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76650 Srxn1

76650

Srxn1

sulfiredoxin 1 homolog (S. cerevisiae)

protein-coding

Mus musculus

基因描述

Type Description
Definition sulfiredoxin 1 homolog (S. cerevisiae)

研究结论

Date Results Publications
2020-06-06 13:58:00 These results demonstrated that Srxn1 protects podocytes from high glucose-induced injury by promoting the activation of Nrf2/ARE signaling associated with inactivating GSK-3beta, indicating a potential role of Srxn1 in diabetic nephropathy. 31284950
2019-12-28 10:54:00 essential for normal responses to GnRH stimulation and plays an important role in reactive oxygen species management 31504396
2016-04-30 10:22:00 sulfiredoxin is degraded by Lon in a manner dependent on PrxIII hyperoxidation state. 26236015
2014-06-28 13:52:00 Srx is one of the critical components that contribute to mouse skin tumorigenesis in vivo. 24503444
2013-08-03 10:32:00 data provide in vivo evidence that loss of Srx renders mice resistant to azoxymethane/dextran sulfate sodium-induced colon carcinogenesis, suggesting that Srx has a critical oncogenic role in cancer development 23393226

名称对应

Type IDs
Synonymous 1700127B04Rik, AI854065, AW488194, Npn3, Srx, Srx1, TX01
Gene
UniProtKB-ID: SRXN1_MOUSE, A2AQU8_MOUSE
UniprotKB: Q9D975, A2AQU8
UniParc: UPI00001EE298, UPI00000041DC
EMBL: AK159613, AK089976, BC049957, BC011325, AK007296, AL845161
Ensembl: ENSMUSG00000032802
KO: mmu:76650
Nucleutide sequences
EMBL-CDS: BAC41025.1, BAE35230.1, BAB24939.1, AAH49957.1, AAH11325.1
Ensembl_TRS: ENSMUST00000041500
Protein sequencees
Ensembl_PRO: ENSMUSP00000046196
RefSeq: NP_083964.2, XP_036018567.1
Others
UniRef100: UniRef100_A2AQU8, UniRef100_Q9D975
UniRef90: UniRef90_Q9D975
UniRef50: UniRef50_Q9BYN0
UniGene: Mm.218639

全选

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