Musk - muscle associated receptor tyrosine kinase-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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81725 Musk

基因描述

Type	Description
Definition	muscle associated receptor tyrosine kinase

研究结论

Date	Results	Publications
2018-05-26 11:43:00	Low endurance exercise plus blood flow restriction improves the MuSK and hypertrophy index of both slow and fast muscles of elderly rats probably through the rise of PGC-1alpha expression	29604268
2012-09-01 11:23:00	MuSK kinase activity is necessary for substrate-dependent acetylcholine receptor cluster formation	22210232
2010-08-02 11:31:00	The crystal structure of the Dok7 PH-PTB domains in complex with a phosphopeptide representing the Dok7-binding site on MuSK, is presented.	20603078
2010-01-21 00:00:00	In summary, the presence of MuSK on retinal astrocytes suggests a novel role of MuSK signalling pathways in the CNS.	16899069
2010-01-21 00:00:00	crystal structure of the cytoplasmic domain of unphosphorylated MuSK at 2.05 A resolution, and insights into receptor autoregulation	12220490

名称对应

Type	IDs
Synonymous	Nsk1
Gene	UniProtKB-ID: MUSK_RAT UniprotKB: Q62838 UniParc: UPI000002F308 EMBL: U34985 KO: rno:81725
Nucleutide sequences	EMBL-CDS: AAA90956.1
Protein sequencees	RefSeq: NP_112323.2
Others	UniRef100: UniRef100_Q62838 UniRef90: UniRef90_Q61006 UniRef50: UniRef50_Q61006 UniGene: Rn.10210

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
29604268	Mild aerobic training with blood flow restriction increases the hypertrophy index and MuSK in both slow and fast muscles of old rats: Role of PGC-1Î±. Life Sci. Mohammad-Ali Bahreinipour , Siyavash Joukar , Fariborz Hovanloo , Hamid Najafipour , Vida Naderi , Alireza Rajiamirhasani , Saeed Esmaeili-Mahani	2018-06-01	-
25537362	Identification of a Dutch founder mutation in MUSK causing fetal akinesia deformation sequence. Eur. J. Hum. Genet. M Brigita Tan-Sindhunata , Inge B Mathijssen , Margriet Smit , Frank Baas , Johanna I de Vries , J Patrick van der Voorn , Irma Kluijt , Marleen A Hagen , Eveline W Blom , Erik Sistermans , Hanne Meijers-Heijboer , Quinten Waisfisz , Marjan M Weiss , Alexander J Groffen	2015-09-01	MUSK
26025053	MuSK autoantibodies in myasthenia gravis detected by cell based assay--A multinational study. J. Neuroimmunol. A I Tsonis , P Zisimopoulou , K Lazaridis , J Tzartos , E Matsigkou , V Zouvelou , R Mantegazza , C Antozzi , F Andreetta , A Evoli , F Deymeer , G Saruhan-Direskeneli , H Durmus , T Brenner , A Vaknin , S Berrih-Aknin , A Behin , T Sharshar , M De Baets , M Losen , P Martinez-Martinez , K A Kleopa , E Zamba-Papanicolaou , T Kyriakides , A Kostera-Pruszczyk , P Szczudlik , B Szyluk , D Lavrnic , I Basta , S Peric , C Tallaksen , A Maniaol , C Casasnovas Pons , J Pitha , M JakubÃkova , F Hanisch , S J Tzartos	2015-07-15	-
23382219	Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins. Proc. Natl. Acad. Sci. U.S.A. Rajesh Ghai , Andrea Bugarcic , Huadong Liu , Suzanne J Norwood , Sune Skeldal , Elizabeth J Coulson , Shawn Shun-Cheng Li , Rohan D Teasdale , Brett M Collins	2013-02-19	Nt5dc3, Grm7, Olr1, Bcr, Nr3c2, Adgrv1, Adcyap1r1, Adrb2, Alk, App, Ddr1, Cr2, Cr1l, Egfr, Erbb2, Erbb3, Erbb4, Fgfr1, Flt1, Flt4, Lrp2, Gpr37, Hras, Igf1r, Il4ra, Insr, Itga3, Itgb1, Itgb2, Itgb3, Itgb5, Itgb6, Itgb7, Itln1, Itpr2, Itpr3, Ldlr, Lepr, Lrp1, Lrp8, Tlr7, Gpr37l1, Mttp, Notch1, Notch2, Notch3, Nppb, Npr1, Musk, Ntrk1, Ntrk2, Ntrk3, Pigr, Pla2r1, Ptpra, Ptprb, Ptprn2, Itgb4, Ret, Selp, Il23r, Tnfrsf1a, Trpc1, Tshr, Vipr1, Vldlr, Impg2, P2rx3, Gpr61, P2rx2, Gpr119, Amfr, Insrr, Gpr20, Gpr101, Trpv3, Ror1, Snx17, Fcrl5, Taok2, Gpr62, Gabrq, Cd200r1, Pex5l, Snx31, Loxl4, Rnmt, Gprc5c, Gpr160, Plxdc1, Tm7sf2, Slitrk5, Snx27, Gpr84, Gpr63, Tas1r2, Mcoln1, Lrp1b, ADCYAP1R1
23032192	The neuromuscular junction: selective remodeling of synaptic regulators at the nerve/muscle interface. Mech. Dev. Veit Witzemann , FrÃ©dÃ©ric Chevessier , Pier Giorgio Pacifici , Pessah Yampolsky	2012-09-29	Chrnb1, Agrn, Chrng, Chrne, Dok7, Rapsn, Chrnd, Chrna1, Musk, Lrp4
22210232	The formation of complex acetylcholine receptor clusters requires MuSK kinase activity and structural information from the MuSK extracellular domain. Mol Cell Neurosci Sania Mazhar , Ruth Herbst	2012-04-01	-
22218276	Long-lasting treatment effect of rituximab in MuSK myasthenia. Neurology J DÃaz-Manera , E MartÃnez-HernÃ¡ndez , L Querol , R Klooster , R Rojas-GarcÃa , X SuÃ¡rez-Calvet , J L MuÃ±oz-Blanco , C Mazia , K R Straasheijm , E Gallardo , C JuÃ¡rez , J J Verschuuren , I Illa	2012-01-17	-
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
21419809	Rin-like, a novel regulator of endocytosis, acts as guanine nucleotide exchange factor for Rab5a and Rab22. Biochim Biophys Acta Barbara Woller , Susan Luiskandl , Milica Popovic , Barbara E M Prieler , Gloria Ikonge , Michaela Mutzl , Holger Rehmann , Ruth Herbst	2011-06-01	-
20603078	The cytoplasmic adaptor protein Dok7 activates the receptor tyrosine kinase MuSK via dimerization. Mol Cell Elisa Bergamin , Peter T Hallock , Steven J Burden , Stevan R Hubbard	2010-07-09	-

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