| Type | Description |
|---|---|
| Definition | Wnt family member 9A |
| Date | Results | Publications |
|---|---|---|
| 2019-09-21 11:56:00 | Compared with normal tubular cells, tubular cells of humans with a variety of nephropathies expressed high levels of Wnt9a that colocalized with p16(INK4A). Wnt9a expression level correlated with the extent of renal fibrosis, decline of eGFR, and expression of p16(INK4A).In a proximal tubular epithelial cell line and primary renal tubular cells, Wnt9a upregulated p16(INK4A). | 29440280 |
| 2019-07-13 12:35:00 | We demonstrate that the epidermal growth factor receptor (EGFR) is required as a cofactor for Wnt9a-Fzd9b signalling. EGFR-mediated phosphorylation of one tyrosine residue on the Fzd9b intracellular tail in response to Wnt9a promotes internalization of the Wnt9a-Fzd9b-LRP signalosome and subsequent signal transduction | 31110287 |
| 2017-09-30 12:14:00 | This manipulation increased one type of sensory hair cell (tall HCs) at the expense of another (short HCs) that is usually located furthest from the Wnt9a source. The extraneous tall HCs that replaced short HCs showed some physiological properties and neuronal connections consistent with a fate switch. | 28821654 |
| 2016-10-22 11:31:00 | Inhibition of WNT signaling by the PORCN inhibitor WNT974 reduced metastatic spread of UM-SCC cells, especially in UM-SCCs with Notch1 deficiency. | 27117272 |
| 2015-11-28 10:32:00 | expression is enhanced in idiopathic carpal tunnel syndrome | 26174360 |
| Type | IDs |
|---|---|
| Synonymous | WNT14 |
| Gene |
UniProtKB-ID:
WNT9A_HUMAN,
D9ZGG3_HUMAN
UniprotKB:
O14904,
D9ZGG3
UniParc:
UPI000005104B
EMBL:
BC113431,
AL360269,
HM015601,
BC111960,
AF028702,
AB060283,
CH471098
Ensembl:
ENSG00000143816
KO:
hsa:7483
|
| Nucleutide sequences |
EMBL-CDS:
BAB61051.1,
AAC39550.1,
AAI11961.1,
AAI13432.1,
EAW69821.1,
ADL14522.1
Ensembl_TRS:
ENST00000272164
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000272164
RefSeq:
NP_003386.1,
XP_011542573.1
|
| Others |
UniRef100:
UniRef100_O14904
UniRef90:
UniRef90_O14904
UniRef50:
UniRef50_O14904
UniGene:
Hs.149504
CCDS:
CCDS31045.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员