| Type | Description |
|---|---|
| Definition | calcium voltage-gated channel auxiliary subunit beta 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-03-02 11:07:00 | Data show that mutant variant V156A results in instability of protein subdomains of beta1a subunit leading to a phenotype of Ca(2+) dysregulation that partly resembles that of other malignant hypertension-linked mutations of DHPR alpha1S subunit. | 29212769 |
| 2016-12-17 10:44:00 | These results provide new insights into the role of muscle-specific proteins on the structural arrangement of alpha1S intracellular loops and point to a new conformational effect of the beta1a subunit in supporting skeletal muscle excitation-contraction coupling. | 27129199 |
| 2011-01-15 10:49:00 | CACNB1, encoding cardiac L-type calcium channel beta 1 subunit, is a potential target for microRNA-328 in transgenic mice. | 21098446 |
| 2010-03-29 11:55:00 | Data show that the length-dependent mechanism of modulating inactivation kinetics of beta(2) calcium channel subunits can be confirmed and extended to the beta(1) calcium channel subunit. | 19821165 |
| Type | IDs |
|---|---|
| Synonymous | CAB1, CACNLB1, CCHLB1 |
| Gene |
UniProtKB-ID:
CACB1_HUMAN
UniprotKB:
Q02641
UniParc:
UPI0000127290,
UPI000002A5CF,
UPI000002A5D0
EMBL:
U86959,
L06110,
U86960,
AK289729,
BC037311,
AB054985,
M76560,
U86952,
U86961,
Z21725,
U86957,
U86953,
L06111,
M92302,
Z21726,
U86955,
U86954,
U86958,
U86956,
L06112,
M92303,
M92301,
CH471152
Ensembl:
ENSG00000067191
KO:
hsa:782
|
| Nucleutide sequences |
EMBL-CDS:
EAW60562.1,
AAA36168.1,
AAA36167.1,
CAA79825.1,
BAB21444.1,
AAA35631.1,
AAA36169.1,
AAA51894.1,
AAH37311.2,
CAA79824.1,
AAB58781.1,
AAA35632.1,
AAA35633.1,
AAB58779.1,
BAF82418.1,
AAB58780.1
Ensembl_TRS:
ENST00000394303,
ENST00000344140,
ENST00000394310
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000345461,
ENSP00000377840,
ENSP00000377847
RefSeq:
NP_954855.1,
XP_016880519.1,
XP_016880515.1,
XP_016880517.1,
XP_006722135.1,
NP_954856.1,
XP_005257703.1,
XP_024306688.1,
XP_016880513.1,
XP_016880514.1,
XP_005257702.1,
XP_016880516.1,
XP_016880518.1,
NP_000714.3
|
| Others |
UniRef100:
UniRef100_Q02641
UniRef90:
UniRef90_Q8R3Z5
UniRef50:
UniRef50_Q8R3Z5
UniGene:
Hs.635
CCDS:
CCDS42311.1,
CCDS45665.1,
CCDS11334.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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