| Type | Description |
|---|---|
| Definition | U2-type spliceosomal complex subunit CWC24 |
| Date | Results | Publications |
|---|---|---|
| 2019-12-14 12:04:00 | Deletion of the ZF domain or mutation of the conserved ZF residues greatly weakened the association of Cwc24 with the spliceosome, and lowered the affinity and specificity of its interaction with the 5' splice site, resulting in atypical interactions of U5, U6 and Prp8 with the 5' splice site, and aberrant cleavage at the 5' splice site | 31504764 |
| 2013-03-30 13:09:00 | propose a model in which Cwc24p is required for stabilizing the U2 association with primary transcripts, and therefore, especially important for splicing of RNAs containing non-consensus branchpoint sequences | 23029180 |
| 2010-01-21 00:00:00 | Cwc24p localizes to the cell nucleus, and its depletion leads to the accumulation of both U3 pre-snoRNAs. | 17974558 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
CWC24_YEAST
UniprotKB:
P53769
UniParc:
UPI000013B7A9
EMBL:
U20618,
BK006945
EnsemblGenome:
YLR323C
KO:
sce:YLR323C
|
| Nucleutide sequences |
EMBL-CDS:
AAB64511.1,
DAA09631.1
Gene_ORFName:
L8543.3
EnsemblGenome_TRS:
YLR323C_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YLR323C
RefSeq:
NP_013427.1
|
| Others |
UniRef100:
UniRef100_P53769
UniRef90:
UniRef90_P53769
UniRef50:
UniRef50_P53769
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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