| Type | Description |
|---|---|
| Definition | DEAH-box ATP-dependent RNA helicase PRP43 |
| Date | Results | Publications |
|---|---|---|
| 2017-12-02 10:58:00 | These data indicate that the U2 snRNP-intron interaction is Prp43's major target. | 27115347 |
| 2017-11-04 11:11:00 | Using Prp43 F357A mutants or pyrimidine nucleotides, we show that the lack of stacking of the nucleotide base to the F-motif decouples the NTPase and helicase activities of Prp43. In contrast the R159A mutant (R-motif) showed reduced ATPase and helicase activities. | 28180308 |
| 2017-09-23 11:38:00 | Study shows the crystal structure of Prp43p bound to single-stranded poly-uracil RNA and reveals differences with viral ATPases in the RecA1 domain but with striking similarities with viral ATPases in the RecA2 domain of the catalytic core, including both a prominent beta-hairpin that bookends the 5' end of the RNA stack and a dynamic motif Va that is implicated in mediating translocation. | 28416566 |
| 2017-08-26 12:42:00 | Ntr1 and Ntr2 may act as 'doorkeepers' and both cofactors may inspect the RNP structure of spliceosomal complexes thereby targeting suboptimal spliceosomes for Prp43-mediated disassembly. | 27923990 |
| 2016-12-17 11:22:00 | Results show that Prp43 expression is regulated by Cmg1 which stimulates its RNA helicase activity. | 26821976 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
PRP43_YEAST
UniprotKB:
P53131
UniParc:
UPI0000052F7C
EMBL:
BK006941,
Z72642,
U41851
EnsemblGenome:
YGL120C
KO:
sce:YGL120C
|
| Nucleutide sequences |
EMBL-CDS:
DAA07989.1,
CAA96828.1,
AAB86458.1
EnsemblGenome_TRS:
YGL120C_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YGL120C
RefSeq:
NP_011395.1
|
| Others |
UniRef100:
UniRef100_P53131
UniRef90:
UniRef90_P53131
UniRef50:
UniRef50_P53131
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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