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853954 TRZ1

853954

TRZ1

tRNase Z

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition tRNase Z

研究结论

Date Results Publications
2017-10-07 12:21:00 The 3.1 A crystal structure of the long-form Trz1 from Saccharomyces cerevisiae shows Trz1 is organized into 2 beta-lactamase domains connected by a long linker. The N-terminal domain has lost its catalytic residues, but keeps the long flexible arm important for tRNA binding, but it is the opposite in the C-terminal domain. Trz1 likely evolved from a duplication and fusion of the gene for the monomeric short form RNase Z. 28379452
2014-03-01 12:29:00 The yeast tRNA 3' endonuclease tRNase Z, Trz1, is catalyzing endonucleolytic tRNA 3' processing. 24249226
2010-01-21 00:00:00 The findings reveal that 3' end processing is a limiting step for defective tRNA maturation and demonstrate that overexpression of scTRZ1 can promote defective tRNA 3' processing in vivo. 19555350
2010-01-21 00:00:00 AthTRZ1 shows a high affinity for Zn2+ ions 18052196
2010-01-21 00:00:00 In this work, we show that the yeast homolog of ELAC2, encoded by TRZ1 (tRNase Z 1), is involved genetically in RNA processing. 15892892

名称对应

Type IDs
Gene
UniProtKB-ID: RNZ_YEAST
UniprotKB: P36159
UniParc: UPI0000052ED3
EMBL: Z28304, BK006944
EnsemblGenome: YKR079C
KO: sce:YKR079C
Nucleutide sequences
EMBL-CDS: DAA09229.1, CAA82158.1
EnsemblGenome_TRS: YKR079C_mRNA
Protein sequencees
EnsemblGenome_PRO: YKR079C
RefSeq: NP_013005.1
Others
UniRef100: UniRef100_P36159
UniRef90: UniRef90_P36159
UniRef50: UniRef50_P36159

全选

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研究热度

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