Type | Description |
---|---|
Definition | VRK serine/threonine kinase 2 |
Date | Results | Publications |
---|---|---|
2019-09-28 11:04:00 | our work reveals the regulation of dysbindin by VRK2, providing the association of these two proteins, which are commonly implicated in schizophrenia | 30062698 |
2019-02-23 11:58:00 | Structural characterization of human vaccinia-related kinases, VRK1 and VRK2, bound to small-molecule inhibitors, has been reported. | 28790404 |
2019-02-23 11:47:00 | a novel insight into the oncogenic activity of VRK2-Akt complexes in the lysosomes via modulation of autophagy | 29872222 |
2018-09-01 11:15:00 | VRK2 is suggested as a candidate gene for neurological disorders through its role in signaling pathway, the neuronal loss and stress response. | 29100046 |
2018-05-26 11:22:00 | GSK3beta may inhibit VRK2 catalytic activity by disrupting its flexibility. The inhibition of VRK2 catalytic activity by GSK3beta may also inhibit VRK2-induced degradation of TRiC, which could suppress polyQ-expanded Htt aggregation. | 27377031 |
Type | IDs |
---|---|
Gene |
UniProtKB-ID:
VRK2_HUMAN,
A8K9L2_HUMAN
UniprotKB:
Q86Y07,
A8K9L2
UniParc:
UPI00001D8A7C,
UPI00000622D0,
UPI00000622CE,
UPI000013D498,
UPI0000D4EA29,
UPI00006A781D
EMBL:
AK223540,
CH471053,
BC027854,
AC073215,
AC068193,
AY228370,
AC007250,
AY228367,
AY228372,
AY228371,
AJ512204,
AY228368,
AK292727,
AK296611,
AY228369,
AB000450
Ensembl:
ENSG00000028116
KO:
hsa:7444
|
Nucleutide sequences |
EMBL-CDS:
AAO73052.1,
AAH27854.1,
AAX93262.1,
BAD97260.1,
AAY14648.1,
BAG59222.1,
AAO73050.1,
EAX00066.1,
AAO73048.1,
EAX00068.1,
AAO73049.1,
CAD54446.2,
AAO73047.1,
EAX00067.1,
EAX00064.1,
EAX00062.1,
BAA19109.1,
AAO73051.1,
AAY15019.1,
BAF85416.1
Ensembl_TRS:
ENST00000435505,
ENST00000412104,
ENST00000340157,
ENST00000648897,
ENST00000417641,
ENST00000440705
|
Protein sequencees |
Ensembl_PRO:
ENSP00000402375,
ENSP00000408002,
ENSP00000342381,
ENSP00000497378,
ENSP00000404156,
ENSP00000398323
RefSeq:
NP_001123954.1,
NP_006287.2,
NP_001123955.1,
XP_006712156.1,
NP_001123952.1,
NP_001275767.1,
NP_001275766.1,
XP_016860348.1,
XP_016860355.1,
NP_001123953.1,
XP_006712154.1,
XP_011531394.1,
NP_001275765.1,
XP_016860351.1,
XP_016860354.1,
NP_001275768.1,
XP_016860350.1,
XP_016860349.1,
XP_016860347.1,
XP_006712155.1,
XP_006712153.1,
XP_005264597.1,
XP_016860352.1
|
Others |
UniRef100:
UniRef100_Q86Y07,
UniRef100_A8K9L2
UniRef90:
UniRef90_Q86Y07,
UniRef90_Q86Y07-2
UniRef50:
UniRef50_Q86Y07-2,
UniRef50_Q86Y07
UniGene:
Hs.744058
CCDS:
CCDS1859.1,
CCDS46291.1,
CCDS46292.1
|
{{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
---|---|---|---|---|---|---|---|---|
Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
暂无数据
排名 | 科研单位 | 文献 |
---|---|---|
{{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
排名 | 研究人员 | 文献 |
---|---|---|
{{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员