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852311 CHS3

852311

CHS3

chitin synthase CHS3

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition chitin synthase CHS3

研究结论

Date Results Publications
2019-03-23 11:10:00 We analyzed the dynamic localization and interaction of Chs3 and Chs4 during cell division, and found that both proteins transiently co-localize and physically interact only during bud formation and later in a period during septum formation and cytokinesis 29763674
2019-01-05 10:08:00 that Chs7 engages in functionally distinct interactions with Chs3 to first promote its folding and endoplasmic reticulum exit, and subsequently to regulate its activity at the plasma membrane 29405545
2018-07-28 10:21:00 Hof1 binds to the Sel1-like repeats (SLRs) of Chs4 via its F-BAR domain and inhibits Chs3-mediated chitin synthesis during cytokinesis. In addition, Hof1 is required for rapid accumulation as well as efficient removal of Chs4 at the division site. 28918945
2018-07-21 10:23:00 Synthesis of chitin by Chs3, the chitin synthase responsible for chitosan layer formation, is dependent on the cis-prenyltransferase activity of Srt1, indicating that polyprenols are necessary to coordinate assembly of the spore wall layers. 28978675
2017-03-25 10:20:00 the mitotic spindle breakage observed in endocytosis mutants can be rescued either by deleting or inhibiting the activities of, CHS2, CHS3 and FKS1, which are involved in septum formation. The findings from our study highlight the importance of timely endocytosis of cytokinetic enzymes at the division site in safeguarding mitotic spindle integrity during mitotic exit. 27447488

名称对应

Type IDs
Synonymous CAL1, CSD2, DIT101, KTI2
Gene
UniProtKB-ID: CHS3_YEAST
UniprotKB: P29465
UniParc: UPI0000127918
EMBL: X76078, M73697, Z35892, BK006936, X57300
EnsemblGenome: YBR023C
KO: sce:YBR023C
Nucleutide sequences
EMBL-CDS: AAA34844.1, CAA40559.1, CAA53680.1, DAA07145.1, CAA84965.1
Gene_ORFName: YBR0305
EnsemblGenome_TRS: YBR023C_mRNA
Protein sequencees
EnsemblGenome_PRO: YBR023C
RefSeq: NP_009579.1
Others
UniRef100: UniRef100_P29465
UniRef90: UniRef90_P29465
UniRef50: UniRef50_P29465

全选

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