| Type | Description |
|---|---|
| Definition | dual specificity tyrosine phosphorylation regulated kinase 3 |
| Date | Results | Publications |
|---|---|---|
| 2019-05-18 11:51:00 | Study shows that the auto-phosphorylation of S350 of DYRK3 stabilizes the protein and positively regulates the functional activity. The S350 residue is located between N-lobe and C-lobe and its auto-phosphorylation mediates hydrogen bond interactions with many nearby residues from C-lobe domain and alphaC-helix to stabilize overall structure. | 29634919 |
| 2019-01-19 10:03:00 | a mechanism in which the dilution of phase-separating proteins during nuclear-envelope breakdown and the DYRK3-dependent degree of their solubility combine to allow cells to dissolve and condense several membraneless organelles during mitosis | 29973724 |
| 2013-04-20 14:03:00 | Study identified the dual specificity tyrosine-phosphorylation-regulated kinase 3 (DYRK3) as a protein with the ability to condense P-granule-like speckles in the cytosol and to prevent stress granule dissolution via its N-terminal domain when it is in a kinase-inactive form. | 23415227 |
| 2011-12-10 11:19:00 | the lipid raft-dependent endocytosis process mediates C. neoformans internalization into HBMEC and the CD44 protein of the hosts, cytoskeleton, and intracellular kinase-DYRK3 are involved in this process | 21693704 |
| 2010-05-31 11:55:00 | DYRK1A and DYRK3 promote cell survival through phosphorylation and activation of SIRT1. | 20167603 |
| Type | IDs |
|---|---|
| Synonymous | DYRK5, RED, REDK, hYAK3-2 |
| Gene |
UniProtKB-ID:
DYRK3_HUMAN
UniprotKB:
O43781
UniParc:
UPI0000071267,
UPI000006E56E
EMBL:
AF186774,
AF186773,
BC015501,
AF327561,
AL591846,
Y12735,
AY590695,
CH471100
Ensembl:
ENSG00000143479
KO:
hsa:8444
|
| Nucleutide sequences |
EMBL-CDS:
CAA73266.2,
AAG17029.1,
AAG17028.1,
EAW93534.1,
AAH15501.1,
AAT06103.1,
EAW93533.1,
AAK16443.1
Ensembl_TRS:
ENST00000367106,
ENST00000367109,
ENST00000367108
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000356073,
ENSP00000356075,
ENSP00000356076
RefSeq:
XP_011508363.1,
NP_003573.2,
XP_005273372.1,
NP_001004023.1
|
| Others |
UniRef100:
UniRef100_O43781
UniRef90:
UniRef90_O43781
UniRef50:
UniRef50_O43781
UniGene:
Hs.164267
CCDS:
CCDS30999.1,
CCDS31000.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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