Type | Description |
---|---|
Definition | inositol hexaphosphate kinase 2 |
Date | Results | Publications |
---|---|---|
2019-10-26 10:34:00 | IP6K2 binds selectively to the neuronal protein 4.1N. Both are highly expressed in granule cells of the cerebellum. In IP6K2 knock-out mice, IP6K2-4.1N interactions in granule cells regulate Purkinje cell morphology, the viability of cerebellar neurons, and psychomotor behavior. | 30006360 |
2015-05-09 11:03:00 | IP6K2 is a major mediator of cancer cell migration and tumor metastasis, acting by enhancing cell-matrix adhesion and decreasing cell-cell adhesion. | 25617365 |
2013-12-14 12:02:00 | FGF2-signaling involves the inositol polyphosphate cascade, including inositol hexakisphosphate kinase (IP6K), and demonstrate that IP6K1,2 regulates Runx2 and osteoblast gene expression. | 23322705 |
2010-01-21 00:00:00 | Gene deletion of inositol hexakisphosphate kinase 2 predisposes to aerodigestive tract carcinoma. | 19430495 |
Type | IDs |
---|---|
Synonymous | 1500005N04Rik, AW050208, Ihpk2 |
Gene |
UniProtKB-ID:
IP6K2_MOUSE,
A0A0A6YXT7_MOUSE
UniprotKB:
Q80V72,
A0A0A6YXT7
UniParc:
UPI0000D8B304,
UPI0001549A3C
EMBL:
AC173341,
AC168054,
BC039922
Ensembl:
ENSMUSG00000032599,
ENSMUSG00000106672
KO:
mmu:76500
|
Nucleutide sequences |
EMBL-CDS:
AAH39922.1
Ensembl_TRS:
ENSMUST00000201336,
ENSMUST00000085018,
ENSMUST00000192307
|
Protein sequencees |
Ensembl_PRO:
ENSMUSP00000082091,
ENSMUSP00000144020,
ENSMUSP00000142134
RefSeq:
XP_006511918.1,
NP_001366531.1,
NP_001366532.1,
XP_036011296.1,
NP_001366530.1,
XP_006511917.1,
XP_006511919.1,
NP_083910.2,
XP_006511914.1,
XP_006511916.1,
NP_001366529.1
|
Others |
UniRef100:
UniRef100_A0A0A6YXT7,
UniRef100_Q80V72
UniRef90:
UniRef90_Q80V72,
UniRef90_A0A0A6YXT7
UniRef50:
UniRef50_A4IHU0,
UniRef50_Q80V72
UniGene:
Mm.276336,
Mm.490338
CCDS:
CCDS23537.1
|