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84915 FAM222A

84915

FAM222A

family with sequence similarity 222 member A

protein-coding

Homo sapiens

基因描述

Type Description
Definition family with sequence similarity 222 member A

研究结论

Date Results Publications
2020-05-16 10:22:00 Study reports FAM222A as a putative brain atrophy susceptibility gene. The protein encoded by FAM222A is predominantly expressed in the CNS and is increased in brains of patients with Alzheimer's disease (AD) and in an AD mouse model. It accumulates within amyloid deposits, physically interacts with amyloid-beta (Abeta) via its N-terminal Abeta binding domain and facilitates Abeta aggregation. 31964863

名称对应

Type IDs
Synonymous C12orf34
Gene
UniProtKB-ID: F222A_HUMAN, A0A024RBN3_HUMAN
UniprotKB: Q5U5X8, A0A024RBN3
UniParc: UPI000013D712
EMBL: AK027627, CH471054, BC037221, AK074806, AC007834
Ensembl: ENSG00000139438
KO: hsa:84915
Nucleutide sequences
EMBL-CDS: BAC11219.1, BAB55244.1, AAH37221.1, EAW97875.1, EAW97874.1
Gene_ORFName: hCG_1644503
Ensembl_TRS: ENST00000358906, ENST00000538780
Protein sequencees
Ensembl_PRO: ENSP00000443292, ENSP00000351783
RefSeq: XP_006719717.1, XP_016875544.1, XP_024304997.1, NP_116218.2
Others
UniRef100: UniRef100_Q5U5X8
UniRef90: UniRef90_Q5U5X8
UniRef50: UniRef50_Q5U5X8
UniGene: Hs.661785
CCDS: CCDS9133.1

全选

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研究热度

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