| Type | Description |
|---|---|
| Definition | DEAD-box RNA helicase PRP5 |
| Date | Results | Publications |
|---|---|---|
| 2020-09-12 16:05:00 | Prp5-Spt8/Spt3 interaction mediates a reciprocal coupling between splicing and transcription. | 32399566 |
| 2017-09-16 10:21:00 | different HSH155 alleles elicit disparate effects on splicing: some increase the fidelity of BS selection while others decrease fidelity. Our data support a model wherein conformational changes in SF3b1 promote U2 association with the BS independently of the action of the DEAD-box ATPase Prp5. We propose that SF3b1 functions to stabilize weak U2/BS duplexes to drive spliceosome assembly and splicing | 28062854 |
| 2016-07-30 11:41:00 | Taken together, our results indicate that the Psis in U2 snRNA contribute to pre-mRNA splicing by directly altering the binding/ATPase activity of Prp5. | 26873591 |
| 2015-02-28 13:05:00 | Prp5 binds to the spliceosome in association with U2 by interacting with the BSL and is released upon the base-pairing of U2 with the branch site to allow the recruitment of the tri-snRNP. | 25561497 |
| Type | IDs |
|---|---|
| Synonymous | RNA5 |
| Gene |
UniProtKB-ID:
PRP5_YEAST
UniprotKB:
P21372
UniParc:
UPI000013213C
EMBL:
BK006936,
Z36106,
AY692817,
M33191
EnsemblGenome:
YBR237W
KO:
sce:YBR237W
|
| Nucleutide sequences |
EMBL-CDS:
AAA34914.1,
AAT92836.1,
DAA07353.1,
CAA85200.1
Gene_ORFName:
YBR1603
EnsemblGenome_TRS:
YBR237W_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YBR237W
RefSeq:
NP_009796.1
|
| Others |
UniRef100:
UniRef100_P21372
UniRef90:
UniRef90_P21372
UniRef50:
UniRef50_P21372
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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