| Type | Description |
|---|---|
| Definition | otoferlin |
| Date | Results | Publications |
|---|---|---|
| 2021-03-06 13:25:00 | Altered Gap Junction Network Topography in Mouse Models for Human Hereditary Deafness. | 33036242 |
| 2020-06-13 11:25:00 | Study shows the viral expression of truncated forms of otoferlin can partially rescue the fast and transient release component of exocytosis in mouse hair cells lacking otoferlin, yet cannot sustain exocytosis after long repeated stimulation. | 30833506 |
| 2018-07-07 10:57:00 | Otoferlin thus functions as a Ca(2+) sensor, setting the rates of primed vesicle fusion with the presynaptic plasma membrane and synaptic vesicle pool replenishment in the inner hair cell active zone. | 29111973 |
| 2016-08-27 11:56:00 | Furthermore, this F-actin mesh network attached to the synaptic ribbons directly influences the efficiency of otoferlin-dependent exocytosis and its sensitivity to intracellular hydrostatic pressure. | 26568308 |
| 2015-10-31 11:32:00 | Mice that carry a mutation in a calcium binding domain of Otoferlin, the putative calcium sensor at hair cell synapses, have normal distortion product otoacoustic emissions (DPOAEs), but auditory brain stem responses (ABRs) are absent. | 25253474 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
OTOF_MOUSE,
E9PYR6_MOUSE,
A0A2Z2CEU0_MOUSE,
A0A0R4J1K2_MOUSE
UniprotKB:
Q9ESF1,
E9PYR6,
A0A2Z2CEU0,
A0A0R4J1K2
UniParc:
UPI0000027833,
UPI000185D56F,
UPI000002B035,
UPI0003D751A3,
UPI0000F3B7F9,
UPI0000D8AA9B
EMBL:
AF183184,
AY586513,
AC242405,
AC157761,
BC150702,
AK033317,
KX060996,
AF183183,
AC175379
Ensembl:
ENSMUSG00000062372
KO:
mmu:83762
|
| Nucleutide sequences |
EMBL-CDS:
AAG12989.1,
BAC28229.1,
AAI50703.1,
AAG12990.1,
AAT40586.1,
AOX24136.1
Ensembl_TRS:
ENSMUST00000074171,
ENSMUST00000114747
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000073803,
ENSMUSP00000110395
RefSeq:
XP_011239104.1,
NP_001273350.1,
XP_017176674.1,
NP_114081.2,
XP_006504272.1,
NP_001093865.1,
XP_006504269.1,
NP_001300696.1,
XP_017176675.1,
XP_006504271.1
|
| Others |
UniRef100:
UniRef100_A0A2Z2CEU0,
UniRef100_Q9ESF1,
UniRef100_E9PYR6,
UniRef100_A0A0R4J1K2
UniRef90:
UniRef90_Q9HC10
UniRef50:
UniRef50_Q9HC10
UniGene:
Mm.244502
CCDS:
CCDS51452.1,
CCDS19157.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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