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853422 MAD2

853422

MAD2

spindle checkpoint protein MAD2

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition spindle checkpoint protein MAD2

研究结论

Date Results Publications
2019-07-13 11:34:00 Data show that Hop1 protein possesses conformational dynamics similar to spindle checkpoint protein MAD2 (Mad2), and identify closure motifs in the Hop1 binding partner Red1 protein. 29186573
2017-12-09 11:15:00 Mad2 recruitment to the kinetochore and it's role in the spindle assembly checkpoint 27280788
2013-05-04 11:34:00 the very same dimerization interface of Mad2 is required for two different, yet fundamental, consecutive steps of SAC signaling: at the kinetochores for priming Cdc20/Mad2 binding, away from kinetochores for stabilizing this complex 23000150
2012-08-11 11:27:00 Mad3 is required for the stable binding of Mad2 to Cdc20 in vivo, which is sufficient to inhibit APC activity and is the most downstream event in spindle checkpoint activation. 22209528
2011-12-10 11:19:00 Mad2 is an important meiotic cell cycle regulator that ensures the timely degradation of anaphase-promoting complex substrates and the proper orchestration of the meiotic divisions 21697504

名称对应

Type IDs
Gene
UniProtKB-ID: MAD2_YEAST
UniprotKB: P40958
UniParc: UPI000012EB17
EMBL: BK006943, U14132, Z49305, AY558243
EnsemblGenome: YJL030W
KO: sce:YJL030W
Nucleutide sequences
EMBL-CDS: AAA21385.1, DAA08768.1, CAA89321.1, AAS56569.1
Gene_ORFName: J1256
EnsemblGenome_TRS: YJL030W_mRNA
Protein sequencees
EnsemblGenome_PRO: YJL030W
RefSeq: NP_012504.3
Others
UniRef100: UniRef100_P40958
UniRef90: UniRef90_P40958
UniRef50: UniRef50_P40958

全选

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研究热度

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