| Type | Description |
|---|---|
| Definition | carbonic anhydrase 4 |
| Date | Results | Publications |
|---|---|---|
| 2020-04-18 12:36:00 | carbonic anhydrase 1 (CA1) and CA4 were identified as potential biomarkers of Colon adenocarcinoma due to their predictive roles in diagnosis and prognosis, and the results were further confirmed by a series of analyses. | 32031891 |
| 2020-02-01 10:04:00 | highest susceptibility effect was noticed in the rs2274328 of carbonic anhydrase VI (AA vs CC) model (d = 0.18; 95% CI (confidence interval): -1.77, 2.13), but this effect was not significant [meta-analysis] | 31895503 |
| 2019-05-04 12:46:00 | This study analyzed the direct interaction between CAIV and the two Monocarboxylate transporters (MCTs) chaperones basigin (CD147) and embigin (GP70). In human CD147, binding of CAIV was mediated by the negatively charged Glu-73. | 30446621 |
| 2017-07-01 12:16:00 | CA4 is a novel tumour suppressor in Colorectal cancer through the inhibition of the Wnt signalling pathway by targeting the WTAP-WT1-TBL1 axis. CA4 methylation may serve as an independent biomarker for the recurrence of Colorectal cancer . | 26071132 |
| 2014-09-06 11:00:00 | Carbonic anhydrase 4 is lost in papillary thyroid carcinoma but not thyroid nodules | 24880201 |
| Type | IDs |
|---|---|
| Synonymous | CAIV, Car4, RP17 |
| Gene |
UniProtKB-ID:
CAH4_HUMAN
UniprotKB:
P22748
UniParc:
UPI00017A79BC,
UPI000004EC91
EMBL:
L10955,
M83670,
AK289715,
L10953,
AK298710,
L10951,
CR541766,
BC069649,
CH471109,
AC025048,
BC057792,
BC074768,
L10954
Ensembl:
ENSG00000167434
KO:
hsa:762
|
| Nucleutide sequences |
EMBL-CDS:
AAA35626.1,
BAF82404.1,
EAW94362.1,
AAH69649.1,
AAH74768.1,
AAA35625.1,
AAH57792.1,
AAA35630.1,
CAG46565.1,
BAG60866.1
Ensembl_TRS:
ENST00000300900,
ENST00000586876
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000467465,
ENSP00000300900
RefSeq:
XP_016880501.1,
NP_000708.1,
XP_005257696.1,
XP_011523485.1
|
| Others |
UniRef100:
UniRef100_P22748
UniRef90:
UniRef90_P22748
UniRef50:
UniRef50_P22748
UniGene:
Hs.89485
CCDS:
CCDS11624.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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