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7172 TPMT

7172

TPMT

thiopurine S-methyltransferase

protein-coding

Homo sapiens

基因描述

Type Description
Definition thiopurine S-methyltransferase

研究结论

Date Results Publications
2021-04-17 13:38:00 Association of thiopurine S-methyltransferase and NUDT15 polymorphisms with azathioprine-induced myelotoxicity in Chinese patients with rheumatological disease. 32187056
2021-03-28 19:07:00 NUDT15 C415T variant compared with TPMT genotyping in predicting azathioprine-induced leucopenia: prospective analysis of 1014 inflammatory bowel disease patients in India. 33111378
2021-03-13 13:19:00 Pharmacogenomics of thiopurines: distribution of TPMT and NUDT15 polymorphisms in the Brazilian Amazon. 32453263
2020-09-19 16:26:00 Retrospective Data Analysis of the Influence of Age and Sex on TPMT Activity and Its Phenotype-Genotype Correlation. 31639757
2020-06-20 12:58:00 We evaluated the role of thiopurine methyltransferase (TPMT) in 6-mercaptopurine (6-MP) sensitivity during treatment of pediatric patients with acute lymphoblastic leukemia 31635813

名称对应

Type IDs
Synonymous TPMTD
Gene
UniProtKB-ID: TPMT_HUMAN, A0A024QZW0_HUMAN
UniprotKB: P51580, A0A024QZW0
UniParc: UPI0000137261
EMBL: U30517, AF019365, AB045146, U81566, U81565, U81567, U12387, BC009596, U30514, AF019369, U81569, U30515, U81568, U81563, U30512, U81564, AL589723, U30518, CH471087, AF019368, U30513, AF021877, AF021876, AF019364, AF019367, U81570, AF035426, U81562, U81573, S62904, AF019366, U81572, U81571, U30516
Ensembl: ENSG00000137364
KO: hsa:7172
Nucleutide sequences
EMBL-CDS: AAC51865.1, AAB71630.1, AAB71629.1, AAB80747.1, AAB71626.1, AAB71636.1, AAB27277.1, AAB71628.1, AAB71632.1, AAB71633.1, AAB71634.1, BAA97037.1, AAC50368.1, AAB71625.1, AAB71635.1, AAC32289.1, AAH09596.1, AAB80746.1, AAC50130.1, AAB71631.1, AAB71627.1, EAW55397.1, EAW55396.1
Gene_ORFName: hCG_1787300
Ensembl_TRS: ENST00000309983
Protein sequencees
Ensembl_PRO: ENSP00000312304
RefSeq: NP_001333747.1, NP_000358.1, NP_001333746.1
Others
UniRef100: UniRef100_P51580
UniRef90: UniRef90_P51580
UniRef50: UniRef50_P51580
UniGene: Hs.444319
CCDS: CCDS4543.1

全选

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