| Type | Description |
|---|---|
| Definition | farnesyl diphosphate synthase |
| Date | Results | Publications |
|---|---|---|
| 2016-01-30 10:45:00 | data indicate that FPPS may play an important role in Ang II-induced fibrotic responses in VSMCs | 25847782 |
| 2014-06-14 13:04:00 | Inhibition of farnesyl pyrophosphate synthase prevents angiotensin II-induced cardiac fibrosis in vitro. | 24527834 |
| 2010-01-21 00:00:00 | This is the first report to show that chronic inhibition of farnesyl pyrophosphate synthase attenuates the development of cardiac hypertrophy and fibrosis. | 19800872 |
| 2010-01-21 00:00:00 | inhibition of FPP synthase by alendronate reduces RhoA activation by diminishing geranylgeranylation which prevents Ang II-induced hypertrophic responses in neonatal cardiomyocytes. | 19716825 |
| Type | IDs |
|---|---|
| Synonymous | Ac2-125, FPS |
| Gene |
UniProtKB-ID:
FPPS_RAT,
F1LND7_RAT
UniprotKB:
P05369,
F1LND7
UniParc:
UPI00001679A9,
UPI000012ABB9
EMBL:
M17300,
AC097039,
CH473976,
M34477,
BC059125
Ensembl:
ENSRNOG00000043377
KO:
rno:83791
|
| Nucleutide sequences |
EMBL-CDS:
AAH59125.1,
AAA41143.1,
AAA40960.1,
EDM00669.1
Gene_ORFName:
rCG_62519
Ensembl_TRS:
ENSRNOT00000065065
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000058918
RefSeq:
NP_114028.1
|
| Others |
UniRef100:
UniRef100_A0A0G2JXT3,
UniRef100_P05369
UniRef90:
UniRef90_P05369
UniRef50:
UniRef50_P14324
UniGene:
Rn.2848
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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