| Type | Description |
|---|---|
| Definition | glutathione S-transferase kappa 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-23 13:04:00 | DsbA-L deficiency in T cells promotes diet-induced thermogenesis through suppressing IFN-gamma production. | 33436607 |
| 2020-10-10 13:03:00 | DsbA-L mediated renal tubulointerstitial fibrosis in UUO mice. | 32948751 |
| 2020-07-25 10:27:00 | DsbA-L modifies mitochondrial fission, linking alterations in mitochondrial dynamics during tubular injury in the pathogenesis of diabetic kidney disease. | 32167139 |
| 2020-02-15 13:04:00 | DsbA-L plays a critical protective role in renal ectopic fat deposition and lipid-related kidney injury in mice with diabetic nephropathy (DN) and patients with DN. The mechanisms might involve the inhibition of cholesterol synthesis through the inactivation of HMGCR and the promotion of lipolysis through the activation of ATGL and the subsequent reduction of lipid droplets accumulation in the kidney. | 30791996 |
| 2018-06-23 11:40:00 | DsbA-L prevents obesity-induced inflammation and insulin resistance by suppressing the mtDNA release-activated cGAS-cGAMP-STING pathway. | 29087318 |
| Type | IDs |
|---|---|
| Synonymous | 0610025I19Rik, AW260476, DsbA-L |
| Gene |
UniProtKB-ID:
GSTK1_MOUSE
UniprotKB:
Q9DCM2
UniParc:
UPI0000023316
EMBL:
AK002661,
BC058163,
AY279096
Ensembl:
ENSMUSG00000029864
KO:
mmu:76263
|
| Nucleutide sequences |
EMBL-CDS:
AAH58163.1,
AAP20655.1,
BAB22268.1
Ensembl_TRS:
ENSMUST00000031897
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000031897
RefSeq:
NP_083831.1
|
| Others |
UniRef100:
UniRef100_Q9DCM2
UniRef90:
UniRef90_Q9DCM2
UniRef50:
UniRef50_Q9DCM2
UniGene:
Mm.267014
CCDS:
CCDS20063.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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