| Type | Description |
|---|---|
| Definition | RAB11 family interacting protein 4 |
| Date | Results | Publications |
|---|---|---|
| 2019-03-21 15:57:00 | Rab11 FIP4 was also discovered through a yeast two-hybrid screen for Arf5 effectors and named Arfophilin-2, as described here. Rab11 FIP4/Arfophilin-2 was shown to localize to a perinuclear compartment, the centrosome, and focal adhesions in HeLa cells. Rab11 FIP4/Arfophilin-2 over-expression was shown to cluster the Rab11-positive endosomal recycling compartment around the centrosome. | 12857874 |
| 2018-08-18 12:09:00 | Rab11-FIP4 expression promotes migration and invasion of colon cancer cells and correlates with poor prognosis. | 29257314 |
| 2017-04-29 12:49:00 | Our findings suggest that overexpression of Rab11-FIP4 predicts poor clinical outcomes for pancreatic cancer and contributes to pancreatic tumor progression. | 28035375 |
| 2016-04-02 10:42:00 | Results show the expression of Rab11-FIP4 upregulated in hepatocellular carcinoma (HCC) and correlated with poor prognosis. Rab11-FIP4 dramatically contributed to HCC metastasis via phosphorylation of PRAS40. | 25745995 |
| 2010-06-30 22:04:00 | Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | 20379614 |
| Type | IDs |
|---|---|
| Synonymous | FIP4-Rab11, RAB11-FIP4 |
| Gene |
UniProtKB-ID:
RFIP4_HUMAN
UniprotKB:
Q86YS3
UniParc:
UPI000000D857,
UPI000050AAEF
EMBL:
AK097424,
BC101517,
BC093914,
AJ314646,
AB058724,
AL831830,
AY169244
Ensembl:
ENSG00000131242
KO:
hsa:84440
|
| Nucleutide sequences |
EMBL-CDS:
BAC05045.1,
BAB47450.1,
CAD38543.1,
AAI01518.1,
AAO21970.1,
CAC44535.1,
AAH93914.1
Ensembl_TRS:
ENST00000621161,
ENST00000394744
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000378227,
ENSP00000482620
RefSeq:
NP_001290471.2,
NP_001333678.1,
NP_116321.2,
NP_001333676.1,
NP_001333677.1
|
| Others |
UniRef100:
UniRef100_Q86YS3
UniRef90:
UniRef90_Q86YS3
UniRef50:
UniRef50_Q86YS3
UniGene:
Hs.406788
CCDS:
CCDS11267.1,
CCDS76985.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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