Dok5 - docking protein 5-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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76829 Dok5

基因描述

Type	Description
Definition	docking protein 5

研究结论

Date	Results	Publications
2020-04-18 10:23:00	The study suggests that miR-141-3p inhibits retinal neovascularization in glaucoma mice by impeding the activation of the DOK5-mediated MAPK signaling pathway.	30515784
2014-10-18 13:35:00	IGFBP-5 induces its pro-fibrotic effects, at least in part, via DOK5. IGFBP-5 and DOK5 are both increased in systemic sclerosis fibroblasts and tissues and may thus be acting in concert to promote fibrosis.	24551065
2014-05-10 12:20:00	Dok5 is necessary for NT-3 signaling to block TrkC-induced apoptosis	23954828
2010-03-15 12:05:00	FOXO3a, the PI3K/PKB downstream substrate, acts as a transcriptional repressor to inhibit the expression of Dok-5.	19800350

名称对应

Type	IDs
Synonymous	2700055C10Rik
Gene	UniProtKB-ID: DOK5_MOUSE UniprotKB: Q91ZM9 UniParc: UPI0000022C31 EMBL: AK044148, AF418208, AK012430 Ensembl: ENSMUSG00000027560 KO: mmu:76829
Nucleutide sequences	EMBL-CDS: BAC31799.1, AAL14627.1, BAB28233.1 Ensembl_TRS: ENSMUST00000029075
Protein sequencees	Ensembl_PRO: ENSMUSP00000029075 RefSeq: XP_036018571.1, NP_001157158.1, NP_084037.3
Others	UniRef100: UniRef100_Q91ZM9 UniRef90: UniRef90_Q91ZM9 UniRef50: UniRef50_Q8TEW6 UniGene: Mm.41633 CCDS: CCDS17125.1

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mRNA

Protein

UniprotKB

Description

Refseq

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Location

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Pubmed编号	文献信息	发表日期	相关基因
30515784	MicroRNA-141-3p inhibits retinal neovascularization and retinal ganglion cell apoptosis in glaucoma mice through the inactivation of Docking protein 5-dependent mitogen-activated protein kinase signaling pathway. J. Cell. Physiol. Li-Qiong Zhang , Hao Cui , Yong-Bin Yu , Huan-Qi Shi , Yuan Zhou , Mei-Jiao Liu	2019-06-01	-
30635555	Single-cell transcriptomic analysis of mouse neocortical development. Nat Commun Lipin Loo , Jeremy M Simon , Lei Xing , Eric S McCoy , Jesse K Niehaus , Jiami Guo , E S Anton , Mark J Zylka	2019-01-11	-
24551065	The membrane-associated adaptor protein DOK5 is upregulated in systemic sclerosis and associated with IGFBP-5-induced fibrosis. PLoS One Hidekata Yasuoka , Yukie Yamaguchi , Carol A Feghali-Bostwick	2014-01-01	-
23954828	Dok5 is involved in the signaling pathway of neurotrophin-3 against TrkC-induced apoptosis. Neurosci. Lett. Yanfang Pan , Jing Zhang , Wei Liu , Pengcheng Shu , Bin Yin , Jiangang Yuan , Boqin Qiang , Xiaozhong Peng	2013-10-11	Casp3, Ntf3, Ntrk3, Rbfox3, Dok5, NTF3, DOK5, CASP3
21677750	A conditional knockout resource for the genome-wide study of mouse gene function. Nature William C Skarnes , Barry Rosen , Anthony P West , Manousos Koutsourakis , Wendy Bushell , Vivek Iyer , Alejandro O Mujica , Mark Thomas , Jennifer Harrow , Tony Cox , David Jackson , Jessica Severin , Patrick Biggs , Jun Fu , Michael Nefedov , Pieter J de Jong , A Francis Stewart , Allan Bradley	2011-06-15	-
19800350	Dok-5 is involved in cardiomyocyte differentiation through PKB/FOXO3a pathway. J. Mol. Cell. Cardiol. Jianyan Wen , Qing Xia , Cheng Wang , Wei Liu , Yang Chen , Jing Gao , Yanhua Gong , Bin Yin , Yuannan Ke , Boqin Qiang , Jiangang Yuan , Xiaozhong Peng	2009-12-01	Akt1, Foxo3, Dok5
18287559	GUDMAP: the genitourinary developmental molecular anatomy project. J Am Soc Nephrol Andrew P McMahon , Bruce J Aronow , Duncan R Davidson , Jamie A Davies , Kevin W Gaido , Sean Grimmond , James L Lessard , Melissa H Little , S Steven Potter , Elizabeth L Wilder , Pumin Zhang , GUDMAP project	2008-04-01	-
16919269	A global genomic transcriptional code associated with CNS-expressed genes. Exp. Cell Res. Peter J Bailey , Joanna M Klos , Elisabet Andersson , Mattias KarlÃ©n , Magdalena KÃ¤llstrÃ¶m , Jasmina Ponjavic , Jonas Muhr , Boris Lenhard , Albin Sandelin , Johan Ericson	2006-10-01	-
16602821	BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol Susan Magdaleno , Patricia Jensen , Craig L Brumwell , Anna Seal , Karen Lehman , Andrew Asbury , Tony Cheung , Tommie Cornelius , Diana M Batten , Christopher Eden , Shannon M Norland , Dennis S Rice , Nilesh Dosooye , Sundeep Shakya , Perdeep Mehta , Tom Curran	2006-04-01	-
16141072	The transcriptional landscape of the mammalian genome. Science P Carninci , T Kasukawa , S Katayama , J Gough , M C Frith , N Maeda , R Oyama , T Ravasi , B Lenhard , C Wells , R Kodzius , K Shimokawa , V B Bajic , S E Brenner , S Batalov , A R R Forrest , M Zavolan , M J Davis , L G Wilming , V Aidinis , J E Allen , A Ambesi-Impiombato , R Apweiler , R N Aturaliya , T L Bailey , M Bansal , L Baxter , K W Beisel , T Bersano , H Bono , A M Chalk , K P Chiu , V Choudhary , A Christoffels , D R Clutterbuck , M L Crowe , E Dalla , B P Dalrymple , B de Bono , G Della Gatta , D di Bernardo , T Down , P Engstrom , M Fagiolini , G Faulkner , C F Fletcher , T Fukushima , M Furuno , S Futaki , M Gariboldi , P Georgii-Hemming , T R Gingeras , T Gojobori , R E Green , S Gustincich , M Harbers , Y Hayashi , T K Hensch , N Hirokawa , D Hill , L Huminiecki , M Iacono , K Ikeo , A Iwama , T Ishikawa , M Jakt , A Kanapin , M Katoh , Y Kawasawa , J Kelso , H Kitamura , H Kitano , G Kollias , S P T Krishnan , A Kruger , S K Kummerfeld , I V Kurochkin , L F Lareau , D Lazarevic , L Lipovich , J Liu , S Liuni , S McWilliam , M Madan Babu , M Madera , L Marchionni , H Matsuda , S Matsuzawa , H Miki , F Mignone , S Miyake , K Morris , S Mottagui-Tabar , N Mulder , N Nakano , H Nakauchi , P Ng , R Nilsson , S Nishiguchi , S Nishikawa , F Nori , O Ohara , Y Okazaki , V Orlando , K C Pang , W J Pavan , G Pavesi , G Pesole , N Petrovsky , S Piazza , J Reed , J F Reid , B Z Ring , M Ringwald , B Rost , Y Ruan , S L Salzberg , A Sandelin , C Schneider , C SchÃ¶nbach , K Sekiguchi , C A M Semple , S Seno , L Sessa , Y Sheng , Y Shibata , H Shimada , K Shimada , D Silva , B Sinclair , S Sperling , E Stupka , K Sugiura , R Sultana , Y Takenaka , K Taki , K Tammoja , S L Tan , S Tang , M S Taylor , J Tegner , S A Teichmann , H R Ueda , E van Nimwegen , R Verardo , C L Wei , K Yagi , H Yamanishi , E Zabarovsky , S Zhu , A Zimmer , W Hide , C Bult , S M Grimmond , R D Teasdale , E T Liu , V Brusic , J Quackenbush , C Wahlestedt , J S Mattick , D A Hume , C Kai , D Sasaki , Y Tomaru , S Fukuda , M Kanamori-Katayama , M Suzuki , J Aoki , T Arakawa , J Iida , K Imamura , M Itoh , T Kato , H Kawaji , N Kawagashira , T Kawashima , M Kojima , S Kondo , H Konno , K Nakano , N Ninomiya , T Nishio , M Okada , C Plessy , K Shibata , T Shiraki , S Suzuki , M Tagami , K Waki , A Watahiki , Y Okamura-Oho , H Suzuki , J Kawai , Y Hayashizaki , FANTOM Consortium , RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)	2005-09-02	-

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