| Type | Description |
|---|---|
| Definition | two-pore channel 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-07-13 11:14:00 | Study results in mesophyll vacuoles from Arabidopsis show that the vacuolar K+-conducting TPC1 and TPK1/TPK3 channels act in concert to provide for Ca2+- and voltage-induced electrical excitability to the central organelle of plant cells. | 31201323 |
| 2018-10-20 10:38:00 | Structural basis for activation of voltage sensor domains in an ion channel TPC1. | 30190435 |
| 2018-08-04 11:31:00 | variant (TPC1D454N) depolarizes endomembranes by increasing cation fluxes towards the cytosol | 28885692 |
| 2018-05-12 11:16:00 | The ion selectivity of AtTPC1 was determined and compared with the selectivity of human TPC2. TPC1 is selective for Ca(2+) over Na(+), but nonselective among monovalent Li(+), Na(+), and K(+)). AtTPC1 could be converted to a Na(+)-selective channel by mimicking the selectivity filter of HsTPC2. Key residues were identified in the TPC filters that differentiate this selectivity. A Na+-selective mutant was characterized. | 28096396 |
| 2017-09-23 13:31:00 | TPC1 role in the systemic response to salt stress | 27261066 |
| Type | IDs |
|---|---|
| Synonymous | ATCCH1, ATTPC1, CALCIUM CHANNEL 1, FATTY ACID OXYGENATION UPREGULATED 2, FOU2, T5L23.5, two-pore channel 1, two-pore channel 1 |
| Gene |
UniProtKB-ID:
TPC1_ARATH,
B9DFD5_ARATH
UniprotKB:
Q94KI8,
B9DFD5
UniParc:
UPI00000AB4D0
EMBL:
CP002687,
AC005142,
AF360372,
AF071527,
AL161497,
AK316725,
AB053952
EnsemblGenome:
AT4G03560
KO:
ath:AT4G03560
|
| Nucleutide sequences |
EMBL-CDS:
AEE82337.1,
AAD15312.1,
AAK39554.1,
CAB77841.1,
BAB55460.1,
AAD11598.1,
BAH19452.1
Gene_ORFName:
T5L23.5,
F9H3.19
EnsemblGenome_TRS:
AT4G03560.1
|
| Protein sequencees |
EnsemblGenome_PRO:
AT4G03560.1
RefSeq:
NP_567258.1
|
| Others |
UniRef100:
UniRef100_Q94KI8
UniRef90:
UniRef90_Q94KI8
UniRef50:
UniRef50_Q94KI8
UniGene:
At.3957
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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