| Type | Description |
|---|---|
| Definition | SET domain containing 3, actin histidine methyltransferase |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:13:00 | The methyltransferase SETD3-mediated histidine methylation: Biological functions and potential implications in cancers. | 33157163 |
| 2021-02-20 13:33:00 | Characterization of SETD3 methyltransferase-mediated protein methionine methylation. | 32503840 |
| 2020-11-21 13:26:00 | SETD3 acts as a prognostic marker in breast cancer patients and modulates the viability and invasion of breast cancer cells. | 32042016 |
| 2020-10-24 14:03:00 | An engineered variant of SETD3 methyltransferase alters target specificity from histidine to lysine methylation. | 31911441 |
| 2020-07-11 10:37:00 | Findings indicate that SET domain protein 3 (SETD3) down-regulated the expression of kinesin light chain 4 (KLC4), contributing to the radiosensitivity of cervical cancer cells, suggesting targeting SETD3 might be a potential strategy for the clinical management of cervical cancer. | 31235251 |
| Type | IDs |
|---|---|
| Synonymous | C14orf154, hSETD3 |
| Gene |
UniProtKB-ID:
SETD3_HUMAN,
A0A024R6K3_HUMAN
UniprotKB:
Q86TU7,
A0A024R6K3
UniParc:
UPI000000CC6D,
UPI000000CC6C,
UPI00001FDB4E
EMBL:
AL359581,
BC120967,
BX161471,
BC148251,
BC142995,
AL110504,
AK026680,
BC009054,
BC127625,
AL132819,
AK302882,
CH471061,
BC120968,
BX161441,
BC127624
Ensembl:
ENSG00000183576
KO:
hsa:84193
|
| Nucleutide sequences |
EMBL-CDS:
AAI20969.1,
EAW81664.1,
AAI42996.1,
AAI27626.1,
AAI27625.1,
BAB15525.1,
BAG64060.1,
AAI48252.1,
CAD61927.1,
EAW81665.1,
AAI20968.1,
CAH56365.1,
CAD61911.1,
AAH09054.2,
EAW81667.1,
EAW81666.1
Gene_ORFName:
hCG_24635
Ensembl_TRS:
ENST00000329331,
ENST00000331768
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000327436,
ENSP00000327910
RefSeq:
XP_016877191.1,
XP_016877188.1,
XP_011535537.1,
XP_011535535.1,
XP_011535536.1,
XP_016877189.1,
XP_011535534.1,
NP_115609.2,
XP_011535533.2,
XP_005268184.1,
XP_016877190.1,
NP_954574.1
|
| Others |
UniRef100:
UniRef100_Q86TU7
UniRef90:
UniRef90_Q86TU7
UniRef50:
UniRef50_Q86TU7
UniGene:
Hs.510407
CCDS:
CCDS9951.1,
CCDS9952.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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