| Type | Description |
|---|---|
| Definition | LYR motif containing 1 |
| Date | Results | Publications |
|---|---|---|
| 2016-10-22 10:44:00 | knockdown of LYRM1 induced mitochondrial impairment in P19 cells during differentiation, which was reflected by decreased ATP synthesis, lower MMP and increased levels. | 26759027 |
| 2015-09-05 10:12:00 | FCCP-induced mitochondrial dysfunction and insulin resistance are ameliorated by knockdown of LYRM1 | 24771405 |
| 2013-02-02 10:53:00 | alpha-LA protects 3T3-L1 adipocytes from LYRM1-induced insulin resistance partially via its capacity to restore mitochondrial function and/or increase phosphorylation of IRS-1 and Akt. | 22820890 |
| 2012-07-21 11:25:00 | Knockdown of the Lyrm1 gene in adipocytes resulted in dramatically increased cellular ATP production, mitochondrial membrane potentials and levels Ucp2 mRNA, while levels were significantly decreased. | 22249831 |
| 2012-03-31 10:45:00 | results suggest that the expression of LYRM1 mRNA is affected by a variety of factors that are related to insulin sensitivity; LYRM1 may be an important mediator in the development of obesity-related insulin resistance | 22110480 |
| Type | IDs |
|---|---|
| Synonymous | 1110065L10Rik, 2310004B22Rik, 4930404J24Rik |
| Gene |
UniProtKB-ID:
LYRM1_MOUSE
UniprotKB:
Q9CQB7
UniParc:
UPI0000023631
EMBL:
AK157931,
AK009135,
BC011339,
AK015083
Ensembl:
ENSMUSG00000030922
KO:
mmu:73919
|
| Nucleutide sequences |
EMBL-CDS:
BAB26096.1,
BAB29706.1,
AAH11339.1,
BAE34269.1
Ensembl_TRS:
ENSMUST00000054440,
ENSMUST00000208424,
ENSMUST00000207270,
ENSMUST00000106518,
ENSMUST00000106517,
ENSMUST00000208202,
ENSMUST00000106516
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000146699,
ENSMUSP00000146648,
ENSMUSP00000102127,
ENSMUSP00000146841,
ENSMUSP00000102128,
ENSMUSP00000051616,
ENSMUSP00000102126
RefSeq:
NP_001272890.1,
XP_006508299.1,
XP_006508297.1,
XP_036009372.1,
XP_006508303.1,
XP_006508301.1,
XP_006508302.1,
NP_001272889.1,
NP_083886.1,
XP_006508306.1,
XP_036009373.1,
XP_006508300.1,
NP_001272888.1,
XP_006508307.1,
XP_006508298.1,
XP_006508304.1
|
| Others |
UniRef100:
UniRef100_Q9CQB7
UniRef90:
UniRef90_Q9CQB7
UniRef50:
UniRef50_O43325
UniGene:
Mm.46381,
Mm.291751
CCDS:
CCDS21790.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 26759027 |
J. Bioenerg. Biomembr. Yu-Mei Chen , Xing Li , Gui-Xian Song , Ming Liu , Yi Fan , Li-Jie Wu , Hua Li , Qi-Jun Zhang , Yao-Qiu Liu , Ling-Mei Qian |
2016-02-01 | - |
| 24771405 |
Cell Biochem. Biophys. Min Zhang , Zhen-Ying Qin , Yong-mei Dai , Yu-Mei Wang , Guan-zhong Zhu , Ya-Ping Zhao , Chen-Bo Ji , Jin-Gai Zhu , Chun-Mei Shi , Jie Qiu , Xin-Guo Cao , Xi-Rong Guo |
2014-09-01 |
Lyrm1
|
| 22820890 |
J. Bioenerg. Biomembr. Zhen-Ying Qin , Min Zhang , Xi-Rong Guo , Yu-Mei Wang , Guan-Zhong Zhu , Yu-Hui Ni , Ya-Ping Zhao , Jie Qiu , Chun-Zhao Kou , Rui Qin , Xin-Guo Cao |
2012-10-01 | - |
| 22249831 |
Effects of Lyrm1 knockdown on mitochondrial function in 3 T3-L1 murine adipocytes. J. Bioenerg. Biomembr. Guan-Zhong Zhu , Min Zhang , Chun-Zhao Kou , Yu-Hui Ni , Chen-Bo Ji , Xin-Guo Cao , Xi-Rong Guo |
2012-02-01 | - |
| 22110480 |
Exp Diabetes Res Min Zhang , Hai-Ming Zhao , Zhen-Ying Qin , Rui Qin , Xiao-Hui Chen , Ya-Ping Zhao , Chun-Mei Zhang , Chun-Lin Gao , Chun Zhu , Chen-Bo Ji , Xin-Guo Cao , Xi-Rong Guo |
2012-01-01 |
Lyrm1
|
| 21267068 |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. Graciana Diez-Roux , Sandro Banfi , Marc Sultan , Lars Geffers , Santosh Anand , David Rozado , Alon Magen , Elena Canidio , Massimiliano Pagani , Ivana Peluso , Nathalie Lin-Marq , Muriel Koch , Marchesa Bilio , Immacolata Cantiello , Roberta Verde , Cristian De Masi , Salvatore A Bianchi , Juliette Cicchini , Elodie Perroud , Shprese Mehmeti , Emilie Dagand , Sabine Schrinner , Asja Nürnberger , Katja Schmidt , Katja Metz , Christina Zwingmann , Norbert Brieske , Cindy Springer , Ana Martinez Hernandez , Sarah Herzog , Frauke Grabbe , Cornelia Sieverding , Barbara Fischer , Kathrin Schrader , Maren Brockmeyer , Sarah Dettmer , Christin Helbig , Violaine Alunni , Marie-Annick Battaini , Carole Mura , Charlotte N Henrichsen , Raquel Garcia-Lopez , Diego Echevarria , Eduardo Puelles , Elena Garcia-Calero , Stefan Kruse , Markus Uhr , Christine Kauck , Guangjie Feng , Nestor Milyaev , Chuang Kee Ong , Lalit Kumar , MeiSze Lam , Colin A Semple , Attila Gyenesei , Stefan Mundlos , Uwe Radelof , Hans Lehrach , Paolo Sarmientos , Alexandre Reymond , Duncan R Davidson , Pascal Dollé , Stylianos E Antonarakis , Marie-Laure Yaspo , Salvador Martinez , Richard A Baldock , Gregor Eichele , Andrea Ballabio |
2011-01-18 | - |
| 18799693 |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. Gwenn M Hansen , Diane C Markesich , Michael B Burnett , Qichao Zhu , Karen M Dionne , Lizabeth J Richter , Richard H Finnell , Arthur T Sands , Brian P Zambrowicz , Alejandro Abuin |
2008-10-01 |
Gm11335,
Gm17762,
A930017K11Rik,
BC028777,
Gm13999,
Gm11696,
Gm12359,
Gm10589,
D030047H15Rik,
Gm10856,
Gm10685,
Gm10062,
Gm10433,
Gm10648,
Gm10840,
Gm15441,
Gm10684,
Gm9900,
Gm10822,
Gm10687,
Gm11744,
Gm10747,
Arih2os,
B230344G16Rik,
Fmr1os,
Tmem51os1,
Gm14488,
Gm13033,
Gm10789,
Gm10615,
Gm1976,
Gm9967,
Gm9917,
Gm1974,
Gm11496,
Gm13580,
Gm2085,
Gm2183,
Gm2245,
Tbx3os1,
Gm12980,
Gm2329,
Lncenc1,
Gm2381,
Snhg12,
Gm2479,
Gm12942,
Gm2529,
Gm2533,
Rpl30-ps7,
Rsf1os2,
Gm2695,
2810416G20Rik,
Rpl30-ps6,
Gm2773,
Gm2788,
Dynlt1f,
Gm9793,
Gm2885,
Gm2920,
Gm15506,
Gm11627,
Gm10518,
Gm13496,
Gm3134,
Gm12827,
Gm3143,
Gm10144,
Ahnak2,
Gm3196,
Gm13242,
Gm3325,
Gm13247,
Gm10863,
Gm13157,
4930522L14Rik,
Gm3552,
Gm15226,
Gm3604,
Gm3643,
BC005561,
Gm3716,
2810410L24Rik,
Gm10282,
Gm3839,
Nhsl2,
4732419C18Rik,
Gm3906,
Gm3973,
Gm4013,
Apol7d,
Gm12057,
Gm10489,
Rex2,
1110002L01Rik,
Gm4189,
Gm4204,
4632428C04Rik,
9130023H24Rik
|
| 18614015 |
A mitochondrial protein compendium elucidates complex I disease biology. Cell David J Pagliarini , Sarah E Calvo , Betty Chang , Sunil A Sheth , Scott B Vafai , Shao-En Ong , Geoffrey A Walford , Canny Sugiana , Avihu Boneh , William K Chen , David E Hill , Marc Vidal , James G Evans , David R Thorburn , Steven A Carr , Vamsi K Mootha |
2008-07-11 |
Acacb,
Hscb,
Gadd45gip1,
Lars2,
Acad11,
Chchd10,
Nt5dc3,
Slc25a41,
Nt5m,
Cyp27a1,
Acly,
Ndufb11,
Gldc,
Rexo2,
Rars,
Aldh6a1,
Slc25a47,
Rdh14,
Ppif,
Ldhal6b,
Me2,
Glyat,
Slc25a45,
Acaca,
Nt5c3,
Mrpl10,
Mrpl41,
Mrpl30,
Aldh1l1,
Mthfs,
Shmt2,
Atic,
Mthfd1,
Mat2b,
Fam210a,
Gpt2,
Lyrm2,
Rdh13,
Mtrf1l,
Atad3a,
Rars2,
Sccpdh,
Me3,
Maob,
Dut,
Cyp11b1,
Fdps,
Akr7a5,
Msra,
Krt5,
Cox6b1,
Qdpr,
Acat1,
Acat2,
Aldh7a1,
Pcca,
Etfb,
Etfa,
Nudt19,
Acadl,
Acadm,
Acadvl,
Acaa1a,
Acads,
Aco1,
Aco2,
Prosc,
Afg3l1,
Adsl,
Agxt,
Ak2,
Ak4,
Akap1,
Alas1,
Alas2,
Abcd1,
Aldh2,
Aldh3a2,
Gfer,
Acsm1,
Slc25a4,
Slc25a5,
Prdx3,
Prdx6,
Mrps2,
Arg2,
Rhoa,
Atp5a1,
Atp5b,
Atp5c1,
Atp5f1,
Atp5g1,
Atp5j,
Atp5k,
Atpif1,
Auh,
Akr1b7,
Bad,
Bak1
|
| 17967808 |
EUCOMM--the European conditional mouse mutagenesis program. Brief Funct Genomic Proteomic Roland H Friedel , Claudia Seisenberger , Cornelia Kaloff , Wolfgang Wurst |
2007-09-01 |
Gm11696,
Gm10589,
Apela,
Gm10822,
Gm2085,
Gm2312,
Lncenc1,
Gm2381,
Gm2659,
Gm2679,
Dynlt1c,
Gm3134,
Gm3143,
Gm3236,
Gm3574,
Gm3581,
Gm3718,
Gm3859,
Gm3905,
Gm3952,
Gm3957,
Gm3973,
Gm12057,
Rex2,
Gm4218,
Gm4225,
Gm16476,
Gm4407,
Gm14410,
Gm4420,
Gm14005,
1300002E11Rik,
Gm4532,
Srcap,
Gm17789,
Gm10751,
Gm14321,
0610009E02Rik,
Gm12758,
Gm11532,
Phactr4,
Rusc2,
AK010878,
Gm10778,
5830417I10Rik,
Mir1902,
Gm15270,
Gm11767,
Ino80dos,
Bsdc1,
Gm7645,
Gm20590,
Slc44a1,
Gm15545,
Gm17292,
2900009J06Rik,
Kifc1,
Gm13150,
Gm19426,
Gm19428,
Gm19474,
Gm14963,
Gm19565,
Gm19592,
Gm12588,
Snhg4,
Gm19702,
Gm19705,
Platr22,
Nuggc,
Zfp534,
Gm19860,
Gm11725,
Gm19876,
Gm19889,
Gm16201,
Gm13056,
Tnfsf13os,
Gm19925,
Gm19976,
Gm20014,
Gm16740,
Gm20039,
Gm20045,
AU020206,
Ccdc170,
Trp53cor1,
Gm20266,
Gm20324,
Zfp518b,
Gm14401,
AI480526,
Pds5b,
Ube3c,
Gm21297,
Akap9,
Gm29724,
Itfg2,
Parp11
|
| 16141072 |
The transcriptional landscape of the mammalian genome. Science P Carninci , T Kasukawa , S Katayama , J Gough , M C Frith , N Maeda , R Oyama , T Ravasi , B Lenhard , C Wells , R Kodzius , K Shimokawa , V B Bajic , S E Brenner , S Batalov , A R R Forrest , M Zavolan , M J Davis , L G Wilming , V Aidinis , J E Allen , A Ambesi-Impiombato , R Apweiler , R N Aturaliya , T L Bailey , M Bansal , L Baxter , K W Beisel , T Bersano , H Bono , A M Chalk , K P Chiu , V Choudhary , A Christoffels , D R Clutterbuck , M L Crowe , E Dalla , B P Dalrymple , B de Bono , G Della Gatta , D di Bernardo , T Down , P Engstrom , M Fagiolini , G Faulkner , C F Fletcher , T Fukushima , M Furuno , S Futaki , M Gariboldi , P Georgii-Hemming , T R Gingeras , T Gojobori , R E Green , S Gustincich , M Harbers , Y Hayashi , T K Hensch , N Hirokawa , D Hill , L Huminiecki , M Iacono , K Ikeo , A Iwama , T Ishikawa , M Jakt , A Kanapin , M Katoh , Y Kawasawa , J Kelso , H Kitamura , H Kitano , G Kollias , S P T Krishnan , A Kruger , S K Kummerfeld , I V Kurochkin , L F Lareau , D Lazarevic , L Lipovich , J Liu , S Liuni , S McWilliam , M Madan Babu , M Madera , L Marchionni , H Matsuda , S Matsuzawa , H Miki , F Mignone , S Miyake , K Morris , S Mottagui-Tabar , N Mulder , N Nakano , H Nakauchi , P Ng , R Nilsson , S Nishiguchi , S Nishikawa , F Nori , O Ohara , Y Okazaki , V Orlando , K C Pang , W J Pavan , G Pavesi , G Pesole , N Petrovsky , S Piazza , J Reed , J F Reid , B Z Ring , M Ringwald , B Rost , Y Ruan , S L Salzberg , A Sandelin , C Schneider , C Schönbach , K Sekiguchi , C A M Semple , S Seno , L Sessa , Y Sheng , Y Shibata , H Shimada , K Shimada , D Silva , B Sinclair , S Sperling , E Stupka , K Sugiura , R Sultana , Y Takenaka , K Taki , K Tammoja , S L Tan , S Tang , M S Taylor , J Tegner , S A Teichmann , H R Ueda , E van Nimwegen , R Verardo , C L Wei , K Yagi , H Yamanishi , E Zabarovsky , S Zhu , A Zimmer , W Hide , C Bult , S M Grimmond , R D Teasdale , E T Liu , V Brusic , J Quackenbush , C Wahlestedt , J S Mattick , D A Hume , C Kai , D Sasaki , Y Tomaru , S Fukuda , M Kanamori-Katayama , M Suzuki , J Aoki , T Arakawa , J Iida , K Imamura , M Itoh , T Kato , H Kawaji , N Kawagashira , T Kawashima , M Kojima , S Kondo , H Konno , K Nakano , N Ninomiya , T Nishio , M Okada , C Plessy , K Shibata , T Shiraki , S Suzuki , M Tagami , K Waki , A Watahiki , Y Okamura-Oho , H Suzuki , J Kawai , Y Hayashizaki , FANTOM Consortium , RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) |
2005-09-02 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员