| Type | Description |
|---|---|
| Definition | DEAH-box RNA-dependent ATPase PRP2 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-20 13:31:00 | Mechanism of spliceosome remodeling by the ATPase/helicase Prp2 and its coactivator Spp2. | 33243853 |
| 2020-05-30 13:23:00 | The structural analysis unveils the role of conserved residues of the G-patch in the dynamic interaction mode of Spp2 with Prp2, which is vital to maintain the binding during the Prp2 domain movements needed for RNA translocation. | 31974312 |
| 2015-02-28 13:05:00 | Spp2 plays a major role in coupling Prp2's ATPase activity to remodeling of the spliceosome into a catalytically active machine | 25561498 |
| 2013-03-09 10:25:00 | NTR complex catalyzes the disassembly of affinity-purified spliceosomes arrested specifically after the ATP-dependent action of DEAH-box Prp2, Prp16, or Prp22 but not at steps before the action of these ATPases or upon their binding to the spliceosome. | 23166295 |
| 2013-02-16 12:06:00 | propose that Prp2 is recruited to the spliceosome via interaction with Brr2 and is spatially positioned to interact with this specific region of the pre-mRNA, which stimulates the ATPase activity of Prp2 to promote progression of the first catalytic step | 23071087 |
| Type | IDs |
|---|---|
| Synonymous | RNA2 |
| Gene |
UniProtKB-ID:
PRP2_YEAST
UniprotKB:
P20095
UniParc:
UPI00000531F7
EMBL:
X55936,
BK006947,
X77395,
X55999,
Z71626
EnsemblGenome:
YNR011C
KO:
sce:YNR011C
|
| Nucleutide sequences |
EMBL-CDS:
CAA54579.1,
CAA39471.1,
CAA39401.1,
DAA10552.1,
CAA96288.1
Gene_ORFName:
N2048
EnsemblGenome_TRS:
YNR011C_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YNR011C
RefSeq:
NP_014408.1
|
| Others |
UniRef100:
UniRef100_P20095
UniRef90:
UniRef90_P20095
UniRef50:
UniRef50_P20095
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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