| Type | Description |
|---|---|
| Definition | Cdk5 and Abl enzyme substrate 2 |
| Date | Results | Publications |
|---|---|---|
| 2010-04-07 21:40:00 | Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator) | 20056645 |
| 2010-01-21 00:00:00 | We thus identified ik3-2 as a proapoptotic factor involved in both p53-mediated and p53-independent apoptotic pathways. | 14637168 |
| Type | IDs |
|---|---|
| Synonymous | C20orf150, dJ908M14.2, ik3-2 |
| Gene |
UniProtKB-ID:
CABL2_HUMAN
UniprotKB:
Q9BTV7
UniParc:
UPI00001AEA34
EMBL:
AL121832,
BC003122
Ensembl:
ENSG00000149679
KO:
hsa:81928
|
| Nucleutide sequences |
EMBL-CDS:
AAH03122.1
Ensembl_TRS:
ENST00000279101
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000279101
RefSeq:
NP_112492.2
|
| Others |
UniRef100:
UniRef100_Q9BTV7
UniRef90:
UniRef90_Q9BTV7
UniRef50:
UniRef50_Q9BTV7
UniGene:
Hs.301040
CCDS:
CCDS33503.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 28611215 |
Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing. Proc. Natl. Acad. Sci. U.S.A. Teng Fei , Yiwen Chen , Tengfei Xiao , Wei Li , Laura Cato , Peng Zhang , Maura B Cotter , Michaela Bowden , Rosina T Lis , Shuang G Zhao , Qiu Wu , Felix Y Feng , Massimo Loda , Housheng Hansen He , X Shirley Liu , Myles Brown |
2017-06-27 | - |
| 28514442 |
Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper |
2017-05-25 | - |
| 27433848 |
BRCA2 mediates centrosome cohesion via an interaction with cytoplasmic dynein. Cell Cycle Sadiya Malik , Hiroko Saito , Miho Takaoka , Yoshio Miki , Akira Nakanishi |
2016-08-17 | - |
| 26186194 |
The BioPlex Network: A Systematic Exploration of the Human Interactome. Cell Edward L Huttlin , Lily Ting , Raphael J Bruckner , Fana Gebreab , Melanie P Gygi , John Szpyt , Stanley Tam , Gabriela Zarraga , Greg Colby , Kurt Baltier , Rui Dong , Virginia Guarani , Laura Pontano Vaites , Alban Ordureau , Ramin Rad , Brian K Erickson , Martin Wühr , Joel Chick , Bo Zhai , Deepak Kolippakkam , Julian Mintseris , Robert A Obar , Tim Harris , Spyros Artavanis-Tsakonas , Mathew E Sowa , Pietro De Camilli , Joao A Paulo , J Wade Harper , Steven P Gygi |
2015-07-16 | - |
| 25852190 |
Sci Signal Jonathan So , Adrian Pasculescu , Anna Y Dai , Kelly Williton , Andrew James , Vivian Nguyen , Pau Creixell , Erwin M Schoof , John Sinclair , Miriam Barrios-Rodiles , Jun Gu , Aldis Krizus , Ryan Williams , Marina Olhovsky , James W Dennis , Jeffrey L Wrana , Rune Linding , Claus Jorgensen , Tony Pawson , Karen Colwill |
2015-04-07 | - |
| 24737748 |
Identification of susceptibility loci for colorectal cancer in a genome-wide meta-analysis. Hum. Mol. Genet. Nicola Whiffin , Fay J Hosking , Susan M Farrington , Claire Palles , Sara E Dobbins , Lina Zgaga , Amy Lloyd , Ben Kinnersley , Maggie Gorman , Albert Tenesa , Peter Broderick , Yufei Wang , Ella Barclay , Caroline Hayward , Lynn Martin , Daniel D Buchanan , Aung Ko Win , John Hopper , Mark Jenkins , Noralane M Lindor , Polly A Newcomb , Steve Gallinger , David Conti , Fred Schumacher , Graham Casey , Tao Liu , Swedish Low-Risk Colorectal Cancer Study Group , Harry Campbell , Annika Lindblom , Richard S Houlston , Ian P Tomlinson , Malcolm G Dunlop |
2014-09-01 | - |
| 23602568 |
The protein interaction landscape of the human CMGC kinase group. Cell Rep Markku Varjosalo , Salla Keskitalo , Audrey Van Drogen , Helka Nurkkala , Anton Vichalkovski , Ruedi Aebersold , Matthias Gstaiger |
2013-04-25 |
MED6,
PDCD6IP,
FRAT1,
TROAP,
MED16,
RWDD2B,
HUWE1,
EDIL3,
ARPC1B,
HIPK3,
FRY,
AKAP9,
SUGP2,
RASA4,
CDK2,
RBM7,
CDK3,
CDK4,
PSME3,
CDK5,
FLOT1,
DDX39A,
CDK6,
CDK7,
HNRNPR,
DCAF7,
CDK8,
SRRM1,
CDK9,
SF3B4,
CDKN1A,
AKAP8,
CDKN1B,
STUB1,
CDKN1C,
CDKN2A,
PAK4,
CDKN2B,
ZNF267,
CDKN2C,
CDKN2D,
NPM2,
CACNG2,
RBM14,
HAX1,
BAIAP2,
PFDN6,
EIF3M,
SEC23B,
ENOX2,
MYBBP1A,
CHERP,
NOP56,
UBD,
MAB21L2,
DRAP1,
PRPF8,
CDC42EP3,
USP39,
PTGES3,
YME1L1,
NUP50,
HBS1L,
AHCYL1,
ZMYND11,
ZNF460,
CPSF4,
TRAFD1,
MAGED2,
RNPS1,
SUB1,
SRSF8,
AFG3L2,
MSL3,
STIP1,
EBNA1BP2,
SNRNP27,
STON1,
NUDT21,
CPSF6,
CHD2,
SNRNP35,
DIDO1,
WDR5,
KRR1,
FOXN3,
CLASRP,
KPTN,
WDR6,
SUPT16H,
CHEK2,
AKAP11,
EGLN2,
MED8,
GLCCI1,
GABARAP,
U2AF2,
CHUK,
EVI5L
|
| 23455922 |
Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS. Nat. Methods Markku Varjosalo , Roberto Sacco , Alexey Stukalov , Audrey van Drogen , Melanie Planyavsky , Simon Hauri , Ruedi Aebersold , Keiryn L Bennett , Jacques Colinge , Matthias Gstaiger , Giulio Superti-Furga |
2013-04-01 |
FRAT1,
TRAP1,
YAF2,
AKAP9,
G3BP1,
TRIM28,
CDK2,
CDK3,
CDK4,
CDK5,
PATJ,
CDK6,
CDK7,
DCAF7,
SRRM1,
CDK9,
CDKN1A,
CDKN1B,
STUB1,
LOC400927-CSNK1E,
CDKN1C,
SAP18,
BCAS2,
CDKN2A,
CDKN2B,
CDKN2C,
PCGF3,
TUBB4B,
PRMT5,
CDIPT,
SEC23B,
STK25,
PRDX4,
CCT7,
CCT4,
CCT2,
HEXIM1,
IGF2BP3,
IGF2BP2,
CCT8,
YME1L1,
AHCYL1,
SDCCAG3,
TRAFD1,
RNPS1,
PRDX3,
EBNA1BP2,
GCN1,
ILVBL,
TLK2,
WDR5,
CDC37,
WDR6,
RASSF1,
AKAP11,
RPL35,
PDCD10,
TP53RK,
ZNF618,
KLHDC3,
CKS1B,
CKS2,
DCD,
ZC3H18,
HEXIM2,
CREBBP,
FAM199X,
CRY1,
DYNLL2,
PARP1,
MAPK14,
CSK,
CSNK1A1,
CSNK1D,
CSNK1E,
CSNK2A1,
CSNK2A2,
CSNK2B,
C18orf25,
GRK2,
GRK3,
VPS13B,
DVL2,
DYRK1A,
EEF2,
ELAVL1,
EP300,
EWSR1,
ATAD3C,
FASN,
FAM83B,
GPC4,
MAPK15,
FGFR4,
FKBP5,
DHX30,
MAPRE1,
CCT5,
WDFY3
|
| 23535732 |
Nat Genet Rosalind A Eeles , Ali Amin Al Olama , Sara Benlloch , Edward J Saunders , Daniel A Leongamornlert , Malgorzata Tymrakiewicz , Maya Ghoussaini , Craig Luccarini , Joe Dennis , Sarah Jugurnauth-Little , Tokhir Dadaev , David E Neal , Freddie C Hamdy , Jenny L Donovan , Ken Muir , Graham G Giles , Gianluca Severi , Fredrik Wiklund , Henrik Gronberg , Christopher A Haiman , Fredrick Schumacher , Brian E Henderson , Loic Le Marchand , Sara Lindstrom , Peter Kraft , David J Hunter , Susan Gapstur , Stephen J Chanock , Sonja I Berndt , Demetrius Albanes , Gerald Andriole , Johanna Schleutker , Maren Weischer , Federico Canzian , Elio Riboli , Tim J Key , Ruth C Travis , Daniele Campa , Sue A Ingles , Esther M John , Richard B Hayes , Paul D P Pharoah , Nora Pashayan , Kay-Tee Khaw , Janet L Stanford , Elaine A Ostrander , Lisa B Signorello , Stephen N Thibodeau , Dan Schaid , Christiane Maier , Walther Vogel , Adam S Kibel , Cezary Cybulski , Jan Lubinski , Lisa Cannon-Albright , Hermann Brenner , Jong Y Park , Radka Kaneva , Jyotsna Batra , Amanda B Spurdle , Judith A Clements , Manuel R Teixeira , Ed Dicks , Andrew Lee , Alison M Dunning , Caroline Baynes , Don Conroy , Melanie J Maranian , Shahana Ahmed , Koveela Govindasami , Michelle Guy , Rosemary A Wilkinson , Emma J Sawyer , Angela Morgan , David P Dearnaley , Alan Horwich , Robert A Huddart , Vincent S Khoo , Christopher C Parker , Nicholas J Van As , Christopher J Woodhouse , Alan Thompson , Tim Dudderidge , Chris Ogden , Colin S Cooper , Artitaya Lophatananon , Angela Cox , Melissa C Southey , John L Hopper , Dallas R English , Markus Aly , Jan Adolfsson , Jiangfeng Xu , Siqun L Zheng , Meredith Yeager , Rudolf Kaaks , W Ryan Diver , Mia M Gaudet , Mariana C Stern , Roman Corral , Amit D Joshi , Ahva Shahabi , Tiina Wahlfors , Teuvo L J Tammela , Anssi Auvinen , Jarmo Virtamo , Peter Klarskov , Børge G Nordestgaard , M Andreas Røder , Sune F Nielsen , Stig E Bojesen , Afshan Siddiq , Liesel M Fitzgerald , Suzanne Kolb , Erika M Kwon , Danielle M Karyadi , William J Blot , Wei Zheng , Qiuyin Cai , Shannon K McDonnell , Antje E Rinckleb , Bettina Drake , Graham Colditz , Dominika Wokolorczyk , Robert A Stephenson , Craig Teerlink , Heiko Muller , Dietrich Rothenbacher , Thomas A Sellers , Hui-Yi Lin , Chavdar Slavov , Vanio Mitev , Felicity Lose , Srilakshmi Srinivasan , Sofia Maia , Paula Paulo , Ethan Lange , Kathleen A Cooney , Antonis C Antoniou , Daniel Vincent , François Bacot , Daniel C Tessier , COGSâCancer Research UK GWASâELLIPSE (part of GAME-ON) Initiative , Australian Prostate Cancer Bioresource , UK Genetic Prostate Cancer Study Collaborators/British Association of Urological Surgeons' Section of Oncology , UK ProtecT (Prostate testing for cancer and Treatment) Study Collaborators , PRACTICAL (Prostate Cancer Association Group to Investigate Cancer-Associated Alterations in the Genome) Consortium , Zsofia Kote-Jarai , Douglas F Easton |
2013-04-01 | - |
| 20056645 |
Association of mitotic regulation pathway polymorphisms with pancreatic cancer risk and outcome. Cancer Epidemiol Biomarkers Prev Fergus J Couch , Xianshu Wang , William R Bamlet , Mariza de Andrade , Gloria M Petersen , Robert R McWilliams |
2010-01-01 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
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| 排名 | 研究人员 | 文献 |
|---|---|---|
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