| Type | Description |
|---|---|
| Definition | serine/threonine protein kinase CHK1 |
| Date | Results | Publications |
|---|---|---|
| 2015-09-05 11:51:00 | Chk1 has a redundant role in the control of DIC or that DIC is redundant for maintaining genome stability | 25551702 |
| 2013-06-29 11:28:00 | We suggest a novel model for Chk1 activation where Cdc28 regulates the constitutive interaction of Rad9 and Chk1. The Rad9/Chk1 complex is then recruited at sites of DNA damage where activation of Chk1 requires additional DDR-specific protein kinases. | 23593009 |
| 2010-01-21 00:00:00 | CHK1 mutants are not defective in double-strand break repair-initiated sister chromatid exchange, after exposure to DNA damaging agents. | 16039914 |
| 2010-01-21 00:00:00 | Chk1-Pds1 checkpoint has roles in preventing tolerance of persistent single-strand breaks in Saccharomyces cerevisiae | 15687272 |
| 2010-01-21 00:00:00 | a single amino acid substitution in the C terminus, which could lead to an allosteric change in Chk1, allows it to bypass the requirement of the conserved ATR(Mec1) phosphorylation sites for checkpoint function. | 18984588 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
CHK1_YEAST
UniprotKB:
P38147
UniParc:
UPI0000127836
EMBL:
AF117345,
Z36143,
BK006936
EnsemblGenome:
YBR274W
KO:
sce:YBR274W
|
| Nucleutide sequences |
EMBL-CDS:
DAA07390.1,
AAD17231.1,
CAA85237.1
Gene_ORFName:
YBR1742
EnsemblGenome_TRS:
YBR274W_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YBR274W
RefSeq:
NP_009833.1
|
| Others |
UniRef100:
UniRef100_P38147
UniRef90:
UniRef90_P38147
UniRef50:
UniRef50_P38147
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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