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76500 Ip6k2

76500

Ip6k2

inositol hexaphosphate kinase 2

protein-coding

Mus musculus

基因描述

Type Description
Definition inositol hexaphosphate kinase 2

研究结论

Date Results Publications
2019-10-26 10:34:00 IP6K2 binds selectively to the neuronal protein 4.1N. Both are highly expressed in granule cells of the cerebellum. In IP6K2 knock-out mice, IP6K2-4.1N interactions in granule cells regulate Purkinje cell morphology, the viability of cerebellar neurons, and psychomotor behavior. 30006360
2015-05-09 11:03:00 IP6K2 is a major mediator of cancer cell migration and tumor metastasis, acting by enhancing cell-matrix adhesion and decreasing cell-cell adhesion. 25617365
2013-12-14 12:02:00 FGF2-signaling involves the inositol polyphosphate cascade, including inositol hexakisphosphate kinase (IP6K), and demonstrate that IP6K1,2 regulates Runx2 and osteoblast gene expression. 23322705
2010-01-21 00:00:00 Gene deletion of inositol hexakisphosphate kinase 2 predisposes to aerodigestive tract carcinoma. 19430495

名称对应

Type IDs
Synonymous 1500005N04Rik, AW050208, Ihpk2
Gene
UniProtKB-ID: IP6K2_MOUSE, A0A0A6YXT7_MOUSE
UniprotKB: Q80V72, A0A0A6YXT7
UniParc: UPI0000D8B304, UPI0001549A3C
EMBL: AC173341, AC168054, BC039922
Ensembl: ENSMUSG00000032599, ENSMUSG00000106672
KO: mmu:76500
Nucleutide sequences
EMBL-CDS: AAH39922.1
Ensembl_TRS: ENSMUST00000201336, ENSMUST00000085018, ENSMUST00000192307
Protein sequencees
Ensembl_PRO: ENSMUSP00000082091, ENSMUSP00000144020, ENSMUSP00000142134
RefSeq: XP_006511918.1, NP_001366531.1, NP_001366532.1, XP_036011296.1, NP_001366530.1, XP_006511917.1, XP_006511919.1, NP_083910.2, XP_006511914.1, XP_006511916.1, NP_001366529.1
Others
UniRef100: UniRef100_A0A0A6YXT7, UniRef100_Q80V72
UniRef90: UniRef90_Q80V72, UniRef90_A0A0A6YXT7
UniRef50: UniRef50_A4IHU0, UniRef50_Q80V72
UniGene: Mm.276336, Mm.490338
CCDS: CCDS23537.1

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