| Type | Description |
|---|---|
| Definition | transforming growth factor beta 1 induced transcript 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-23 12:59:00 | Increased expression of the transforming growth factor beta-inducible gene HIC-5 in systemic sclerosis skin and fibroblasts: a novel antifibrotic therapeutic target. | 32442272 |
| 2020-09-26 13:08:00 | HIC-5 in cancer-associated fibroblasts contributes to esophageal squamous cell carcinoma progression. | 31740661 |
| 2020-06-27 11:53:00 | Results reveal novel regulation of vimentin organization/dynamics by the FA scaffold protein Hic-5 via modulation of RhoGTPases and downstream formin activity. | 31644368 |
| 2020-06-06 11:25:00 | The molecular mechanism involved in Hic-5-mediated invasion. | 31683179 |
| 2019-08-10 12:42:00 | HIC-5 regulates mitochondrial production in tumor cells while requiring activated KRAS to mediate its effect on NOX4 in oncogene-induced senescence and tumor invasiveness. | 30281903 |
| Type | IDs |
|---|---|
| Synonymous | ARA55, HIC-5, HIC5, TSC-5 |
| Gene |
UniProtKB-ID:
TGFI1_HUMAN,
A0A024QZE7_HUMAN
UniprotKB:
O43294,
A0A024QZE7
UniParc:
UPI00001FFFA9,
UPI000006F14C
EMBL:
AB007836,
BC032545,
BC001830,
AK313327,
CH471192,
BC001507,
AF116343,
BC017288,
DQ309025
Ensembl:
ENSG00000140682
KO:
hsa:7041
|
| Nucleutide sequences |
EMBL-CDS:
AAD22552.1,
EAW52126.1,
AAH01507.2,
AAH01830.1,
AAH17288.1,
BAG36132.1,
AAH32545.1,
BAA24799.1,
ABB96286.1,
EAW52128.1,
EAW52130.1
Gene_ORFName:
hCG_1772006
Ensembl_TRS:
ENST00000361773,
ENST00000567607,
ENST00000394858,
ENST00000394863
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000378327,
ENSP00000457586,
ENSP00000355117,
ENSP00000378332
RefSeq:
NP_001035919.1,
NP_001158191.1,
XP_024306180.1,
NP_057011.2
|
| Others |
UniRef100:
UniRef100_O43294
UniRef90:
UniRef90_O43294
UniRef50:
UniRef50_O43294
UniGene:
Hs.513530
CCDS:
CCDS42156.1,
CCDS10713.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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