| Type | Description |
|---|---|
| Definition | pre-mRNA processing factor 18 |
| Date | Results | Publications |
|---|---|---|
| 2018-11-17 12:19:00 | These results validated the association of two previously known skin pigmentation genes, SLC24A5 (minimum p = 2.62 x 10(-14), rs1426654) and SLC45A2 (minimum p = 9.71 x 10(-10), rs16891982), and revealed the intergenic region of BEND7 and PRPF18 as a novel locus associated with this trait (minimum p = 4.58 x 10(-9), rs6602666). | 28300201 |
| 2017-05-20 14:03:00 | We identified the pre-mRNA processing factor Prp18 as a stimulatory factor for influenza virus RNA synthesis. Prp18 facilitates the elongation reaction of viral polymerases by preventing the deleterious annealing of newly synthesized RNA to the template. Prp18 functions as a chaperone for NP to stimulate the formation of NP-RNA complexes. | 27852861 |
| 2012-06-02 10:42:00 | Presented is solution structure of the splicing factor motif of hPrp18, which forms a compact fold with two a helices interacting head-to-tail and a fixed linker loop. | 22213562 |
| 2010-06-30 22:05:00 | Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | 20379614 |
| 2009-12-02 21:41:00 | Observational study of gene-disease association. (HuGE Navigator) | 16385451 |
| Type | IDs |
|---|---|
| Synonymous | PRP18, hPrp18 |
| Gene |
UniProtKB-ID:
PRP18_HUMAN
UniprotKB:
Q99633
UniParc:
UPI000006D3B3,
UPI0000070C82
EMBL:
CH471072,
BC002572,
BC000794,
U51990,
AL157392
Ensembl:
ENSG00000165630
KO:
hsa:8559
|
| Nucleutide sequences |
EMBL-CDS:
AAH00794.1,
AAB41490.1,
EAW86281.1
Ensembl_TRS:
ENST00000378572
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000367835
RefSeq:
XP_011518056.1,
NP_003666.1,
XP_016872349.1
|
| Others |
UniRef100:
UniRef100_Q99633
UniRef90:
UniRef90_Q99633
UniRef50:
UniRef50_Q99633
UniGene:
Hs.729158
CCDS:
CCDS7100.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 32296183 |
A reference map of the human binary protein interactome. Nature Katja Luck , Dae-Kyum Kim , Luke Lambourne , Kerstin Spirohn , Bridget E Begg , Wenting Bian , Ruth Brignall , Tiziana Cafarelli , Francisco J Campos-Laborie , Benoit Charloteaux , Dongsic Choi , Atina G Coté , Meaghan Daley , Steven Deimling , Alice Desbuleux , Amélie Dricot , Marinella Gebbia , Madeleine F Hardy , Nishka Kishore , Jennifer J Knapp , István A Kovács , Irma Lemmens , Miles W Mee , Joseph C Mellor , Carl Pollis , Carles Pons , Aaron D Richardson , Sadie Schlabach , Bridget Teeking , Anupama Yadav , Mariana Babor , Dawit Balcha , Omer Basha , Christian Bowman-Colin , Suet-Feung Chin , Soon Gang Choi , Claudia Colabella , Georges Coppin , Cassandra D'Amata , David De Ridder , Steffi De Rouck , Miquel Duran-Frigola , Hanane Ennajdaoui , Florian Goebels , Liana Goehring , Anjali Gopal , Ghazal Haddad , Elodie Hatchi , Mohamed Helmy , Yves Jacob , Yoseph Kassa , Serena Landini , Roujia Li , Natascha van Lieshout , Andrew MacWilliams , Dylan Markey , Joseph N Paulson , Sudharshan Rangarajan , John Rasla , Ashyad Rayhan , Thomas Rolland , Adriana San-Miguel , Yun Shen , Dayag Sheykhkarimli , Gloria M Sheynkman , Eyal Simonovsky , Murat TaÅan , Alexander Tejeda , Vincent Tropepe , Jean-Claude Twizere , Yang Wang , Robert J Weatheritt , Jochen Weile , Yu Xia , Xinping Yang , Esti Yeger-Lotem , Quan Zhong , Patrick Aloy , Gary D Bader , Javier De Las Rivas , Suzanne Gaudet , Tong Hao , Janusz Rak , Jan Tavernier , David E Hill , Marc Vidal , Frederick P Roth , Michael A Calderwood |
2020-04-01 | - |
| 30033366 |
Mapping the Genetic Landscape of Human Cells. Cell Max A Horlbeck , Albert Xu , Min Wang , Neal K Bennett , Chong Y Park , Derek Bogdanoff , Britt Adamson , Eric D Chow , Martin Kampmann , Tim R Peterson , Ken Nakamura , Michael A Fischbach , Jonathan S Weissman , Luke A Gilbert |
2018-08-09 | - |
| 28300201 |
Identification of a novel locus associated with skin colour in African-admixed populations. Sci Rep Natalia Hernandez-Pacheco , Carlos Flores , Santos Alonso , Celeste Eng , Angel C Y Mak , Scott Hunstman , Donglei Hu , Marquitta J White , Sam S Oh , Kelley Meade , Harold J Farber , Pedro C Avila , Denise Serebrisky , Shannon M Thyne , Emerita Brigino-Buenaventura , William Rodriguez-Cintron , Saunak Sen , Rajesh Kumar , Michael Lenoir , Jose R Rodriguez-Santana , Esteban G Burchard , Maria Pino-Yanes |
2017-03-16 | - |
| 27852861 |
J. Virol. M Minakuchi , K Sugiyama , Y Kato , T Naito , M Okuwaki , A Kawaguchi , K Nagata |
2017-02-01 | - |
| 26598620 |
PAK4 promotes kinase-independent stabilization of RhoU to modulate cell adhesion. J. Cell Biol. Anna E Dart , Gary M Box , William Court , Madeline E Gale , John P Brown , Sarah E Pinder , Suzanne A Eccles , Claire M Wells |
2015-11-23 |
PAK4,
NPM3,
SIVA1,
ATP5L,
DMRT2,
CTCF,
SLC26A1,
ME3,
RALBP1,
RASSF1,
NXPH4,
IL17F,
TMEM106A,
CHRNA4,
FCHO2,
ARHGEF25,
AP1S1,
ZFAND2B,
HINT3,
SSC4D,
RAB40A,
LAYN,
ZNF569,
BNIPL,
DACT2,
GALNTL5,
RHOV,
DNM2,
EIF4B,
ERF,
MRAS,
SEPT6,
FKBP15,
ESYT1,
LARS2,
ELP5,
IFFO1,
POT1,
ACAD8,
HCAR1,
TEKT2,
PDLIM3,
GLI3,
SEC14L4,
TRIM59,
MRPL15,
BRF1,
NRBF2,
ERO1A,
HIST1H1A,
ANXA4,
ANXA6,
BRINP3,
ID2,
CDKL4,
HSD17B13,
TMEM255B,
CFAP100,
KAAG1,
KLRC3,
LMO7,
VWA5A,
C8orf59,
RPS17P16,
ARNTL,
LYL1,
MARCKS,
MOS,
SNU13,
PAK1,
ZNF117,
ANGPT4,
PGK1,
PLEK,
ATP6AP1,
P4HTM,
C14orf119,
PRB1,
DOK4,
ZFP64,
ZKSCAN7,
LANCL2,
PCDHGA4,
PSMA4,
SEMA3G,
UTP3,
KIAA1191,
AS3MT,
USP37,
PXN,
RHOU,
RAD51D,
RPS15A,
BDNF,
S100A4,
OXCT2,
CLEC7A,
SKIV2L,
ZNF747
|
| 26496610 |
A human interactome in three quantitative dimensions organized by stoichiometries and abundances. Cell Marco Y Hein , Nina C Hubner , Ina Poser , Jürgen Cox , Nagarjuna Nagaraj , Yusuke Toyoda , Igor A Gak , Ina Weisswange , Jörg Mansfeld , Frank Buchholz , Anthony A Hyman , Matthias Mann |
2015-10-22 |
Cep85l,
Rcc1,
Zbtb48,
Bsdc1,
Kifc1,
Ccp110,
Ints4,
Slc6a8,
Cenpi,
Nup107,
Xpo1,
Fbxw11,
Tubg1,
Csnk1d,
Bap1,
Ptpn23,
Tecpr2,
Slain1,
Ankrd28,
Prkaa1,
Espl1,
Gbf1,
Cdc20,
Cenpf,
Trip11,
Mbd5,
Kif22,
Dut,
Srsf1,
Actb,
Spred2,
Akt2,
Mta1,
Tgs1,
Pip4k2c,
Ankfy1,
Apc,
Ar,
Rhoa,
Atp2a2,
Atp5a1,
Atp7a,
Cep131,
Bach1,
Bcl7c,
Bmpr1a,
Brca1,
Bub1,
Bub1b,
C1qbp,
Anxa2,
Calu,
Cbx1,
Cbx4,
Cct2,
Cct3,
Cct4,
Cct7,
Cct8,
Cd2ap,
Cdk1,
Cdc37,
Cdh1,
Chek1,
Cit,
Copa,
Crebbp,
Cry1,
Csk,
Smc3,
Dctn1,
Ddb1,
Cdk2ap1,
Mapre1,
Ect2,
Eef1a1,
Eif3a,
Mark2,
Evpl,
Ewsr1,
Wdr5,
Dclre1b,
Fbl,
Fgfr1,
Flot1,
Flot2,
B4galt1,
Gnb1,
Gspt1,
Hdac6,
Herc2,
Hsf1,
Hsph1,
Elavl1,
Id2,
Cyr61,
Cep250,
Insr,
Eif3e
|
| 26344197 |
Panorama of ancient metazoan macromolecular complexes. Nature Cuihong Wan , Blake Borgeson , Sadhna Phanse , Fan Tu , Kevin Drew , Greg Clark , Xuejian Xiong , Olga Kagan , Julian Kwan , Alexandr Bezginov , Kyle Chessman , Swati Pal , Graham Cromar , Ophelia Papoulas , Zuyao Ni , Daniel R Boutz , Snejana Stoilova , Pierre C Havugimana , Xinghua Guo , Ramy H Malty , Mihail Sarov , Jack Greenblatt , Mohan Babu , W Brent Derry , Elisabeth R Tillier , John B Wallingford , John Parkinson , Edward M Marcotte , Andrew Emili |
2015-09-17 |
AKT3,
MED6,
ABI1,
GNPDA1,
SRA1,
TDRD15,
HMGN1P30,
PDCD6IP,
PDCD6,
MED16,
ADA,
CHAF1A,
TOM1,
RANBP9,
SMC4,
ARPC4-TTLL3,
RBM14-RBM4,
RNF103-CHMP3,
CHURC1-FNTB,
AP1M2,
ISY1-RAB43,
UBA2,
SAE1,
FARSB,
DNM1L,
ABCF2,
COX17,
SCAMP2,
SCAMP3,
DPP3,
SNUPN,
HUWE1,
TSSC4,
ATP9A,
PQBP1,
COL4A3BP,
PTGES3L-AARSD1,
ARPC5,
ARPC4,
ARPC3,
ARPC1B,
ACTR3,
ACTR2,
NUBP2,
PPIF,
LOC101060521,
ARPC2,
RAD50,
ACTR1B,
ACTR1A,
ADAM8,
LRPPRC,
PDIA6,
TRAP1,
BCAP31,
NAMPT,
RBM12,
G3BP1,
ABI2,
CEBPZ,
TRIM28,
AASS,
ATP6AP2,
WASF2,
SLC25A13,
CDK2,
RBM7,
ALYREF,
TXNDC9,
LOC101929876,
PSME3,
MPHOSPH10,
MPHOSPH6,
CDK5,
NUTF2,
EIF1,
DDX39A,
PSMD14,
CDK7,
PLIN3,
HNRNPR,
MRPS31,
CDK8,
RABEPK,
RIDA,
SRRM1,
CDK9,
STAM2,
SF3B4,
ZMPSTE24,
AKAP8,
STUB1,
STAG1,
UBE4B,
PRSS16,
SIGMAR1,
BET1,
CWC27,
SAP18
|
| 24925725 |
Lupus nephritis susceptibility loci in women with systemic lupus erythematosus. J. Am. Soc. Nephrol. Sharon A Chung , Elizabeth E Brown , Adrienne H Williams , Paula S Ramos , Celine C Berthier , Tushar Bhangale , Marta E Alarcon-Riquelme , Timothy W Behrens , Lindsey A Criswell , Deborah Cunninghame Graham , F Yesim Demirci , Jeffrey C Edberg , Patrick M Gaffney , John B Harley , Chaim O Jacob , M Ilyas Kamboh , Jennifer A Kelly , Susan Manzi , Kathy L Moser-Sivils , Laurie P Russell , Michelle Petri , Betty P Tsao , Tim J Vyse , Raphael Zidovetzki , Matthias Kretzler , Robert P Kimberly , Barry I Freedman , Robert R Graham , Carl D Langefeld , International Consortium for Systemic Lupus Erythematosus Genetics |
2014-12-01 | - |
| 24025145 |
A genome-wide association study of chemotherapy-induced alopecia in breast cancer patients. Breast Cancer Res Suyoun Chung , Siew-Kee Low , Hitoshi Zembutsu , Atsushi Takahashi , Michiaki Kubo , Mitsunori Sasa , Yusuke Nakamura |
2013-01-01 | - |
| 22939629 |
A census of human soluble protein complexes. Cell Pierre C Havugimana , G Traver Hart , Tamás Nepusz , Haixuan Yang , Andrei L Turinsky , Zhihua Li , Peggy I Wang , Daniel R Boutz , Vincent Fong , Sadhna Phanse , Mohan Babu , Stephanie A Craig , Pingzhao Hu , Cuihong Wan , James Vlasblom , Vaqaar-un-Nisa Dar , Alexandr Bezginov , Gregory W Clark , Gabriel C Wu , Shoshana J Wodak , Elisabeth R M Tillier , Alberto Paccanaro , Edward M Marcotte , Andrew Emili |
2012-08-31 |
SRB2,
TRA1,
MED6,
CDH2,
DDTL,
ABI1,
SRA1,
UQCRFS1P1,
SNRPGP15,
ZNF316,
LOC100132057,
PDCD6IP,
PDCD6,
MED16,
PIGK,
WASH1,
CHAF1A,
TOM1L1,
HMGXB4,
RANBP9,
SMC4,
UBA2,
SAE1,
FARSB,
ABCB6,
ABCF2,
TIMM23B,
SCAMP3,
DPP3,
HUWE1,
TSSC4,
PDCD7,
USH1C,
PQBP1,
ARPC5,
ARPC4,
ARPC3,
ARPC1B,
ACTR3,
ACTR2,
NUBP2,
TSFM,
PPIF,
ARPC2,
RAD50,
PREB,
ACTR1B,
ACTR1A,
RASGRP1,
LRPPRC,
PDIA6,
TRAP1,
RBM12,
G3BP1,
SUGP2,
TRIM28,
WASF2,
SLC25A13,
SORBS3,
ALYREF,
TXNDC9,
CDK4,
PRMT3,
PSME3,
MPHOSPH6,
CDK5,
NUTF2,
EIF1,
FLOT1,
PSMD14,
CDK7,
ADAM10,
PLIN3,
STX6,
MSLN,
HNRNPR,
MRPS31,
TIMM17B,
RIDA,
POP7,
SRRM1,
CDK9,
STAM2,
SF3B4,
ZMPSTE24,
STUB1,
UBE4B,
BET1,
CWC27,
SAP18,
SMNDC1,
BCAS2,
EIF1B,
SF3A1,
MAEA,
KATNB1,
TCIRG1,
RTN3,
LANCL1
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
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目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
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目前还没有研究热点人员