Type | Description |
---|---|
Definition | UDP glucuronosyltransferase family 2 member B10 |
Date | Results | Publications |
---|---|---|
2019-09-21 11:47:00 | a cis-regulatory SNP for human UGT2B10 | 29431853 |
2019-02-16 10:51:00 | The high prevalence of a UGT2B10 splice variant among African Americans results in lower 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL), - N-glucuronidation but only a small decrease in total NNAL glucuronidation. Therefore, despite the significant contribution of UGT2B10 to NNAL- N-glucuronidation, the UGT2B10 genotype does not play a large role in NNAL detoxication. | 29460622 |
2018-11-17 10:05:00 | UGT2B10 was for the first time identified as an N-glucosidation enzyme. Generated N-glucosides were excreted primarily by the BCRP transporter. | 29691239 |
2018-11-10 12:22:00 | A significant contribution of AS in the regulation of UGT2B10 expression in the liver. | 29438977 |
2018-04-14 10:05:00 | UGT2B10 activity or genotype should be considered when using cotinine as a tobacco exposure biomarker, particularly in populations such as African American with high frequencies of UGT2B10 nonfunctional variants. | 28264876 |
Type | IDs |
---|---|
Synonymous | UDPGT2B10 |
Gene |
UniProtKB-ID:
UDB10_HUMAN
UniprotKB:
P36537
UniParc:
UPI0000137A96,
UPI00004804DA
EMBL:
CH471057,
BC113649,
AK298432,
AK292738,
X63359,
AC021146
Ensembl:
ENSG00000109181,
ENSG00000275190
KO:
hsa:7365
|
Nucleutide sequences |
EMBL-CDS:
CAA44961.1,
BAF85427.1,
EAX05577.1,
BAG60653.1,
AAI13650.1
Ensembl_TRS:
ENST00000265403,
ENST00000615213,
ENST00000627047,
ENST00000458688
|
Protein sequencees |
Ensembl_PRO:
ENSP00000265403,
ENSP00000478760,
ENSP00000486876,
ENSP00000413420
RefSeq:
NP_001138239.1,
XP_016864074.1,
NP_001066.1,
NP_001277020.1
|
Others |
UniRef100:
UniRef100_P36537
UniRef90:
UniRef90_P36537
UniRef50:
UniRef50_P16662
UniGene:
Hs.201634
CCDS:
CCDS75136.1,
CCDS75135.1
|
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