| Type | Description |
|---|---|
| Definition | Hsp90 cochaperone STI1 |
| Date | Results | Publications |
|---|---|---|
| 2020-12-12 13:30:00 | The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation. | 33239621 |
| 2018-10-13 10:30:00 | Data suggest that Sti1 regulates Hsp90 to coordinate transfer of clients from Hsp70 with advancement of the Hsp90 cycle. Binding of Sti1 to Hsp90 both prevents commitment to subsequent steps until a productive interaction with Hsp70- delivered clients has occurred and positions Hsp90 to advance in its cycle promptly after client delivery. | 29930177 |
| 2017-07-01 12:33:00 | Using a presequence-containing model protein and a site-directed photo-crosslinking approach, we identified the cytosolic chaperones Hsp70 (Ssa1) and Hsp90 (Hsp82) as well as their cochaperones, Sti1 and Ydj1, as putative cytosolic factors involved in mitochondrial protein import. | 27412066 |
| 2016-04-09 10:28:00 | Sti1 is a dynamic, elongated protein that consists of a flexible N-terminal module, a long linker and a rigid C-terminal module. Binding of Hsp90 and Hsp70 regulates the Sti1 conformation. | 25851214 |
| 2010-07-19 12:12:00 | findings point to crucial roles of Hsp70, Sti1, and Hsp90 for efficient curing by overexpressed Hsp104 and provide evidence supporting the earlier suggestion that destruction of prions by protein disaggregation does not adequately explain the curing | 20479121 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
STI1_YEAST
UniprotKB:
P15705
UniParc:
UPI0000036C96
EMBL:
X87331,
M28486,
BK006948,
Z74935
EnsemblGenome:
YOR027W
KO:
sce:YOR027W
|
| Nucleutide sequences |
EMBL-CDS:
CAA99217.1,
AAA35121.1,
DAA10809.1,
CAA60743.1
Gene_ORFName:
OR26.17
EnsemblGenome_TRS:
YOR027W_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YOR027W
RefSeq:
NP_014670.1
|
| Others |
UniRef100:
UniRef100_P15705
UniRef90:
UniRef90_P15705
UniRef50:
UniRef50_P15705
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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