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72584 Cul4b

72584

Cul4b

cullin 4B

protein-coding

Mus musculus

基因描述

Type Description
Definition cullin 4B

研究结论

Date Results Publications
2020-06-27 11:56:00 Aryl hydrocarbon receptor (AhR) functions as a substrate receptor for Cullin 4b (Cul4b)-mediated peroxisome proliferator-activated receptor gamma (PPARgamma) degradation in mouse 3T3-L1 cells. 31653699
2020-04-11 10:56:00 Study in Cul4b knockout mice showed that the loss of embryonic Cul4b affects the growth of the inner cell mass in vitro and delays epiblast development during the gastrulation period at E6.5~E7.5 in vivo, as highlighted by the absence of the epiblastic transcription factor Brachyury from E6.5~E7.5. 31260508
2020-02-15 12:55:00 demonstrate that the enhanced growth and metastasis of transplanted tumor cells in hematopoietic or myeloid cell-specific Cul4b knockout recipient mice is mediated by increased production of IL-6 in myeloid-derived suppressive cells 31235785
2019-05-11 12:20:00 CUL4B level mediates HOX gene expression via histone H2A ubiquitination. Aberrant CUL4B-mediated H2AK119ub1 level may be a risk factor for neural tube defects. 30992047
2019-03-09 11:07:00 High CUL4B expression promotes gastric cancer invasion and metastasis. 29106389

名称对应

Type IDs
Synonymous 2700050M05Rik, AA409770, CUL-4B, mKIAA0695
Gene
UniProtKB-ID: CUL4B_MOUSE, Q3TP81_MOUSE
UniprotKB: A2A432, Q3TP81
UniParc: UPI0001D322ED, UPI0000DBEDD2, UPI00005B20A9
EMBL: AK164640, AY330868, CH466570, BC004026, BC010347, AK012410, AL513356, AK160998, AK032701, AB093259
Ensembl: ENSMUSG00000031095
KO: mmu:72584
Nucleutide sequences
EMBL-CDS: EDL29019.1, BAC41443.3, BAE36141.1, AAP84984.1, BAC27992.1, AAH10347.1, AAH04026.1, CAM17145.1, BAB28222.2, BAE37856.1
Ensembl_TRS: ENSMUST00000115118, ENSMUST00000050083
Protein sequencees
Ensembl_PRO: ENSMUSP00000110771, ENSMUSP00000059276
RefSeq: NP_082564.3, NP_001103612.1
Others
UniRef100: UniRef100_A2A432, UniRef100_A0A4X1W6P8
UniRef90: UniRef90_Q13620, UniRef90_A2A432
UniRef50: UniRef50_Q13620
UniGene: Mm.327675
CCDS: CCDS40948.1

全选

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