| Type | Description |
|---|---|
| Definition | late cornified envelope 3D |
| Date | Results | Publications |
|---|---|---|
| 2018-10-13 12:09:00 | genetic polymorphism is associated with psoriasis vulgaris among Mongolians from Inner Mongolia | 29397434 |
| 2011-06-18 11:08:00 | We identified significant combined effects between MHC and LCE, MHC and IL12B on the risk of psoriasis in Chinese population. | 21208785 |
| 2009-02-11 21:30:00 | Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) | 19169255 |
| 2005-07-12 14:21:00 | paper describing nomenclature changes and expression in range of tissues and in response to UV | 15854049 |
| 2001-11-17 14:59:00 | LEP16 is one of a cluster of 16-20 related genes at 1q21 which includes XP5. Proteins incorporate into the cornified envelope of stratified, terminally differentiating epithelia. LEP16 transcripts detected in heart, skin and esophagus. | 11698679 |
| Type | IDs |
|---|---|
| Synonymous | LEP16, SPRL6A, SPRL6B |
| Gene |
UniProtKB-ID:
LCE3D_HUMAN
UniprotKB:
Q9BYE3
UniParc:
UPI000006EC48
EMBL:
AB048288,
BC069291,
AL356426,
BC101784
Ensembl:
ENSG00000163202
KO:
hsa:84648
|
| Nucleutide sequences |
EMBL-CDS:
BAB40643.1,
AAH69291.1,
AAI01785.1
Ensembl_TRS:
ENST00000368787
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000357776
RefSeq:
NP_115952.1
|
| Others |
UniRef100:
UniRef100_Q9BYE3
UniRef90:
UniRef90_Q9BYE3
UniRef50:
UniRef50_Q5TA76
UniGene:
Hs.244349
CCDS:
CCDS1014.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 32296183 |
A reference map of the human binary protein interactome. Nature Katja Luck , Dae-Kyum Kim , Luke Lambourne , Kerstin Spirohn , Bridget E Begg , Wenting Bian , Ruth Brignall , Tiziana Cafarelli , Francisco J Campos-Laborie , Benoit Charloteaux , Dongsic Choi , Atina G Coté , Meaghan Daley , Steven Deimling , Alice Desbuleux , Amélie Dricot , Marinella Gebbia , Madeleine F Hardy , Nishka Kishore , Jennifer J Knapp , István A Kovács , Irma Lemmens , Miles W Mee , Joseph C Mellor , Carl Pollis , Carles Pons , Aaron D Richardson , Sadie Schlabach , Bridget Teeking , Anupama Yadav , Mariana Babor , Dawit Balcha , Omer Basha , Christian Bowman-Colin , Suet-Feung Chin , Soon Gang Choi , Claudia Colabella , Georges Coppin , Cassandra D'Amata , David De Ridder , Steffi De Rouck , Miquel Duran-Frigola , Hanane Ennajdaoui , Florian Goebels , Liana Goehring , Anjali Gopal , Ghazal Haddad , Elodie Hatchi , Mohamed Helmy , Yves Jacob , Yoseph Kassa , Serena Landini , Roujia Li , Natascha van Lieshout , Andrew MacWilliams , Dylan Markey , Joseph N Paulson , Sudharshan Rangarajan , John Rasla , Ashyad Rayhan , Thomas Rolland , Adriana San-Miguel , Yun Shen , Dayag Sheykhkarimli , Gloria M Sheynkman , Eyal Simonovsky , Murat TaÅan , Alexander Tejeda , Vincent Tropepe , Jean-Claude Twizere , Yang Wang , Robert J Weatheritt , Jochen Weile , Yu Xia , Xinping Yang , Esti Yeger-Lotem , Quan Zhong , Patrick Aloy , Gary D Bader , Javier De Las Rivas , Suzanne Gaudet , Tong Hao , Janusz Rak , Jan Tavernier , David E Hill , Marc Vidal , Frederick P Roth , Michael A Calderwood |
2020-04-01 | - |
| 29397434 |
Arch. Dermatol. Res. Li Sun , Yuting Cao , Nagonbilig He , Jianwen Han , Rong Hai , Sarnai Arlud , Baoyindeligeer He , Wurina Wu , Lizhong Li , Xiulan Su , Hongwei Cui , Wenchao Zhao , Buheqiqige Chao , Dandan Liu , Zhiqiang Sun , Yanping Huang |
2018-05-01 | - |
| 23602568 |
The protein interaction landscape of the human CMGC kinase group. Cell Rep Markku Varjosalo , Salla Keskitalo , Audrey Van Drogen , Helka Nurkkala , Anton Vichalkovski , Ruedi Aebersold , Matthias Gstaiger |
2013-04-25 |
MED6,
PDCD6IP,
FRAT1,
TROAP,
MED16,
RWDD2B,
HUWE1,
EDIL3,
ARPC1B,
HIPK3,
FRY,
AKAP9,
SUGP2,
RASA4,
CDK2,
RBM7,
CDK3,
CDK4,
PSME3,
CDK5,
FLOT1,
DDX39A,
CDK6,
CDK7,
HNRNPR,
DCAF7,
CDK8,
SRRM1,
CDK9,
SF3B4,
CDKN1A,
AKAP8,
CDKN1B,
STUB1,
CDKN1C,
CDKN2A,
PAK4,
CDKN2B,
ZNF267,
CDKN2C,
CDKN2D,
NPM2,
CACNG2,
RBM14,
HAX1,
BAIAP2,
PFDN6,
EIF3M,
SEC23B,
ENOX2,
MYBBP1A,
CHERP,
NOP56,
UBD,
MAB21L2,
DRAP1,
PRPF8,
CDC42EP3,
USP39,
PTGES3,
YME1L1,
NUP50,
HBS1L,
AHCYL1,
ZMYND11,
ZNF460,
CPSF4,
TRAFD1,
MAGED2,
RNPS1,
SUB1,
SRSF8,
AFG3L2,
MSL3,
STIP1,
EBNA1BP2,
SNRNP27,
STON1,
NUDT21,
CPSF6,
CHD2,
SNRNP35,
DIDO1,
WDR5,
KRR1,
FOXN3,
CLASRP,
KPTN,
WDR6,
SUPT16H,
CHEK2,
AKAP11,
EGLN2,
MED8,
GLCCI1,
GABARAP,
U2AF2,
CHUK,
EVI5L
|
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 21208785 |
Variants in MHC, LCE and IL12B have epistatic effects on psoriasis risk in Chinese population. J. Dermatol. Sci. Hou-Feng Zheng , Xian-Bo Zuo , Wen-Sheng Lu , Yang Li , Hui Cheng , Kun-Ju Zhu , Xian-Yong Yin , Chi Zhang , Yun-Qing Ren , Wen-Ju Wang , Liang-Dan Sun , Yong Cui , Sen Yang , Feng-Yu Zhang , Xue-Jun Zhang |
2011-02-01 |
HLA-E,
IL12B,
LCE3D
|
| 20953190 |
Nat Genet Genetic Analysis of Psoriasis Consortium & the Wellcome Trust Case Control Consortium 2 , Amy Strange , Francesca Capon , Chris C A Spencer , Jo Knight , Michael E Weale , Michael H Allen , Anne Barton , Gavin Band , Céline Bellenguez , Judith G M Bergboer , Jenefer M Blackwell , Elvira Bramon , Suzannah J Bumpstead , Juan P Casas , Michael J Cork , Aiden Corvin , Panos Deloukas , Alexander Dilthey , Audrey Duncanson , Sarah Edkins , Xavier Estivill , Oliver Fitzgerald , Colin Freeman , Emiliano Giardina , Emma Gray , Angelika Hofer , Ulrike Hüffmeier , Sarah E Hunt , Alan D Irvine , Janusz Jankowski , Brian Kirby , Cordelia Langford , Jesús Lascorz , Joyce Leman , Stephen Leslie , Lotus Mallbris , Hugh S Markus , Christopher G Mathew , W H Irwin McLean , Ross McManus , Rotraut Mössner , Loukas Moutsianas , Asa T Naluai , Frank O Nestle , Giuseppe Novelli , Alexandros Onoufriadis , Colin N A Palmer , Carlo Perricone , Matti Pirinen , Robert Plomin , Simon C Potter , Ramon M Pujol , Anna Rautanen , Eva Riveira-Munoz , Anthony W Ryan , Wolfgang Salmhofer , Lena Samuelsson , Stephen J Sawcer , Joost Schalkwijk , Catherine H Smith , Mona Ståhle , Zhan Su , Rachid Tazi-Ahnini , Heiko Traupe , Ananth C Viswanathan , Richard B Warren , Wolfgang Weger , Katarina Wolk , Nicholas Wood , Jane Worthington , Helen S Young , Patrick L J M Zeeuwen , Adrian Hayday , A David Burden , Christopher E M Griffiths , Juha Kere , André Reis , Gilean McVean , David M Evans , Matthew A Brown , Jonathan N Barker , Leena Peltonen , Peter Donnelly , Richard C Trembath |
2010-11-01 | - |
| 19169255 |
Nat Genet Xue-Jun Zhang , Wei Huang , Sen Yang , Liang-Dan Sun , Feng-Yu Zhang , Qi-Xing Zhu , Fu-Ren Zhang , Chi Zhang , Wen-Hui Du , Xiong-Ming Pu , Hui Li , Feng-Li Xiao , Zai-Xing Wang , Yong Cui , Fei Hao , Jie Zheng , Xue-Qin Yang , Hui Cheng , Chun-Di He , Xiao-Ming Liu , Li-Min Xu , Hou-Feng Zheng , Shu-Mei Zhang , Jian-Zhong Zhang , Hong-Yan Wang , Yi-Lin Cheng , Bi-Hua Ji , Qiao-Yun Fang , Yu-Zhen Li , Fu-Sheng Zhou , Jian-Wen Han , Cheng Quan , Bin Chen , Jun-Lin Liu , Da Lin , Li Fan , An-Ping Zhang , Sheng-Xiu Liu , Chun-Jun Yang , Pei-Guang Wang , Wen-Ming Zhou , Guo-Shu Lin , Wei-Dong Wu , Xing Fan , Min Gao , Bao-Qi Yang , Wen-Sheng Lu , Zheng Zhang , Kun-Ju Zhu , Song-Ke Shen , Min Li , Xiao-Yan Zhang , Ting-Ting Cao , Wei Ren , Xin Zhang , Jun He , Xian-Fa Tang , Shun Lu , Jian-Qiang Yang , Lin Zhang , Dan-Ni Wang , Feng Yuan , Xian-Yong Yin , Hong-Jie Huang , Hai-Feng Wang , Xin-Yi Lin , Jian-Jun Liu |
2009-02-01 | - |
| 16710414 |
The DNA sequence and biological annotation of human chromosome 1. Nature S G Gregory , K F Barlow , K E McLay , R Kaul , D Swarbreck , A Dunham , C E Scott , K L Howe , K Woodfine , C C A Spencer , M C Jones , C Gillson , S Searle , Y Zhou , F Kokocinski , L McDonald , R Evans , K Phillips , A Atkinson , R Cooper , C Jones , R E Hall , T D Andrews , C Lloyd , R Ainscough , J P Almeida , K D Ambrose , F Anderson , R W Andrew , R I S Ashwell , K Aubin , A K Babbage , C L Bagguley , J Bailey , H Beasley , G Bethel , C P Bird , S Bray-Allen , J Y Brown , A J Brown , D Buckley , J Burton , J Bye , C Carder , J C Chapman , S Y Clark , G Clarke , C Clee , V Cobley , R E Collier , N Corby , G J Coville , J Davies , R Deadman , M Dunn , M Earthrowl , A G Ellington , H Errington , A Frankish , J Frankland , L French , P Garner , J Garnett , L Gay , M R J Ghori , R Gibson , L M Gilby , W Gillett , R J Glithero , D V Grafham , C Griffiths , S Griffiths-Jones , R Grocock , S Hammond , E S I Harrison , E Hart , E Haugen , P D Heath , S Holmes , K Holt , P J Howden , A R Hunt , S E Hunt , G Hunter , J Isherwood , R James , C Johnson , D Johnson , A Joy , M Kay , J K Kershaw , M Kibukawa , A M Kimberley , A King , A J Knights , H Lad , G Laird , S Lawlor , D A Leongamornlert , D M Lloyd , J Loveland , J Lovell , M J Lush , R Lyne , S Martin , M Mashreghi-Mohammadi , L Matthews , N S W Matthews , S McLaren , S Milne , S Mistry , M J F Moore , T Nickerson , C N O'Dell , K Oliver , A Palmeiri , S A Palmer , A Parker , D Patel , A V Pearce , A I Peck , S Pelan , K Phelps , B J Phillimore , R Plumb , J Rajan , C Raymond , G Rouse , C Saenphimmachak , H K Sehra , E Sheridan , R Shownkeen , S Sims , C D Skuce , M Smith , C Steward , S Subramanian , N Sycamore , A Tracey , A Tromans , Z Van Helmond , M Wall , J M Wallis , S White , S L Whitehead , J E Wilkinson , D L Willey , H Williams , L Wilming , P W Wray , Z Wu , A Coulson , M Vaudin , J E Sulston , R Durbin , T Hubbard , R Wooster , I Dunham , N P Carter , G McVean , M T Ross , J Harrow , M V Olson , S Beck , J Rogers , D R Bentley , R Banerjee , S P Bryant , D C Burford , W D H Burrill , S M Clegg , P Dhami , O Dovey , L M Faulkner , S M Gribble , C F Langford , R D Pandian , K M Porter , E Prigmore |
2006-05-18 | - |
| 15854049 |
J. Invest. Dermatol. Benjamin Jackson , Claudia M L J Tilli , Matthew J Hardman , Ariel A Avilion , Michael C MacLeod , Gillian S Ashcroft , Carolyn Byrne |
2005-05-01 |
LCE4A,
LCE5A,
LCE2B,
LCE1A,
LCE1B,
LCE1C,
LCE1D,
LCE1E,
LCE1F,
LCE2A,
LCE2C,
LCE2D,
LCE3A,
LCE3B,
LCE3C,
LCE3E,
LCE6A,
LCEP1,
LCEP2,
LCEP4,
LCEP3,
LCE3D
|
| 15489334 |
Genome Res. Daniela S Gerhard , Lukas Wagner , Elise A Feingold , Carolyn M Shenmen , Lynette H Grouse , Greg Schuler , Steven L Klein , Susan Old , Rebekah Rasooly , Peter Good , Mark Guyer , Allison M Peck , Jeffery G Derge , David Lipman , Francis S Collins , Wonhee Jang , Steven Sherry , Mike Feolo , Leonie Misquitta , Eduardo Lee , Kirill Rotmistrovsky , Susan F Greenhut , Carl F Schaefer , Kenneth Buetow , Tom I Bonner , David Haussler , Jim Kent , Mark Kiekhaus , Terry Furey , Michael Brent , Christa Prange , Kirsten Schreiber , Nicole Shapiro , Narayan K Bhat , Ralph F Hopkins , Florence Hsie , Tom Driscoll , M Bento Soares , Tom L Casavant , Todd E Scheetz , Michael J Brown-stein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Yulan Piao , Dawood B Dudekula , Minoru S H Ko , Koichi Kawakami , Yutaka Suzuki , Sumio Sugano , C E Gruber , M R Smith , Blake Simmons , Troy Moore , Richard Waterman , Stephen L Johnson , Yijun Ruan , Chia Lin Wei , S Mathavan , Preethi H Gunaratne , Jiaqian Wu , Angela M Garcia , Stephen W Hulyk , Edwin Fuh , Ye Yuan , Anna Sneed , Carla Kowis , Anne Hodgson , Donna M Muzny , John McPherson , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madari , Alice C Young , Keith D Wetherby , Steven J Granite , Peggy N Kwong , Charles P Brinkley , Russell L Pearson , Gerard G Bouffard , Robert W Blakesly , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Malachi Griffith , Obi L Griffith , Martin I Krzywinski , Nancy Liao , Ryan Morin , Ryan Morrin , Diana Palmquist , Anca S Petrescu , Ursula Skalska , Duane E Smailus , Jeff M Stott , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Robert A Holt , Agnes Baross , Marco A Marra , Sandra Clifton , Kathryn A Makowski , Stephanie Bosak , Joel Malek , MGC Project Team |
2004-10-01 |
Ldlrap1,
Dnajc3,
Rnaset2a,
Btnl1,
Isg15,
Cyp3a41b,
Ly6c2,
Ccl21b,
Eif3j2,
Mup18,
Lrrc19,
Rcc1,
1700047I17Rik2,
Pcsk9,
Adat3,
Tdrd7,
Sco2,
Gpr153,
Pafah2,
Gm44504,
H6pd,
Adprhl2,
Gpn2,
Rusc2,
Stx12,
Ppp1r8,
Smpdl3b,
Fam46b,
Bsdc1,
Slc44a1,
Zfand2a,
Rubcn,
Kifc1,
Pifo,
C030017K20Rik,
Cbarp,
Rpl5,
Micalcl,
Atg14,
Lrrc8c,
Noc4l,
Nsun5,
Psph,
Trrap,
Mapre3,
Ube3c,
Tbc1d14,
Hscb,
Tyw1,
Emilin1,
Rab28,
Pot1a,
Parp11,
Tada3,
Tra2a,
Brk1,
Fbxl14,
Phrf1,
Plekha1,
Gm21975,
Ric8a,
Mob2,
Prkd2,
Ccp110,
Vrk3,
Grwd1,
Nlrp6,
Trim68,
Psip1,
Spred3,
Faap24,
Ints4,
Rrp8,
Unc45a,
Igflr1,
Sf3b3,
D8Ertd738e,
Usb1,
Champ1,
Smim19,
Exoc8,
Gadd45gip1,
Phkb,
Dohh,
Fam192a,
Enkd1,
Taf5l,
Zdhhc7,
Snapc2,
Ak6,
Gpat4,
Dcun1d2,
Ankrd10,
Cog4,
Hinfp,
Lars2,
Xylb,
Imp3,
Cmtm7
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
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目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
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目前还没有研究热点人员