TSPAN6 - tetraspanin 6-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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7105 TSPAN6

基因描述

Type	Description
Definition	tetraspanin 6

研究结论

Date	Results	Publications
2021-02-02 13:25:00	Tetraspanin 7 and its closest paralog tetraspanin 6: membrane organizers with key functions in brain development, viral infection, innate immunity, diabetes and cancer.	32468130
2017-11-11 11:54:00	Results shows that is a crucial player in Amyloid Precursor Protein-C-terminal fragment turnover	28279219
2013-01-05 10:54:00	functions as a negative regulator of the RLR pathway by interacting with MAVS in a ubiquitination-dependent manner.	22908223

名称对应

Type	IDs
Synonymous	T245, TM4SF6, TSPAN-6
Gene	UniProtKB-ID: TSN6_HUMAN, A0A024RCI0_HUMAN, A0A087WZU5_HUMAN, A0A087WYV6_HUMAN UniprotKB: O43657, A0A024RCI0, A0A087WZU5, A0A087WYV6 UniParc: UPI0003583745, UPI0000049052, UPI0000EE6719, UPI0003583743 EMBL: BC012389, AY358825, CR457115, AF133426, AF053453, AB097016, U84895, CH471115, AL035608, AF043906, BT006977 Ensembl: ENSG00000000003 KO: hsa:7105
Nucleutide sequences	EMBL-CDS: BAC77369.1, AAP35623.1, AAH12389.1, EAX02811.1, AAF08365.1, AAC64257.1, AAD00560.1, AAC69710.1, CAG33396.1, AAQ89184.1, EAX02810.1, EAX02809.1 Gene_ORFName: UNQ767/PRO1560, hCG_19468 Ensembl_TRS: ENST00000373020, ENST00000614008, ENST00000612152
Protein sequencees	Ensembl_PRO: ENSP00000362111, ENSP00000482894, ENSP00000482130 RefSeq: NP_001265670.1, NP_001265672.1, NP_003261.1, NP_001265671.1, XP_011529320.1, NP_001265669.1
Others	UniRef100: UniRef100_A0A087WYV6, UniRef100_A0A087WZU5, UniRef100_O43657 UniRef90: UniRef90_O43657, UniRef90_A0A2I2YYN6, UniRef90_A0A087WYV6 UniRef50: UniRef50_G1L609, UniRef50_O43657, UniRef50_A0A2K6FXW8 UniGene: Hs.43233, Hs.587521 CCDS: CCDS14470.1

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
32468130	Tetraspanin 7 and its closest paralog tetraspanin 6: membrane organizers with key functions in brain development, viral infection, innate immunity, diabetes and cancer. Med Microbiol Immunol Brieuc P Perot , MickaÃ«l M MÃ©nager	2020-08-01	-
29987050	Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy. Proc. Natl. Acad. Sci. U.S.A. Tengfei Xiao , Wei Li , Xiaoqing Wang , Han Xu , Jixin Yang , Qiu Wu , Ying Huang , Joseph Geradts , Peng Jiang , Teng Fei , David Chi , Chongzhi Zang , Qi Liao , Jonathan Rennhack , Eran Andrechek , Nanlin Li , Simone Detre , Mitchell Dowsett , Rinath M Jeselsohn , X Shirley Liu , Myles Brown	2018-07-31	-
28514442	Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper	2017-05-25	-
28279219	Tetraspanin 6: a pivotal protein of the multiple vesicular body determining exosome release and lysosomal degradation of amyloid precursor protein fragments. Mol Neurodegener Francesc X Guix , Ragna Sannerud , Fedor Berditchevski , Amaia M Arranz , Katrien HorrÃ© , An Snellinx , Amantha Thathiah , Takaomi Saido , Takashi Saito , Sundaresan Rajesh , Michael Overduin , Samir Kumar-Singh , Enrico Radaelli , Nikky Corthout , Julien Colombelli , SÃ©bastien Tosi , Sebastian Munck , Isabel H Salas , Wim Annaert , Bart De Strooper	2017-03-10	-
26186194	The BioPlex Network: A Systematic Exploration of the Human Interactome. Cell Edward L Huttlin , Lily Ting , Raphael J Bruckner , Fana Gebreab , Melanie P Gygi , John Szpyt , Stanley Tam , Gabriela Zarraga , Greg Colby , Kurt Baltier , Rui Dong , Virginia Guarani , Laura Pontano Vaites , Alban Ordureau , Ramin Rad , Brian K Erickson , Martin WÃ¼hr , Joel Chick , Bo Zhai , Deepak Kolippakkam , Julian Mintseris , Robert A Obar , Tim Harris , Spyros Artavanis-Tsakonas , Mathew E Sowa , Pietro De Camilli , Joao A Paulo , J Wade Harper , Steven P Gygi	2015-07-16	-
23533145	In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine. Proteomics Simona Principe , E Ellen Jones , Yunee Kim , Ankit Sinha , Julius O Nyalwidhe , Jasmin Brooks , O John Semmes , Dean A Troyer , Raymond S Lance , Thomas Kislinger , Richard R Drake	2013-05-01	-
22091964	Identification of genomic deletions spanning the PCDH19 gene in two unrelated girls with intellectual disability and seizures. Clin. Genet. A K Vincent , A Noor , A Janson , B A Minassian , M Ayub , J B Vincent , C F Morel	2012-12-01	PCDH19, TSPAN6
22908223	Tetraspanin 6 (TSPAN6) negatively regulates retinoic acid-inducible gene I-like receptor-mediated immune signaling in a ubiquitination-dependent manner. J Biol Chem Yetao Wang , Xiaomei Tong , Ehimwenma Sheena Omoregie , Wenjun Liu , Songdong Meng , Xin Ye	2012-10-05	-
21900206	A directed protein interaction network for investigating intracellular signal transduction. Sci Signal Arunachalam Vinayagam , Ulrich Stelzl , Raphaele Foulle , Stephanie Plassmann , Martina Zenkner , Jan Timm , Heike E Assmus , Miguel A Andrade-Navarro , Erich E Wanker	2011-09-06	KCNE3, HDAC6, PDCD6IP, ZNF605, TOM1L1, HMGXB4, RANBP9, RWDD2B, SNUPN, TSSC4, ARPC3, ACTR1B, CDH13, CEBPZ, RBM5, CDK4, CDK5, TRIM13, EIF1, DDX39A, HNRNPR, RABEPK, SPRY2, CDKN1A, CDK2AP2, LOC400927-CSNK1E, RGS19, CDKN2B, DSCR3, IKZF1, NPM3, TUBA1B, TUBB3, RACK1, PIAS3, NDC80, YAP1, CDIPT, TUBGCP3, TIMM17A, TAB1, FST, STK25, DEAF1, KAT5, GLRX3, DCTN2, PRDX4, RABAC1, DPYSL4, CCT7, CCT4, DRAP1, CENPB, TXNIP, NPRL2, GNB5, CERS1, CFL1, MGEA5, PLK4, RAI1, GIPC1, ZNF266, UTP14A, PGRMC1, RAB10, YIF1A, JTB, GADD45G, AFG3L2, C11orf58, HNRNPA0, PNRC1, ADIRF, COPS6, IMMT, SF3B2, KIF2C, RAB31, ADAP1, PIM2, RCC1, NUDT21, SNRNP35, CHD3, STMN2, HSF2BP, SPACA9, RPP14, FGFR1OP, FAF1, ZWINT, CHGA, CDC37, CHGB, KAT7, C14orf1, NUDT5
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-

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