| Type | Description |
|---|---|
| Definition | cysteine proteinase falcipain 2a |
| Date | Results | Publications |
|---|---|---|
| 2019-11-30 11:59:00 | further showed a disease state mutant SPB3-Gly351Ala performed better anti-protease activity against FP2. This study, for the first time, has shown a serpin family inhibitor from human could efficiently inhibit activity of FP2. | 31247344 |
| 2016-01-16 11:32:00 | Data show a falcipain-2 (FP-2)/hemoglobin complex using molecular dynamics and quantum mechanics approaches. | 24943200 |
| 2013-07-20 12:20:00 | Further study revealed that hydrophobic interactions present both in falcipain-2 and falcipain-3 also play important roles in the activation of these enzymes | 23077573 |
| 2013-06-15 11:35:00 | Falcipain 2 Coexists with HDP and Forms a Hz Formation Complex in the Plasmodium Food Vacuole. | 23471987 |
| 2010-01-21 00:00:00 | The data suggest key roles for falcipain-2 and falcipain-3 in the development of erythrocytic malaria parasites and a complex interplay between P. falciparum cysteine and aspartic proteases. | 16890302 |
| Type | IDs |
|---|---|
| Synonymous | PF11_0165 |
| Gene |
UniProtKB-ID:
Q8I6U4_PLAF7
UniprotKB:
Q8I6U4
UniParc:
UPI0000085D81
EMBL:
LN999945
EnsemblGenome:
PF3D7_1115700
KO:
pfa:PF3D7_1115700
|
| Nucleutide sequences |
EMBL-CDS:
CZT98817.1
Gene_ORFName:
PF3D7_1115700
|
| Protein sequencees |
RefSeq:
XP_001347836.1
|
| Others |
UniRef100:
UniRef100_A0A2I0C180
UniRef90:
UniRef90_Q9N6S8
UniRef50:
UniRef50_Q9N6S8
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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