| Type | Description |
|---|---|
| Definition | sterol regulatory element binding transcription factor 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-06-13 11:42:00 | This study was aimed to evaluate the efficacy of isoquercetin on the regulation of lipid metabolism, sterol regulatory element binding transcription factor 1 (SREBP-1C), adenosine monophosphate-activated protein kinase (AMPK), and inflammatory markers in diabetic rats. | 31677037 |
| 2020-06-13 11:15:00 | Lipotoxicity reduced the expression of lipid metabolism-related molecules in ISCs treated with PA, especially SREBP-1c. Overexpression of SREBP-1c in ISCs improved islet viability and insulin secretion in co-cultures. | 30998947 |
| 2020-01-18 11:48:00 | Oral solution of fructose promotes SREBP-1c high-expression in the hypothalamus of Wistar rats. Dietary fructose can change important lipogenic and inflammatory factors in the hypothalamus of rats and it leads to regulation of transcription factors before changes in body mass are evident. | 29366380 |
| 2019-03-23 10:14:00 | BHLHE40 is required for insulin induction of SREBP-1c mRNA in rodent liver. | 29952285 |
| 2019-02-09 10:30:00 | The effect of dietary plant extracts and vegetable oils on hepatic SREBP-1c, Delta5 and Delta6 desaturases has been reported. | 29735017 |
| Type | IDs |
|---|---|
| Synonymous | ADD-1, ADD1, SREBP-1, SREBP-1c, Srebp1 |
| Gene |
UniProtKB-ID:
SRBP1_RAT
UniprotKB:
P56720
UniParc:
UPI00001D03C4,
UPI0000500D2F
EMBL:
AABR03073826,
L16995,
AF286469,
AF286470,
AABR03076830
Ensembl:
ENSRNOG00000003463
KO:
rno:78968
|
| Nucleutide sequences |
EMBL-CDS:
AAG28734.2,
AAG28733.2
Ensembl_TRS:
ENSRNOT00000047053,
ENSRNOT00000004753
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000050057,
ENSRNOP00000004753
RefSeq:
XP_017453030.1,
NP_001263637.1,
NP_001263636.1
|
| Others |
UniRef100:
UniRef100_P56720
UniRef90:
UniRef90_Q9WTN3
UniRef50:
UniRef50_P36956
UniGene:
Rn.198857
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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