Xiaotong Hu , Xiujun Cai |
2020-05-01 | - |
| 32296183 |
A reference map of the human binary protein interactome. Nature Katja Luck , Dae-Kyum Kim , Luke Lambourne , Kerstin Spirohn , Bridget E Begg , Wenting Bian , Ruth Brignall , Tiziana Cafarelli , Francisco J Campos-Laborie , Benoit Charloteaux , Dongsic Choi , Atina G Coté , Meaghan Daley , Steven Deimling , Alice Desbuleux , Amélie Dricot , Marinella Gebbia , Madeleine F Hardy , Nishka Kishore , Jennifer J Knapp , István A Kovács , Irma Lemmens , Miles W Mee , Joseph C Mellor , Carl Pollis , Carles Pons , Aaron D Richardson , Sadie Schlabach , Bridget Teeking , Anupama Yadav , Mariana Babor , Dawit Balcha , Omer Basha , Christian Bowman-Colin , Suet-Feung Chin , Soon Gang Choi , Claudia Colabella , Georges Coppin , Cassandra D'Amata , David De Ridder , Steffi De Rouck , Miquel Duran-Frigola , Hanane Ennajdaoui , Florian Goebels , Liana Goehring , Anjali Gopal , Ghazal Haddad , Elodie Hatchi , Mohamed Helmy , Yves Jacob , Yoseph Kassa , Serena Landini , Roujia Li , Natascha van Lieshout , Andrew MacWilliams , Dylan Markey , Joseph N Paulson , Sudharshan Rangarajan , John Rasla , Ashyad Rayhan , Thomas Rolland , Adriana San-Miguel , Yun Shen , Dayag Sheykhkarimli , Gloria M Sheynkman , Eyal Simonovsky , Murat TaÅan , Alexander Tejeda , Vincent Tropepe , Jean-Claude Twizere , Yang Wang , Robert J Weatheritt , Jochen Weile , Yu Xia , Xinping Yang , Esti Yeger-Lotem , Quan Zhong , Patrick Aloy , Gary D Bader , Javier De Las Rivas , Suzanne Gaudet , Tong Hao , Janusz Rak , Jan Tavernier , David E Hill , Marc Vidal , Frederick P Roth , Michael A Calderwood |
2020-04-01 | - |
| 29333098 |
Int J Med Sci Kang-Tai Lv , Zhu Liu , Jie Feng , Wei Zhao , Tao Hao , Wen-Yan Ding , Jing-Ping Chu , Ling-Juan Gao |
2018-01-01 | - |
| 27319316 |
Translation control during prolonged mTORC1 inhibition mediated by 4E-BP3. Nat Commun Yoshinori Tsukumo , Tommy Alain , Bruno D Fonseca , Robert Nadon , Nahum Sonenberg |
2016-06-20 | - |
| 25416956 |
A proteome-scale map of the human interactome network. Cell Thomas Rolland , Murat TaÅan , Benoit Charloteaux , Samuel J Pevzner , Quan Zhong , Nidhi Sahni , Song Yi , Irma Lemmens , Celia Fontanillo , Roberto Mosca , Atanas Kamburov , Susan D Ghiassian , Xinping Yang , Lila Ghamsari , Dawit Balcha , Bridget E Begg , Pascal Braun , Marc Brehme , Martin P Broly , Anne-Ruxandra Carvunis , Dan Convery-Zupan , Roser Corominas , Jasmin Coulombe-Huntington , Elizabeth Dann , Matija Dreze , Amélie Dricot , Changyu Fan , Eric Franzosa , Fana Gebreab , Bryan J Gutierrez , Madeleine F Hardy , Mike Jin , Shuli Kang , Ruth Kiros , Guan Ning Lin , Katja Luck , Andrew MacWilliams , Jörg Menche , Ryan R Murray , Alexandre Palagi , Matthew M Poulin , Xavier Rambout , John Rasla , Patrick Reichert , Viviana Romero , Elien Ruyssinck , Julie M Sahalie , Annemarie Scholz , Akash A Shah , Amitabh Sharma , Yun Shen , Kerstin Spirohn , Stanley Tam , Alexander O Tejeda , Shelly A Trigg , Jean-Claude Twizere , Kerwin Vega , Jennifer Walsh , Michael E Cusick , Yu Xia , Albert-László Barabási , Lilia M Iakoucheva , Patrick Aloy , Javier De Las Rivas , Jan Tavernier , Michael A Calderwood , David E Hill , Tong Hao , Frederick P Roth , Marc Vidal |
2014-11-20 | - |
| 24722188 |
Nat Commun Roser Corominas , Xinping Yang , Guan Ning Lin , Shuli Kang , Yun Shen , Lila Ghamsari , Martin Broly , Maria Rodriguez , Stanley Tam , Shelly A Trigg , Changyu Fan , Song Yi , Murat Tasan , Irma Lemmens , Xingyan Kuang , Nan Zhao , Dheeraj Malhotra , Jacob J Michaelson , Vladimir Vacic , Michael A Calderwood , Frederick P Roth , Jan Tavernier , Steve Horvath , Kourosh Salehi-Ashtiani , Dmitry Korkin , Jonathan Sebat , David E Hill , Tong Hao , Marc Vidal , Lilia M Iakoucheva |
2014-01-01 |
ADA,
CDH9,
CDH10,
TRIM10,
SORBS3,
PSME3,
CALCOCO2,
SPRY2,
EFS,
IKZF1,
CDR2,
NDC80,
TACC3,
CDX4,
ZBTB18,
NEBL,
SPAG5,
RBCK1,
RAI2,
VAMP5,
CPLX1,
RCBTB2,
RBPMS,
MID2,
RAPGEF4,
KLF12,
EXOSC8,
DTX2,
GALNT13,
GPRASP2,
CMTM5,
AGAP1,
RAB3IP,
SSX2IP,
PIH1D2,
RHEBL1,
PRR20A,
FSD2,
ADORA2A,
FUNDC1,
PTCHD1,
CRMP1,
CRX,
NOL4L,
DYDC1,
MIPOL1,
MGAT5B,
CTBP1,
CTBP2,
TTC23L,
ADRB2,
AMOT,
ADSL,
SAXO1,
CCDC67,
DAB1,
DAO,
OTUD7A,
MARCH10,
AP2B1,
AES,
TXLNB,
FAM9B,
DHCR7,
DHPS,
SEPT1,
DLG2,
DLX1,
DLX2,
DMPK,
DPYD,
DPYSL2,
DRD3,
ABAT,
EDA,
EIF4E,
EIF4EBP1,
EIF4EBP2,
TXLNA,
ERBB2,
ESR2,
SPERT,
REEP3,
EEF1AKMT1,
RFX6,
FGFR3,
FHIT,
IKZF3,
IKZF2,
NTNG1,
ZBTB1,
FAN1,
RPIA,
SWAP70,
SEPT6,
CEP68,
CYFIP1,
GSE1,
FAM168A
|
| 23443559 |
LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells. Nat Commun Marie-Laure Fogeron , Hannah Müller , Sophia Schade , Felix Dreher , Verena Lehmann , Anne Kühnel , Anne-Kathrin Scholz , Karl Kashofer , Alexandra Zerck , Beatrix Fauler , Rudi Lurz , Ralf Herwig , Kurt Zatloukal , Hans Lehrach , Johan Gobom , Eckhard Nordhoff , Bodo M H Lange |
2013-01-01 |
HDAC5,
PDCD6,
RPS15P2,
HUWE1,
LRPPRC,
FRY,
TRAP1,
TRIM28,
CDK2,
CDK3,
ALYREF,
CDK4,
PSME3,
CDK5,
HNRNPR,
DCAF7,
CDKN1A,
DNAJA2,
CCNO,
TUBA1B,
TUBB3,
TUBB4A,
TUBB4B,
MYL12B,
TUBGCP3,
RBM14,
HAX1,
TIMM44,
TADA3,
VAT1,
FBLN5,
DDX17,
CCT7,
CCT4,
CCT2,
PRPF8,
IGF2BP1,
IGF2BP3,
SPINT2,
CCT8,
SEPT9,
SDCCAG3,
TUBGCP2,
PPP1R13L,
RUVBL2,
PNPLA6,
TCERG1,
MAGED2,
EBNA1BP2,
YWHAQ,
SF3B2,
ZWINT,
CDC37,
PSIP1,
WDR6,
CEP250,
RPL35,
RDH13,
EXOSC8,
TUBGCP5,
HAUS1,
CKS1B,
CKS2,
SSX2IP,
PARD3B,
EXOSC6,
CHCHD1,
CLCN6,
ANAPC16,
NEDD1,
TDRD9,
CCDC43,
RAVER1,
HINT3,
AMER1,
ADGRG4,
MYL6B,
TCEAL2,
RPL10L,
CSNK2A1,
CSTA,
DCST1,
RPS7P4,
CTNNA2,
CTNND1,
CTPS1,
FAM117B,
SPICE1,
RPL7AP27,
SLC2A12,
AMOT,
DGKH,
TOR1AIP2,
SDE2,
DDB1,
UBXN2A,
DDX5,
DHX9,
DHX15
|
| 22684010 |
4E-BP3 regulates eIF4E-mediated nuclear mRNA export and interacts with replication protein A2. FEBS Lett. Chao-Chung Chen , Jeng-Chang Lee , Ming-Chung Chang |
2012-07-30 |
EIF4E,
RPA2,
EIF4EBP3
|
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 21088106 |
Carcinogenesis Martha L Slattery , Abbie Lundgreen , Jennifer S Herrick , Bette J Caan , John D Potter , Roger K Wolff |
2011-03-01 |
EIF4BP2,
EIF4E,
MAPK1,
RUNX2,
RUNX1,
EIF4EBP3,
RUNX3
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
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| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
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