Itpr2 - inositol 1,4,5-trisphosphate receptor, type 2-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

收藏

81678 Itpr2

基因描述

Type	Description
Definition	inositol 1,4,5-trisphosphate receptor, type 2

研究结论

Date	Results	Publications
2017-06-03 12:25:00	The findings provide evidence that IP3R2 expression is transcriptionally regulated by cyclic AMP via CREB binding to CRE elements in its promoter.	28327356
2014-04-26 11:40:00	ITPR2 and hypertrophy specific gene expression is regulated, in part, by a positive feedback regulation between InsP3R2 and calcineurin-NFATc signaling pathways.	24415751
2013-06-08 11:45:00	Inositol 1,4,5-trisphosphate and IP3 receptors act as inhibitors of autophagic processes in cardiomyocytes.	23137780
2012-01-14 10:46:00	Pericanalicular calcium signaling mediated InsP3R2 plays an important role in maintaining bile salt secretion through posttranslational regulation of the bile salt export pump.	21748767
2010-05-31 11:07:00	IP(3)R2 selectively associates with AC6, G alpha(s) also associates with the AC x IP(3)R signaling junction.	20189985

名称对应

Type	IDs
Gene	UniProtKB-ID: ITPR2_RAT UniprotKB: P29995 UniParc: UPI000012D7CA EMBL: X61677, AF329470 KO: rno:81678
Nucleutide sequences	EMBL-CDS: AAK11622.1, CAA43852.1
Protein sequencees	RefSeq: NP_112308.2
Others	UniRef100: UniRef100_P29995 UniRef90: UniRef90_Q9Z329 UniRef50: UniRef50_Q9Z329 UniGene: Rn.89152

全选

{{proteinIndex+1}}

mRNA

Protein

UniprotKB

Description

Refseq

{{protein.nucleotideVersion}}

Ensembl: {{protein.nucleotideEnsembl}}

{{protein.proteinVersion}}

Ensembl: {{protein.proteinEnsembl}}

{{uniprot}}

Definition: {{{protein.definition}}}

Transcript Veriant:{{protein.transcriptVeriant}}

Status: {{protein.status}}

Location

( {{protein.positionStart}}..{{protein.positionEnd}} )

暂无数据

收藏到我的文献

全选

Pubmed编号	文献信息	发表日期	相关基因
28327356	Type 2 inositol trisphosphate receptor gene expression in hepatocytes is regulated by cyclic AMP. Biochem. Biophys. Res. Commun. Emma Kruglov , Meenakshisundaram Ananthanarayanan , Pedro Sousa , Jittima Weerachayaphorn , Mateus T Guerra , Michael H Nathanson	2017-05-06	-
24415751	Calcineurin-NFATc regulates type 2 inositol 1,4,5-trisphosphate receptor (InsP3R2) expression during cardiac remodeling. J Biol Chem Natesan Sankar , Pieter P deTombe , Gregory A Mignery	2014-02-28	-
23884412	The Bcl-2 protein family member Bok binds to the coupling domain of inositol 1,4,5-trisphosphate receptors and protects them from proteolytic cleavage. J Biol Chem Jacqualyn J Schulman , Forrest A Wright , Thomas Kaufmann , Richard J H Wojcikiewicz	2013-08-30	-
23382219	Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins. Proc. Natl. Acad. Sci. U.S.A. Rajesh Ghai , Andrea Bugarcic , Huadong Liu , Suzanne J Norwood , Sune Skeldal , Elizabeth J Coulson , Shawn Shun-Cheng Li , Rohan D Teasdale , Brett M Collins	2013-02-19	Nt5dc3, Grm7, Olr1, Bcr, Nr3c2, Adgrv1, Adcyap1r1, Adrb2, Alk, App, Ddr1, Cr2, Cr1l, Egfr, Erbb2, Erbb3, Erbb4, Fgfr1, Flt1, Flt4, Lrp2, Gpr37, Hras, Igf1r, Il4ra, Insr, Itga3, Itgb1, Itgb2, Itgb3, Itgb5, Itgb6, Itgb7, Itln1, Itpr2, Itpr3, Ldlr, Lepr, Lrp1, Lrp8, Tlr7, Gpr37l1, Mttp, Notch1, Notch2, Notch3, Nppb, Npr1, Musk, Ntrk1, Ntrk2, Ntrk3, Pigr, Pla2r1, Ptpra, Ptprb, Ptprn2, Itgb4, Ret, Selp, Il23r, Tnfrsf1a, Trpc1, Tshr, Vipr1, Vldlr, Impg2, P2rx3, Gpr61, P2rx2, Gpr119, Amfr, Insrr, Gpr20, Gpr101, Trpv3, Ror1, Snx17, Fcrl5, Taok2, Gpr62, Gabrq, Cd200r1, Pex5l, Snx31, Loxl4, Rnmt, Gprc5c, Gpr160, Plxdc1, Tm7sf2, Slitrk5, Snx27, Gpr84, Gpr63, Tas1r2, Mcoln1, Lrp1b, ADCYAP1R1
23137780	Regulation of autophagy in cardiomyocytes by Ins(1,4,5)P(3) and IP(3)-receptors. J. Mol. Cell. Cardiol. Albert Wong , David R Grubb , Nicola Cooley , Jieting Luo , Elizabeth A Woodcock	2013-01-01	Itpr1, Itpr3, Itpr2
23166348	Mutual antagonism between IP(3)RII and miRNA-133a regulates calcium signals and cardiac hypertrophy. J. Cell Biol. Faye M Drawnel , Dagmar Wachten , Jeffery D Molkentin , Marjorie Maillet , Jan Magnus Aronsen , Fredrik Swift , Ivar Sjaastad , Ning Liu , Daniele Catalucci , Katsuhiko Mikoshiba , Chihiro Hisatsune , Hanneke Okkenhaug , Simon R Andrews , Martin D Bootman , H Llewelyn Roderick	2012-11-26	-
21748767	Type 2 inositol 1,4,5-trisphosphate receptor modulates bile salt export pump activity in rat hepatocytes. Hepatology Emma A Kruglov , Samir Gautam , Mateus T Guerra , Michael H Nathanson	2011-11-01	-
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
21436055	Calmodulin protects against alcohol-induced pancreatic trypsinogen activation elicited via Ca2+ release through IP3 receptors. Proc. Natl. Acad. Sci. U.S.A. Julia V Gerasimenko , GyÃ¶rgy Lur , Pawel Ferdek , Mark W Sherwood , Etsuko Ebisui , Alexei V Tepikin , Katsuhiko Mikoshiba , Ole H Petersen , Oleg V Gerasimenko	2011-04-05	Calm1, Calm3, Itpr2, Itpr3
21071436	Activated inositol 1,4,5-trisphosphate receptors are modified by homogeneous Lys-48- and Lys-63-linked ubiquitin chains, but only Lys-48-linked chains are required for degradation. J Biol Chem Danielle A Sliter , Mike Aguiar , Steven P Gygi , Richard J H Wojcikiewicz	2011-01-14	-

研究热度

热点单位

排名	科研单位	文献
{{affIndex+1}}	{{aff.value}}	{{aff.size}}

目前还没有研究热点单位

热点人员

排名	研究人员	文献
{{authorIndex+1}}	{{author.value}}	{{author.size}}

目前还没有研究热点人员

© 2017 biocloud.net版权所有 ICP证：京10042835号