| Type | Description |
|---|---|
| Definition | apoptosis inhibitor 5 |
| Date | Results | Publications |
|---|---|---|
| 2020-09-12 16:05:00 | Regulation of mRNA export through API5 and nuclear FGF2 interaction. | 32383752 |
| 2018-01-27 10:43:00 | study demonstrates that apoptosis inhibitor 5 is an endogenous and direct inhibitor of caspase-2. API5 protein directly binds to the caspase recruitment domain (CARD) of caspase-2 and impedes dimerization and activation of caspase-2. | 28336776 |
| 2016-09-17 12:07:00 | Authors propose a proapoptotic role for NP in IAV pathogenesis, whereby it suppresses expression of antiapoptotic factor API5, thus potentiating the E2F1-dependent apoptotic pathway and ensuring viral replication. | 26673663 |
| 2016-04-23 10:27:00 | Authors show that API5 increases the metastatic capacity of cervical cancer cells in vitro and in vivo via up-regulation of MMP-9. | 25248562 |
| 2016-03-12 10:18:00 | rs17684886 (ZNRF1) and rs599019 (COLEC12) are associated with diabetic retinopathy and rs6427247 (SCYL1BP1) and rs899036 (API5) are associated with severe diabetic retinopathy in Chinese patients with type 2 diabetes | 25819896 |
| Type | IDs |
|---|---|
| Synonymous | AAC-11, AAC11 |
| Gene |
UniProtKB-ID:
API5_HUMAN,
B4DDR3_HUMAN
UniprotKB:
Q9BZZ5,
B4DDR3
UniParc:
UPI00017A6D8A,
UPI0002292FAC,
UPI00017A6E14,
UPI0002292FAD,
UPI0000E229DE,
UPI000007086D,
UPI00017A869F
EMBL:
BC017709,
CH471064,
Y15906,
AY311389,
AC087276,
U83857,
AF229253,
BT007093,
AY265973,
AK293303,
AK304157,
AF229254,
AK294724,
AK299288,
W40304
Ensembl:
ENSG00000166181
KO:
hsa:8539
|
| Nucleutide sequences |
EMBL-CDS:
AAO89077.1,
AAH17709.1,
BAG65045.1,
BAG57871.1,
AAK00738.1,
AAB86528.1,
BAG61304.1,
EAW68098.1,
AAP35756.1,
EAW68099.1,
CAA75867.1,
AAK00737.1,
AAQ76714.1,
BAG56824.1
Gene_ORFName:
MIG8
Ensembl_TRS:
ENST00000420461,
ENST00000378852,
ENST00000531273,
ENST00000455725
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000431391,
ENSP00000399341,
ENSP00000402540,
ENSP00000368129
RefSeq:
XP_016873953.1,
XP_016873954.1,
NP_001136403.1,
NP_001230676.1,
NP_001136402.1,
NP_006586.1,
XP_006718422.1
|
| Others |
UniRef100:
UniRef100_B4DDR3,
UniRef100_Q9BZZ5
UniRef90:
UniRef90_A0A340X2U9,
UniRef90_Q9BZZ5
UniRef50:
UniRef50_A0A340X2U9,
UniRef50_Q9BZZ5
UniGene:
Hs.435771
CCDS:
CCDS31465.1,
CCDS44572.1,
CCDS44573.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员