| Type | Description |
|---|---|
| Definition | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 |
| Date | Results | Publications |
|---|---|---|
| 2017-05-06 14:46:00 | this study has identified a new role for Parvin and alphaPix downstream of the integrin-ILK signaling axis for mammary epithelial cell differentiation. | 27019299 |
| 2016-04-02 10:42:00 | Enforced expression of miR-135a in highly tumorigenic cancer stem cells strongly inhibited tumorigenesis by repressing the miR-135a direct target gene Arhgef6. | 25639612 |
| 2014-06-14 10:58:00 | Results indicate Arhgef6 (alphaPIX) as a regulator of thymocyte migration and subsequent arrest that is linked to positive selection. | 24591366 |
| 2013-03-23 11:58:00 | alphaPIX and GIT2 are required for neuronal differentiation. | 22554054 |
| 2012-04-28 10:35:00 | suggest that imbalance in activity of different Rho GTPases may underlie altered neuronal connectivity and impaired synaptic function and cognition in alphaPix/Arhgef6 knockout mice | 21989057 |
| Type | IDs |
|---|---|
| Synonymous | 1600028C08Rik, 1700038J06Rik, 4930592P22Rik, alpha-PIX |
| Gene |
UniProtKB-ID:
ARHG6_MOUSE,
F6WMJ3_MOUSE
UniprotKB:
Q8K4I3,
F6WMJ3
UniParc:
UPI0001BE8104,
UPI0000028C76
EMBL:
AF393831,
AK040468,
AL672128,
AL672106
Ensembl:
ENSMUSG00000031133
KO:
mmu:73341
|
| Nucleutide sequences |
EMBL-CDS:
AAM94903.1,
BAC30599.1
Ensembl_TRS:
ENSMUST00000033468
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000033468
RefSeq:
XP_006528376.1,
XP_030107372.1,
XP_030107368.1,
XP_030107371.1,
XP_030107369.1,
XP_036018002.1,
XP_006528377.1,
NP_690014.2,
XP_006528378.1,
NP_001345502.1,
XP_030107370.1
|
| Others |
UniRef100:
UniRef100_Q8K4I3
UniRef90:
UniRef90_Q8K4I3
UniRef50:
UniRef50_Q15052
UniGene:
Mm.261443
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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