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74155 Errfi1

74155

Errfi1

ERBB receptor feedback inhibitor 1

protein-coding

Mus musculus

基因描述

Type Description
Definition ERBB receptor feedback inhibitor 1

研究结论

Date Results Publications
2019-12-14 10:39:00 cPLA2 is a novel target of tumor suppressor gene, Mig-6, in the uterus. 30773264
2019-10-05 10:05:00 Mig6 regulates the production of inflammatory mediators (TNF-alpha, il-1beta) through inhibiting the over activation of EGFR. 29336487
2019-01-19 11:48:00 Study in mouse model where Mig-6 is specifically ablated only in the epithelial cells of the uterus suggests that endometrial epithelial cell proliferation is regulated by progesterone (P4) mediated Mig-6 inhibition of AKT phosphorylation, uncovering new mechanisms of P4 action. 29843645
2018-10-13 10:41:00 Study showed that Mig-6 has an important function of tumor suppressor via inhibition of phosphorylation in uterine epithelial cells, and the antitumor effects of progesterone are mediated by the endometrial stroma. 28925396
2018-07-07 10:45:00 Mig-6 deficiency promotes the development of Kras(G12D)-induced lung adenoma through reducing the cell apoptosis in Kras(G12D) mouse lungs partially by activating the ErbB4 pathway. 29191600

名称对应

Type IDs
Synonymous 1300002F13Rik, AI788755, Mig-6, Mig6, RALT
Gene
UniProtKB-ID: ERRFI_MOUSE, Q3TK48_MOUSE
UniprotKB: Q99JZ7, Q3TK48
UniParc: UPI0000023064
EMBL: AK166791, BC005546, BC057646, AK167156
Ensembl: ENSMUSG00000028967
KO: mmu:74155
Nucleutide sequences
EMBL-CDS: AAH05546.1, AAH57646.1, BAE39297.1, BAE39021.1
Ensembl_TRS: ENSMUST00000030811, ENSMUST00000073600
Protein sequencees
Ensembl_PRO: ENSMUSP00000030811, ENSMUSP00000073285
RefSeq: NP_598514.1, NP_001343252.1
Others
UniRef100: UniRef100_Q99JZ7
UniRef90: UniRef90_P05432-2
UniRef50: UniRef50_P05432-2
UniGene: Mm.318841
CCDS: CCDS18974.1

全选

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研究热度

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