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81727 Mvk

81727

Mvk

mevalonate kinase

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition mevalonate kinase

研究结论

Date Results Publications
2019-03-23 11:07:00 This study demonstrated that significant conformational change on a flexible loop connecting the alpha6 and alpha7 helix is induced by the substrate mevalonate binding. Further, the study found that Asp204 is coordinated to the Mg2+ ion. 30735219
2014-09-22 09:38:00 These data suggest that the association of LRBP with luteinizing hormone receptor mRNA results in the translocation of the messenger ribonucleoprotein complex to the p bodies leading to decapping and degradation. 23376535
2014-02-01 12:17:00 These results suggest that hCG-induced down-regulation of LHR mRNA expression is mediated by activation of pathways to increase miR-122 expression, which then increases LRBP expression through the activation of SREBPs. 24064360
2010-01-21 00:00:00 during ligand-induced downregulation, LRBP translocates to ribosomes and associates with LHR mRNA to form an untranslatable ribonucleoprotein complex and inhibits LHR mRNA translation, paving the way to its degradation. 19716387
2010-01-21 00:00:00 LRBP is a translational inhibitor of LHR mRNA in the ovary 16263716

名称对应

Type IDs
Synonymous Lrbp
Gene
UniProtKB-ID: KIME_RAT
UniprotKB: P17256
UniParc: UPI0000112278
EMBL: M29472
KO: rno:81727
Nucleutide sequences
EMBL-CDS: AAA41588.1
Protein sequencees
RefSeq: NP_112325.1
Others
UniRef100: UniRef100_P17256
UniRef90: UniRef90_P17256
UniRef50: UniRef50_P17256
UniGene: Rn.6995

全选

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研究热度

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