| Type | Description |
|---|---|
| Definition | septin 12 |
| Date | Results | Publications |
|---|---|---|
| 2018-12-22 12:33:00 | We concluded that CDC42 negatively regulates SEPT12 polymerization and is involved in terminal structure formation of sperm heads. | 30189608 |
| 2017-06-10 12:35:00 | Data suggest that SEPT12 phosphorylation inhibits septin ring assembly during annulus biogenesis. | 28346465 |
| 2017-04-22 11:36:00 | In mice sperm with mutated SEPT12, NDC1 dispersed around the manchette region of the sperm head and annulus, compared with concentrating at the sperm neck of wild-type sperm. | 27854341 |
| 2015-12-26 10:56:00 | results demonstrate the molecular architecture of SEPT12 filaments at the sperm annulus, their mechanical support of sperm motility, and their correlation with male infertility. | 25588830 |
| 2011-01-22 11:33:00 | Oocytes fertilized with spermatozoa obtained from Septin 12+/- chimeric mice failed to develop beyond the morula stage after IVF and intracytoplasmic sperm injection because of significant DNA defects in the spermatozoa | 20801438 |
| Type | IDs |
|---|---|
| Synonymous | 1700028G04Rik, 4933413B09Rik, Septin12 |
| Gene |
UniProtKB-ID:
Q9D451_MOUSE,
Q9D9U8_MOUSE,
A0A2R8VJU7_MOUSE
UniprotKB:
Q9D451,
Q9D9U8,
A0A2R8VJU7
UniParc:
UPI0000029E80,
UPI000023C506,
UPI00000E7DF9
EMBL:
AK006458,
BC115618,
AC163723,
AK077091,
AK016798
Ensembl:
ENSMUSG00000022542
|
| Nucleutide sequences |
EMBL-CDS:
BAC36607.1,
AAI15619.1,
BAB30436.1,
BAB24598.1
Ensembl_TRS:
ENSMUST00000170323,
ENSMUST00000229321,
ENSMUST00000230362
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000131062,
ENSMUSP00000155459,
ENSMUSP00000154901
RefSeq:
XP_006522643.1,
NP_083650.1,
XP_006522642.1,
XP_006522640.1,
NP_001360874.1,
NP_081945.1
|
| Others |
UniRef100:
UniRef100_Q9D451,
UniRef100_Q9D9U8,
UniRef100_A0A2R8VJU7
UniRef90:
UniRef90_Q4V8G5,
UniRef90_Q9D451
UniRef50:
UniRef50_Q9D451,
UniRef50_Q4V8G5
UniGene:
Mm.87382
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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