| Type | Description |
|---|---|
| Definition | Mtr4 exosome RNA helicase |
| Date | Results | Publications |
|---|---|---|
| 2017-09-16 12:45:00 | Skiv2l2 knockdown cells accumulated replication-dependent histone mRNAs, among other RNAs, that could impede mitotic progression and indirectly trigger differentiation. | 28351885 |
| 2017-06-24 10:10:00 | Study reports that the noncoding RNA processing activity of RNA exosome, a 3'-5' RNA exonuclease, controls sense and antisense strand DNA mutagenesis, and prevents an increased asymmetric mutagenesis burden using a mechanism that relies on the unexpected DNA/RNA hybrid unwinding activities of the Mtr4 and senataxin RNA helicases. | 28431250 |
| 2015-10-31 11:36:00 | Results identify novel role for Mtr4 in targeting the 5' leader sequences of microRNAs for degradation. | 24926684 |
| 2012-01-14 11:58:00 | SKIV2L2 is an RNA-binding protein localized to the nucleus in the round spermatids of mice | 21467735 |
| Type | IDs |
|---|---|
| Synonymous | 2610528A15Rik, Skiv2l2, mKIAA0052 |
| Gene |
UniProtKB-ID:
MTREX_MOUSE
UniprotKB:
Q9CZU3
UniParc:
UPI0000021CEB
EMBL:
AK012158,
BC029230
Ensembl:
ENSMUSG00000016018
KO:
mmu:72198
|
| Nucleutide sequences |
EMBL-CDS:
BAB28066.1,
AAH29230.1
Ensembl_TRS:
ENSMUST00000022281
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000022281
RefSeq:
XP_036014071.1,
NP_082427.1
|
| Others |
UniRef100:
UniRef100_Q9CZU3
UniRef90:
UniRef90_P42285
UniRef50:
UniRef50_P42285
UniGene:
Mm.291029
CCDS:
CCDS26778.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 32325033 |
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Cell Syst Reza Pourhaghighi , Peter E A Ash , Sadhna Phanse , Florian Goebels , Lucas Z M Hu , Siwei Chen , Yingying Zhang , Shayne D Wierbowski , Samantha Boudeau , Mohamed T Moutaoufik , Ramy H Malty , Edyta Malolepsza , Kalliopi Tsafou , Aparna Nathan , Graham Cromar , Hongbo Guo , Ali Al Abdullatif , Daniel J Apicco , Lindsay A Becker , Aaron D Gitler , Stefan M Pulst , Ahmed Youssef , Ryan Hekman , Pierre C Havugimana , Carl A White , Benjamin C Blum , Antonia Ratti , Camron D Bryant , John Parkinson , Kasper Lage , Mohan Babu , Haiyuan Yu , Gary D Bader , Benjamin Wolozin , Andrew Emili |
2020-04-22 | - |
| 30595499 |
Lysosomal Signaling Licenses Embryonic Stem Cell Differentiation via Inactivation of Tfe3. Cell Stem Cell Florian Villegas , Daphné Lehalle , Daniela Mayer , Melanie Rittirsch , Michael B Stadler , Marietta Zinner , Daniel Olivieri , Pierre Vabres , Laurence Duplomb-Jego , Eveline S J M De Bont , Yannis Duffourd , Floor Duijkers , Magali Avila , David Geneviève , Nada Houcinat , Thibaud Jouan , Paul Kuentz , Klaske D Lichtenbelt , Christel Thauvin-Robinet , Judith St-Onge , Julien Thevenon , Koen L I van Gassen , Mieke van Haelst , Silvana van Koningsbruggen , Daniel Hess , Sebastien A Smallwood , Jean-Baptiste Rivière , Laurence Faivre , Joerg Betschinger |
2019-02-07 | - |
| 30196744 |
ATG5 is required for B cell polarization and presentation of particulate antigens. Autophagy Florent Arbogast , Johan Arnold , Philippe Hammann , Lauriane Kuhn , Johana Chicher , Diane Murera , Justine Weishaar , Sylviane Muller , Jean-Daniel Fauny , Frédéric Gros |
2019-02-01 | - |
| 30550785 |
Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors. Cell Hyeonwoo Kim , Christiane D Wrann , Mark Jedrychowski , Sara Vidoni , Yukiko Kitase , Kenichi Nagano , Chenhe Zhou , Joshua Chou , Virginia-Jeni A Parkman , Scott J Novick , Timothy S Strutzenberg , Bruce D Pascal , Phuong T Le , Daniel J Brooks , Alexander M Roche , Kaitlyn K Gerber , Laura Mattheis , Wenjing Chen , Hua Tu , Mary L Bouxsein , Patrick R Griffin , Roland Baron , Clifford J Rosen , Lynda F Bonewald , Bruce M Spiegelman |
2018-12-13 | - |
| 28351885 |
RNA Alexis M Onderak , James T Anderson |
2017-06-01 | - |
| 28431250 |
Nuclear Proximity of Mtr4 to RNA Exosome Restricts DNA Mutational Asymmetry. Cell Junghyun Lim , Pankaj Kumar Giri , David Kazadi , Brice Laffleur , Wanwei Zhang , Veronika Grinstein , Evangelos Pefanis , Lewis M Brown , Erik Ladewig , Ophélie Martin , Yuling Chen , Raul Rabadan , François Boyer , Gerson Rothschild , Michel Cogné , Eric Pinaud , Haiteng Deng , Uttiya Basu |
2017-04-20 | - |
| 28378742 |
Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function. Sci Rep Tingting Zhang , Wei Du , Andrew F Wilson , Satoshi H Namekawa , Paul R Andreassen , Amom Ruhikanta Meetei , Qishen Pang |
2017-04-05 | - |
| 27695001 |
Identification of a role for TRIM29 in the control of innate immunity in the respiratory tract. Nat. Immunol. Junji Xing , Leiyun Weng , Bin Yuan , Zhuo Wang , Li Jia , Rui Jin , Hongbo Lu , Xian Chang Li , Yong-Jun Liu , Zhiqiang Zhang |
2016-12-01 | - |
| 26584622 |
Genes Dev. Paulina A Latos , Arnold R Sienerth , Alexander Murray , Claire E Senner , Masanaga Muto , Masahito Ikawa , David Oxley , Sarah Burge , Brian J Cox , Myriam Hemberger |
2015-12-01 |
LOC100044627,
Rpl5,
LOC100862455,
Rpl31,
Ctnnd1,
Cct2,
Cct8,
Smc3,
Ddb1,
Dhx9,
Elf5,
Eomes,
Igf2bp1,
Wdr5,
Hspa5,
Hcfc1,
Hira,
Hspa9,
Ilf3,
Eif6,
Kpna2,
Matr3,
Mbd3,
Mki67,
Map1b,
Myef2,
Myo5a,
Ints6,
Orc1,
Pa2g4,
Pnn,
Rfc1,
Rpl10a,
Rpl19,
Rpl26,
Rpl27,
Rpl28,
Rpl30,
Rpl37a,
Rpl9,
Polr2a,
Rps15,
Sart1,
Scin,
Sin3a,
Snrpc,
Snrpb,
Bptf,
Zfp143,
Ints9,
Tfap2c,
Top1,
Top2b,
Tuba1c,
Ubp1,
Pphln1,
Yy1,
Zfp281,
Emsy,
Grhl2,
Esrrb,
Rpl23a,
Gtf3c4,
Rpl13,
Rpl7a,
Rpl3,
Gtse1,
Iqgap1,
Igf2bp2,
Chd7,
L1td1,
Hist1h1c,
Suz12,
Rplp1,
Prpf40a,
Rbm14,
Akap8,
Snd1,
Hic2,
Rpl23,
Rpl15,
Snrnp40,
Rbm25,
Rpl14,
Eif2s2,
Rpl4,
Hnrnpul2,
Flnc,
Vwa9,
Zcchc8,
Ints10,
Asun,
Skiv2l2,
Zmym2,
Zc3h18,
Rpl18a,
Ints7,
Ehmt1,
Zfp687
|
| 25737280 |
Control of a neuronal morphology program by an RNA-binding zinc finger protein, Unkempt. Genes Dev. Jernej Murn , Kathi Zarnack , Yawei J Yang , Omer Durak , Elisabeth A Murphy , Sihem Cheloufi , Dilenny M Gonzalez , Marianna Teplova , Tomaž Curk , Johannes Zuber , Dinshaw J Patel , Jernej Ule , Nicholas M Luscombe , Li-Huei Tsai , Christopher A Walsh , Yang Shi |
2015-03-01 |
Sf3b3,
Pls3,
Xpo1,
Slc38a1,
Rrn3,
Hat1,
Ogt,
Foxp1,
Atp6v1h,
Pnrc1,
Ppp1r15b,
Pkn2,
Rap1a,
Acat1,
Cse1l,
Abcb7,
Actb,
Prdx3,
Ap1g1,
Arf1,
Arf4,
Arf5,
Arhgap5,
Atp2a2,
Atp5a1,
Atpif1,
Phb2,
Birc6,
Calm1,
Calm2,
Calm3,
Ctnna1,
Ctnnb1,
Cbx3,
Cbx5,
Cct4,
Cct5,
Cct8,
Cdc42,
Copa,
Cox5a,
Cox7a2,
Dpysl2,
Csnk2b,
Ctsb,
Dhx15,
Ddx5,
Dync1h1,
Dst,
Mapre1,
Eef1a1,
Eef2,
Eif3a,
Eif4a1,
Eif4a2,
Eif4g2,
Gdi1,
Gdi2,
Gfpt1,
Ggps1,
Gls,
Glud1,
Rack1,
Pdia3,
H3f3b,
Hdac2,
Hint1,
Hmgcr,
Hn1,
Hnrnpab,
Hnrnpl,
Hspd1,
Hsp90ab1,
Hsp90aa1,
Hspa4,
Hspa9,
Hspe1,
Id3,
Kpnb1,
Eif3e,
Itgb1,
Itm2b,
Kpna4,
Kpna6,
Kras,
Ldha,
Nup155,
Matr3,
Mcl1,
Msh6,
Laptm4a,
Nap1l4,
Ncl,
Nfib,
Ogdh,
Pdcd4,
Slc25a3,
Plaa,
Ppp1cb
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
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| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
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目前还没有研究热点人员